Clinical trials: Sting
HIV
Spironolactone and XPB-1 Integrity in the TFIIH Complex
This is a prospective, interventional, exploratory clinical study designed to evaluate the pharmacokinetics, safety, and biological effects of spironolactone on the degradation of the XPB (ERCC3) protein and its potential impact…
- Trial name
- SPIRIT-XPB (NCT07415811)
- Testing
- Spironolactone (drug)
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Dental Occlusion, Occlusal Analysis
Trueness of Digital Occlusal Analysis
The aims of this observational study are to evaluate the trueness of two different digital occlusal analyzers; handheld occlusal analyzer versus intraoral scanner in comparison to conventional methods in identifying true occlusal…
- Trial name
- NCT06672627
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Bites, Human
Biting Force in Heat Cured Acrylic Resin Versus CAD/CAM Maxillary Single Denture Bases
measuring difference in biting force between (computer aided design/computer aided manufacturing) maxillary dentures and conventional ones.
- Trial name
- NCT02996123
- Testing
- cad/cam maxillary dentures
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obturation
The Effect of Clinical Experience on the Quality of Obturation and Periapical Changes of Teeth Treated With Matched Cones in Combination With Bioceramic Sealer
Evaluation of the impact of clinical experience on the quality of obturation and periapical changes of clinical cases using lateral compaction with bioceramic sealers and matched cone obturation with bioceramic sealers both…
- Trial name
- NCT06260423
- Testing
- Experienced dentist using lateral compaction with bioceramic sealer., Unexperienced dentist using lateral compaction with bioceramic sealer., Experienced dentist using Single cone with bioceramic sealer.
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Occlusion
Effects of Clear Aligners Versus Fixed Appliances on Occlusion After Treatment of Mild Anterior Crowding
The aim of this study is to evaluate effects of clear aligners versus fixed appliances on occlusion after treatment of mild anterior crowding a T-scan study.
- Trial name
- NCT05737290
- Testing
- Clear aligners, Fixed appliances
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Occlusion
Occlusal Forces and Muscle Activity in Fixed Versus Removable Mandibular Implant Supported Overdenture
22 Patients having lower completely edentulous mandible aged 55-60 years were selected from the outpatient dental clinic of the Medical Excellence Centre of the National Research (NRC) Cairo, Egypt.
- Trial name
- NCT05949151
- Testing
- dental implants (K1 line conical connection double thread, OXY, Italy), Occlusense (Bausch GmbH & Co. KG), electromyography (EMG) (Nemus II)".
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Asmaa Nabil Elboraey
Caries, Dental
The Effects of Stainless Steel Crowns Applied With Hall Technique on Occlusal Vertical Dimension
In recent years restoring carious of fractured primary teeth with stainless steel crowns (SSC) has became more popular than ever.
- Trial name
- NCT03010618
- Testing
- Hall technique stainless steel crowns
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Rheumatoid Arthritis, Osteoarthritis
Low Dose Dexamethasone in Supraclavicular Blocks
Brachial plexus nerve blocks provide superior analgesia over opioids while avoiding unwanted side effects. Single shot blocks with local anesthetic alone usually do not last the duration of the acute post-surgical pain period.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Nerve Entrapment, Ligament Injury
- Trial name
- NCT02666443
- Testing
- Control intervention (no dexamethasone), Peri-neural Dexamethasone 1 mg, Intravenous Dexamethasone 1 mg
- Where
- Canada
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Biting
Comparative Study of Biting Force of Injection Molded PEEK and Bre.Flex for Removable Partial Dentures.
The aim of the present study is to evaluate the biting force of upper removable partial denture constructed from two different flexible thermoplastic materials.
- Trial name
- NCT03038737
- Testing
- bre.flex, PEEK
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Occlusion, Crowns
Occlusal Adjustment Time and Volume for Single Unit Fixed Prosthesis Fabricated With Different Virtual Mounting
Regardless of the fabrication workflow occlusal adjustments seem to be inevitable during delivery of indirect fabrication of the restoration.
- Trial name
- NCT05471024
- Testing
- Digitized Mounted Articulator Scan, Average Positioning on Virtual Bonwill Triangle, Digital Face Scan
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cairo University
Training, Exercise
Hypoalgesic Effects of Exercise and Training of Different Modalities
Further research is needed to explore the analgesic effects of post-acute and chronic exercise and if effects are partially dependent on lower H-reflex/V-wave inhibition by group III and IV muscle afferents desensitization.
