Clinical trials: Soreness, Muscle
Muscle Soreness
Effects of Riboflavin in Mitigating Muscle Soreness in Ultra-marathon Athletes
The aim of this project is to investigate the effects of riboflavin, also known as vitamin B2, on preventing delayed onset muscle soreness (DOMS) in ultramarathon athletes through a randomized placebo-controlled study.
- Trial name
- NCT05907850
- Testing
- Riboflavin
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Steven Moore
Inflammation, Muscle Recovery
The Effect of Aspalathus Linearis on Muscle Soreness and Post-exercise Recovery in Young, Physically Inactive Women
Exercise has been found to exert beneficial effect on overall health. However, it also induces muscle damage at the same time. This then leads to muscle pain, temporary inflammation and reduced muscle function.
- Conditions
- Inflammation, Muscle Recovery, Muscle Soreness
- Trial name
- NCT06561750
- Testing
- Rooibos tea, Control
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Recovery Methods, Exercise and Recovery
Effects of Carnitine Supplementation on Exercise-Induced Muscle Damage: A Randomized Controlled Trial
This clinical study aims to investigate the effects of L-carnitine supplementation on recovery following high-intensity interval exercise in young athletes.
- Conditions
- Recovery Methods, Exercise and Recovery, Exercise Fatigue, Carnitine Ingestion
- Trial name
- NCT07492446
- Testing
- L-Carnitine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Healthy
The Effect of Thermotherapy on Recovery and Performance
This study investigates the effects of cooling on the recovery and performance characteristic in young healthy subjects. The study is divided in two projects: Project A: investigates the effects of 20 min.
- Trial name
- Cryotherapy (NCT02506283)
- Testing
- Zamar Therapy CT clinic
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Sports Physical Therapy
Comparative Effects of High and Moderate Intensity Resistance Training in Young Football Players
Football playing is an intermittent sport requiring high intensity dynamic movements, such as acceleration, sprinting and jumping. Higher levels of strength and power are crucial for young football players.
- Trial name
- NCT06479551
- Testing
- high intensity-low volume resistance training, Moderate intensity-high volume resistance training
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Muscle Soreness
Investigating the Effects of Different Soft Tissue Mobilizations on Delayed Onset Muscle Soreness
Delayed onset muscle soreness (DOMS) is associated with the initiation of a new physical activity or a sudden increase in exercise volume and intensity.
- Trial name
- NCT04248764
- Testing
- Foam roller application, Massage application
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Hamstring Injury, Muscle Tone Increased
Cranial Laser Reflex Technique for Hamstring Function
Purpose: To conduct a pilot study of the effect of Cranial Laser Reflex Technique (CLRT) compared with sham laser on hamstring muscle flexibility, strength, and pain pressure threshold.
- Conditions
- Hamstring Injury, Muscle Tone Increased, Muscle Pain, Muscle Weakness
- Trial name
- CLRTHam (NCT03044106)
- Testing
- CLRT
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pain, Delayed Onset Muscle Soreness
Phase II Study of AP0302 5% Versus a Vehicle Comparator
This study is designed to evaluate the analgesic safety and efficacy of study drug (AP0302) applied topically every 6 hours as compared to a vehicle, in subjects experiencing delayed onset muscle soreness.
- Trial name
- NCT02324985
- Testing
- S-Ibuprofen Topical Gel 5%, Vehicle Topical Gel
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Aponia Laboratories, Inc.
Shoulder Pain, Healthy Volunteers
Sensory Processing and Musculoskeletal Shoulder Pain
The development of chronic pain is a common complication in shoulder pain conditions. Half of these type of patients exhibit persistent pain even after a period of six to twelve months from the start of their pain treatment.
- Trial name
- NCT05368649
- Testing
- Short-wave diathermy
- Where
- Argentina
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Analysis of Post-exertional Malaise Using a Two-day CPET in People With ME/CFS
This study aims to collect and identify key outcome measures or disease parameters in ME/CFS that are altered during elevated symptoms relative to baseline by gathering information before and after symptom provocation using a…
- Trial name
- NCT04026425
- Testing
- Two-day cardiopulmonary exercise test
- Where
- 3 sites in United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Ithaca College
Human Immune Response
Effects of Palmar Cooling on the Human Immune System
This is a research study on human exercise that will investigate the immune system response post-exercise and how it relates to Delayed Onset Muscle Soreness (DOMS), and possible causes for DOMS.
