Clinical trials: Stroke, Chronic
Stroke, Spasticity
Effectiveness of Dry Needling (DNHS Technique) in Patients With Chronic Stroke
Study hypothesis: The DNHS technique, performed via one session of deep dry needling of myofascial trigger points applied to the biceps brachii, brachialis, flexor digitorum superficialis, flexor digitorum profundus, triceps…
- Trial name
- NCT03546517
- Testing
- Dry Needling
- Where
- Spain
- Volunteers
- 23 people
- Sponsor
- Universidad San Jorge
Aphasia
Speeded Anomia Treatment in Chronic Post-stroke Aphasia
The main aim of the study is to investigate the effect of a novel, speeded anomia therapy (Conroy et al., 2018) in a large population of patients with chronic post-stroke aphasia.
- Trial name
- NCT05512884
- Testing
- Speeded anomia therapy
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Cambridge
Muscle Spasticity
Bilateral Versus Unilateral Task Retraining Using the SaeboFlex Orthosis
A small, pilot study consisting of twelve participants with subacute (6-12 months post-stroke)and chronic stroke (1year+ post-stroke)living in and around Columbia area.
- Trial name
- NCT00893776
- Testing
- Task Training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Missouri-Columbia
Chronic Stroke Patients
Effects of Backward Gait Training in Chronic Stroke Patients
Loss of motor control after stroke, muscle weakness, abnormal movement patterns, spasticity, range of motion limitations and sensory dysfunction, resulting in a decrease in the load transferred to the affected limb, changes in…
- Trial name
- NCT04903392
- Testing
- Backward Walking Training, Forward Walking Training
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Bandırma Onyedi Eylül University
Brain Injuries, Stroke
Effects of Prolonged and Chronic Critical Illness Induced by Brain Injury on Metabolic State
Brain injuries, including acute stroke (AS) and traumatic brain injury (TBI), are prevalent pathologies with severe consequences.
- Conditions
- Brain Injuries, Stroke, Malnutrition, Critical Illness
- Trial name
- NCT06545825
- Testing
- Standard enteral nutrition
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology
Consciousness Disorders, Persistent Vegetative State
Multimodal Assessment and Prognosis in Disorders of Consciousness After Severe Brain Injury (CyDoC-MAP)
After a severe brain injury some patients survive but cannot communicate, and deciding early which of them are likely to recover consciousness remains one of the hardest problems in neurocritical care.
- Conditions
- Consciousness Disorders, Persistent Vegetative State, Unresponsive Wakefulness Syndrome, Minimally Conscious State
- Trial name
- CyDoC-MAP (NCT07736820)
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- Nicosia General Hospital
Cerebrovascular Accident, Hemiplegia
The Effect of Different Schedules of Functional Task Practice for Improving Hand and Arm Function After Stroke
The first purpose of this study is to determine how often people should practice motor skills to best improve the ability to use the affected arm and hand after stroke.
- Trial name
- NCT00361660
- Testing
- functional task practice - distributed, functional task practice - condensed
- Sponsor
- US Department of Veterans Affairs
Acute Ischemic Stroke, Intracranial Arterial Stenosis
Post-Market Active Surveillance and Health Economic Evaluation of Cerebrovascular Diagnostic and Therapeutic Devices
The research focuses on "post-market active surveillance and health economic evaluation of non-pharmacological therapies and innovative cerebrovascular diagnostic and therapeutic devices".
- Conditions
- Acute Ischemic Stroke, Intracranial Arterial Stenosis, Extracranial Arterial Stenosis, Intracranial Aneurysms
- Trial name
- NCT07828379
- Testing
- Endovascular Treatment for Acute Ischemic Stroke
- Volunteers
- 2,000 people
- Sponsor
- Changhai Hospital
Healthy Volunteers, Spinal Cord Injury
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
This is an early feasibility trial to determine whether transcutaneous neuromuscular electrical stimulation, with or without transcutaneous spinal cord stimulation, using an investigational neurostimulation device improves…
- Conditions
- Healthy Volunteers, Spinal Cord Injury, Stroke, Paralysis
- Trial name
- NCT04755699
- Testing
- Transcutaneous Electrical Stimulation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Stroke
Portable EMG-triggered Hand Robot for Individuals After Stroke
This is an interventional pilot study investigating the feasibility of using the hand of hope (HOH) device for individuals with decreased hand function after stroke.
