Clinical trials: Soreness, Muscle
Healthy
Capsaicin-induced Muscle Pain in Humans
There is currently no specific diagnostic test for primary muscular pain. The present study investigates whether selective blockade of the suprascapular nerve can effectively abolish experimental pain arising from the…
- Trial name
- NCT02377180
- Testing
- Intramuscular capsaicin injection, Suprascapular nerve block, Local anesthetic infiltration
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Signs and Symptoms, Fever
Biomedical Signal Extraction From Symptom Descriptions: An Observational Registry Using the OpenGenome Platform
This registry prospectively collects anonymized free-text symptom descriptions submitted voluntarily by adults through the OpenGenome platform at opengenome.bio.
- Conditions
- Signs and Symptoms, Fever, Myalgia, Skin Diseases
- Trial name
- OGNOME-REG (NCT07578610)
- Testing
- OpenGenome AI Platform
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- OpenGenome
Muscle Soreness
Effect of Acheta Domesticus Supplementation on Post-Exercise Muscle Recovery in Recreationally Active Male
The goal of this clinical trial is to test the effect of house cricket (Acheta domesticus) supplementation for strength recovery in recreationally active males.
- Trial name
- NCT06096389
- Testing
- 100 Drop Jumps, Whey supplementation, Carbohydrate supplementation
- Where
- Malaysia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Delayed Onset Muscle Soreness (DOMS), Inflammation
Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion
The goal of this clinical trial is to learn if applying cold therapy can reduce swelling, inflammation, and pain after physical activity in adults who experience muscle soreness (Delayed Onset Muscle Soreness, or DOMS).
- Conditions
- Delayed Onset Muscle Soreness (DOMS), Inflammation, Muscle Pain, Muscle Damage
- Trial name
- NCT06813690
- Testing
- Cold Therapy with Axanova Cold Hot Pearls Maxi Pack
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Immune Markers, Complete Blood Count (CBC) With Platelet Differentials
Immune and Recovery Modulating Impact of Probiotic Supplementation After Intense Resistance Exercise
This study proposal seeks to examine the efficacy of probiotic supplementation at mitigating changes in immune function and recovery after completion of intense, stressful exercise while also allowing for a better understanding…
- Conditions
- Immune Markers, Complete Blood Count (CBC) With Platelet Differentials, Muscle Damage, Muscular Force Production
- Trial name
- NCT04441840
- Testing
- Active Probiotic Culture, Inactive Probiotic Culture
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Exercise Induced Muscle Damage
Indirect Biomarkers and Exercise Induced Muscle Damage
The purpose of this study is to investigate the magnitude of changes in biomarkers of exercise-induced muscle damage following an acute bout of eccentric exercise of the knee extensors performed on an isokinetic dynamometer.
- Trial name
- NCT07503860
- Testing
- Eccentric Exercise
- Where
- Greece
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vassilis Paschalis
Delayed Onset Muscle Soreness
Effects of Foam Roller Versus KT Tape on Delayed Onset Muscle Soreness
Objective of this study is to compare the effects of foam roller with KT tape on DOMS. The university going students will be divided in two groups, with one group receiving Kinesio Tape as intervention and other Foam Rolling as…
- Trial name
- NCT06076356
- Testing
- Foam Rolling, Kinesio Taping
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Bandages, Muscle Soreness
Kinesio Taping in Muscle Damage Response Induced by Eccentric Exercise
Sixty volunteers with a mean age of 21,8 ± 2,6 years participated in this study, randomly distributed into one of the following groups: control, Kinesio taping group with tension in the anterior arm region and Kinesio taping…
- Trial name
- NCT02945098
- Testing
- Kinesio Taping
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Delayed Onset Muscle Soreness
Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery
Both BFR and intermittent pneumatic compression are purported to decrease symptoms associated with exercise induced muscle damage (EIMD) that cause delayed onset muscle soreness (DOMS).
- Trial name
- NCT06815367
- Testing
- Pneumatic Compression, Blood Flow Restriction
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Long COVID, PTLDs
A Prospective Study to Evaluate the Role of T-Cell Dysfunction in Patients Who Present Symptoms Associated With Long COVID, Lyme Disease and Myalic Encephalomyelitis / Chronic Fatigue Syndrome Using the Vira Immune Fluorospot T Cell Assay
This is a longitudinal observational study recruiting individuals that have attended three clinical sites with symptoms associated with a diagnosis of long COVID, PTLDS or ME/CFS.