- Trial name
- NCT07215338
- Testing
- Muscle Temperature Control
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Stanford University
Immune Markers, Complete Blood Count (CBC) With Platelet Differentials
Immune and Recovery Modulating Impact of Probiotic Supplementation After Intense Resistance Exercise
This study proposal seeks to examine the efficacy of probiotic supplementation at mitigating changes in immune function and recovery after completion of intense, stressful exercise while also allowing for a better understanding…
- Conditions
- Immune Markers, Complete Blood Count (CBC) With Platelet Differentials, Muscle Damage, Muscular Force Production
- Trial name
- NCT04441840
- Testing
- Active Probiotic Culture, Inactive Probiotic Culture
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Musculoskeletal Pain, Athletic Injuries
Single Focused Shock Wave in the Release od Delayed Onset Muscle Soreness (DOMS)
The study is a single-center, double blinded, randomized controlled trial aimed to investigate the effects of focused extracorporeal shockwave therapy (fESWT) on Delayed Onset Muscle Soreness (DOMS) of the non-dominant biceps…
- Trial name
- NCT02548208
- Testing
- Verum focused extracorporeal shockwave
- Where
- Germany
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Dr. Johannes Fleckenstein
Delayed Onset Muscle Soreness
Comparison of Dry Needle and Massotherapy on Tolerance Effort and Soreness
Introduction: Delayed onset muscle soreness (DOMS) is a common myogenic condition considered to be a muscle tension injury frequently observed in recreational or experienced athletes, induced in the majority of cases by eccentric…
- Trial name
- NCT03619928
- Testing
- Dry needling, Massotherapy
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Pain, Acute
Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity
This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities.
- Trial name
- NCT06411197
- Testing
- Hypertonic saline injection, Isotonic saline injection
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kristian Kjær Petersen
Sports Nutrition, Protein Supplementation
Acute Whey Protein And Casein Supplementation: Effect On Protein Metabolism After Resistance Exercise
The proteins of human breast milk are the most important endocrine signaling system that promotes neonatal growth by increasing the release of insulin, insulin-like growth factor-1 (IGF-1), and the leucine-mediated mammalian…
- Trial name
- NCT04648384
- Testing
- Blend Protein Supplementation, Resistance Exercise
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Fatigue Syndrome, Burnout
A Longitudinal Study on Longstanding Complicated Fatigue
The purpose of the study is to investigate if there are common biopsychosocial vulnerability factors for developing and maintaining fatigue, regardless of the diagnosis.
- Conditions
- Chronic Fatigue Syndrome, Burnout, Covid19
- Trial name
- NCT04955587
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Pain, Weakness
Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms
This study will evaluate whether a dietary supplement, coenzyme Q10 (CoQ10), will improve muscle symptoms, such as muscle aches, pains, cramps, and/or weakness, which are experienced by some individuals who use statin medications.
- Conditions
- Pain, Weakness, Cramps, Myalgia or Myositis Nos
- Trial name
- NCT01032993
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Catherine Buettner
Fasciculation
Effects of Cisatracurium on Succinylcholine-induced Fasciculations and Myalgia
The purpose of this study is to investigate the effects of different doses of cisatracurium pretreatment on succinylcholine-induced fasciculations and postoperative myalgia.
- Trial name
- NCT02481193
- Testing
- Cisatracurium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yangzhou No.1 People's Hospital
Sports Physical Therapy
Comparison of Active and Passive Static Stretching in Delayed Onset of Muscle Soreness of Recreational Body Builders
To find out the better treatment options from active and passive static stretching in delayed onset of muscle soreness in recreational body players.
- Trial name
- NCT04636281
- Testing
- Active and passive static stretching exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Riphah International University