- Conditions
- Training, Exercise, Fatigue, Occlusion
- Trial name
- NCT07105410
- Testing
- Aim #1: The effect of post-exercise circulatory occlusion on H-reflex and V-wave, Aim #2: The hypoalgesic effects of acute exercise of different modalities, Aim #3: The hypoalgesic effects of chronic training of different modalities
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Opioid Consumption, Postoperative, Pain, Postoperative
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over…
- Conditions
- Opioid Consumption, Postoperative, Pain, Postoperative, Nerve Block, PENG Block
- Trial name
- NCT06821516
- Testing
- Evaluation of the postoperative analgesic effectiveness of PENG block in participants undergoing total hip arthroplasty under spinal anesthesia, Evaluation of the postoperative analgesic effectiveness of lumbar erector spinae block in participants undergoing total hip arthroplasty under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Latrodectism
Pharmacokinetic Study Protocol of ANAWIDOW Lyophilized Powder for Solution for Intravenous Use in Fasting Conditions
A single-dose, open-label, single-treatment, single-period pharmacokinetic study under fasting conditions, in 12 healthy adult. To evaluate the single dose pharmacokinetic profile ANAWIDOW [antivenin latrodectus (black widow)…
- Trial name
- NCT04848714
- Testing
- ANAWIDOW [antivenin latrodectus (black widow) equine immune F(ab)2] lyophilized powder for solution 10 mL
- Where
- Mexico
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Dental Pulp Necrosis
The Effect of Sealer Type and Obturation Technique on Postoperative Pain
Postoperative pain is an important consideration in endodontic treatment, and its incidence may be influenced by both obturation technique and sealer type.
- Trial name
- pain (NCT07386197)
- Testing
- Obturation of root canals
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Anesthesia, Block
Evaluating the Effectiveness of Bilateral ESPB in Addition to Standard Analgesia at Reducing Opioid Consumption
Study the benefits of a Erector Spinae nerve block for pain control and decrease narcotics usage after mammoplasty in an ambulatory setting
- Trial name
- NCT03954249
- Testing
- Erecto Spinae nerve block, Multimodal Analgesia
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Pain
Pilot Study of the Effect of Transcutaneous Stimulation of the Vagus Nerve on Pain Perception and Parameters of the Autonomic Nervous System
The increased incidence of pain syndromes requires the investigation of pathophysiological coherences as well as searching for new therapies.
- Trial name
- NCT01174498
- Testing
- Cerbomed t-VNS® transcutaneous stimulation
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- cerbomed GmbH
Postoperative Analgesia, Transversus Abdominis Plane (TAP) Block
Transversalis Fascia Plane Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Children
This prospective clinical study aims to compare the postoperative analgesic efficacy of the ultrasound-guided transversalis fascia plane block (TFPB) and the transversus abdominis plane (TAP) block in pediatric patients…
- Conditions
- Postoperative Analgesia, Transversus Abdominis Plane (TAP) Block, Transversalis Fascia Plane Block, Pediatric Surgical Procedures
- Trial name
- NCT07242196
- Testing
- Postoperative analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Postoperative Pain, Cesarean Section Complications
Effect of Quadratus Lumborum Block in C/S
to compare postoperative analgesic effects of USG guided QLB-2 and QLB-3 blocks after C/S. We hypothesized that QLB-3 may be more effective for pain relieving than QLB-2 after C/S.
- Conditions
- Postoperative Pain, Cesarean Section Complications, Block, Patient Satisfaction
- Trial name
- NCT04733313
- Testing
- ultrasound guıded quadratus lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Cracked Tooth Syndrome
Exploration of Diagnosis, Etiology, and Prognosis Prediction of Cracked Teeth in Young Adults
Cracked teeth are a common dental problem where tiny cracks form in the teeth. These cracks can be hard to find early, and if not treated, they may cause the tooth to break.
- Trial name
- CDCP (NCT07837960)
- Testing
- Observational Assessment Only
- Where
- China
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Psoriasis
Study of a New Dressing for Use With Topical Medications
The purpose of this study is to determine if a new dressing designed to be used with topical medications will enhance the effects of these topical medications.
- Trial name
- NCT00234728
- Testing
- Occlusive dressing
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Teikoku Pharma USA, Inc.