- Conditions
- Long COVID, PTLDs, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3)
- Trial name
- NCT06731179
- Where
- 3 sites in United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- ViraxBio Labs
Delayed Onset Muscle Soreness (DOMS), Healthy
Posterior Chain Responses to Gastrocnemius DOMS
The goal of this clinical trial is to learn how delayed onset muscle soreness (DOMS) in the calf muscle (gastrocnemius) affects the muscles of the posterior chain and physical performance in healthy young adults.
- Trial name
- NCT07324395
- Testing
- Gastrocnemius DOMS Induction Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ebru Aloğlu Çiftçi
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Therapeutic Ultrasound for Muscle Recovery After Muscle Fatigue Exercise
This randomized, parallel, placebo-controlled, double-blind clinical trial will evaluate the effects of low-intensity therapeutic ultrasound on muscle recovery after a fatiguing handgrip exercise protocol in healthy adults.
- Trial name
- NCT07871942
- Testing
- Pulsed Low-Intensity Therapeutic Ultrasound
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Sports Physical Therapy
Comparison of Active and Passive Static Stretching in Delayed Onset of Muscle Soreness of Recreational Body Builders
To find out the better treatment options from active and passive static stretching in delayed onset of muscle soreness in recreational body players.
- Trial name
- NCT04636281
- Testing
- Active and passive static stretching exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Delayed Onset Muscle Soreness (DOMS), Exercise-Induced Muscle Soreness
A Study of Mitragynine Formulations for Exercise-Induced Muscle Soreness in Healthy Adults
This Phase II randomized, double-blind, placebo-controlled study will evaluate the safety, tolerability, and physical dependence potential of mitragynine-containing formulations after 28 days of use and assess their effects on…
- Trial name
- NCT07809282
- Testing
- SpecioTea, MitraPlex
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Traditional Naturals Research Inc.
Delayed Onset Muscle Soreness
Effects of Percussive Massage Treatment With Theragun on Post Exercise Delayed Onset Muscle Soreness
This project will be Randomized control trial conducted to check the effects of percussive massage treatment with theragun on pain and muscle length on post exercise delayed onset muscle soreness (DOMS) of calf muscles in healthy…
- Trial name
- NCT05026944
- Testing
- Percussive massage and static stretching exercises, static stretching exercises
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Intubating Conditions, Postoperative Myalgia
Comparing Intubating Conditions Using Succinylcholine or Rocuronium for Rigid Bronchoscopy
Succinylcholine is commonly used for neuromuscular relaxation for short procedures such as rigid bronchoscopy. A more modern alternative is the application aof rocuronium, reversed by sugammadex.
- Conditions
- Intubating Conditions, Postoperative Myalgia, Patient Satisfaction
- Trial name
- NCT01996358
- Testing
- Succinylcholine, Rocuronium 0,3, Rocuronium 0,6
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Pain, Delayed Onset Muscle Soreness
An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS
The purpose of this study is to evaluate analgesic efficacy of Topical Voltaren Gel (diclofenac sodium gel) 1% applied QID compared to Placebo in Subjects Experiencing Delayed Onset Muscle Soreness.
- Trial name
- NCT02087748
- Testing
- 1% diclofenac sodium gel
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lotus Clinical Research, LLC
Insomnia, Healthy Adult
The Impact of Insomnia on Pain Sensitivity and the Trajectory of Exercise-induced Muscular Pain
Sleep is a critical determinant of physiological recovery and pain regulation. Growing evidence suggests that sleep disruption directly heightens central and peripheral pain sensitivity to sensory stimuli (e.g., mechanical…
- Conditions
- Insomnia, Healthy Adult, Musculoskeletal Pain, Pain Sensitivity
- Trial name
- NCT07827664
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Pain, Face
Botox vs Occlusal Splint for Masseter Pain
This randomized clinical trial will compare the standard treatment (occlusal splint) and botox for the treatment of face muscular pain in adults.
- Trial name
- NCT03456154
- Testing
- Botox Injectable Product, Occlusal splint
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Delayed Onset Muscle Soreness
Effects of Allicin Pretreatment on Anti-oxidation Ability and Delayed Onset Muscle Soreness
To investigate the effects of allicin pretreatment on delayed onset muscle soreness (DOMS), muscle function, and oxidative stress following eccentric exercise
- Trial name
- NCT07812688
- Testing
- allicin
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Guangxi Normal University