- Trial name
- NCT02364700
- Testing
- Hand of Hope (HOH)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Rehab-Robotics Company Limited
Stroke, Plegia
Treatment of Chronic Stroke With AMES + EMG Biofeedback
The purpose of this study is to determine if individuals who had a stroke more than one year before entering the study and who remain unable to open their affected hand are better able to sense and move their affected arm after…
- Conditions
- Stroke, Plegia, Paresis, Cerebrovascular Accident
- Trial name
- AMES (NCT01116544)
- Testing
- AMES Therapy (assisted movement and enhanced sensation)
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- AMES Technology
Chronic Post-stroke Headache
TMS and Exercise for Post-stroke Pain
There are over 7 million people living with stroke in the United States. Per year, approximately 17,000 Veterans are admitted to the VA for acute stroke. Chronic pain after stroke can occur between 10-50% of stroke survivors.
- Trial name
- NCT04672044
- Testing
- Active rTMS and exercise
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Stroke
Vestibular Training on Community Ambulation and Fall Risk in Stroke
Nearly half of individuals with stroke experience limitations in community ambulation, and 35.7% of community-dwelling stroke survivors experienced falls while walking, indicating that falls are common during routine daily…
- Trial name
- NCT07494500
- Testing
- Vestibular training, Conventional physical therapy
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Yang Ming Chiao Tung University
Chronic Subdural Hematoma, Anticoagulant-induced Bleeding
Management of Anticoagulants and Antithrombotics in Patients With CSDH
Primary objective of the study will be to compare, up to 6 months after surgery, number of relapses (post operative re-bleeding) or intracerebral hemorrhage (others than subdural hematomas) and thromboembolic or cardiovascular…
- Conditions
- Chronic Subdural Hematoma, Anticoagulant-induced Bleeding, Thromboembolic Stroke, Cardiovascular Stroke
- Trial name
- THERCA (NCT05079295)
- Testing
- CSDH evacuation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University Hospital of Ferrara
Stroke, Cognitive Impairment
A Sitting Tai Chi Programme for Chronic Stroke Survivors With Post-stroke Cognitive Impairment
Introduction Stroke remains the third leading cause of death and disability combined. Post-stroke cognitive impairment (PSCI) is a common neurological sequela that may affect up to 80% of stroke survivors.
- Trial name
- NCT07512739
- Testing
- Tai Chi
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Chinese University of Hong Kong
Chronic Heart Failure
The IMPULSE Study: Pilot
Continuous-flow (CF) left ventricular assist devices (LVADs) are an important tool in the treatment of end-stage heart failure, affording patients significantly improved quantity and quality of life.
- Trial name
- IMPULSE (NCT02044471)
- Testing
- Remote Ischemic Conditioning (using Sphygmomanometer)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Chronic Aphasia
Computerised Therapy in Chronic Stroke
The few studies looking systematically into the neurophysiological and neuropsychological components of available therapies for chronic aphasia are highly heterogeneous in nature.
- Trial name
- CATChES (NCT01928602)
- Testing
- TherAppy Language App, Mind-Games
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Perinatal Stroke
Parent Therapist Partnership to Provide Early, Intensive Exercise in Perinatal Stroke
A prospective, single blind, parallel group, randomized control trial to determine if early, intensive lower extremity activity delivered by a physical therapist and a parent in partnership improves gross motor function more than…
- Trial name
- NCT03672864
- Testing
- Intensive exercise
- Where
- 3 sites in Canada
- Volunteers
- 18 people
- Sponsor
- University of Alberta
Stroke, Stroke Rehabilitation
Personalised Health Motor and Cognitive Assistance System for RehAbilitation (PHRASE)
This study is a multicentric randomized controlled trial evaluating the effectiveness of digital technology, specifically a smartphone with integrated VR-and AR-based intervention, for at-home rehabilitation after stroke.
- Conditions
- Stroke, Stroke Rehabilitation, Chronic Stroke Patients, Post Stroke Recovery
- Trial name
- PHRASE-2024 (NCT06885502)
- Testing
- RGS
- Where
- 2 sites in Romania, Spain
- Volunteers
- 70 people
- Sponsor
- Eodyne Systems SL
Stroke, Hemiplegic Shoulder Pain
Focal Vibration Therapy in Post-stroke Shoulder Pain
Hemiplegic Shoulder Pain (HSP) is a common and disabling complication after stroke, negatively affecting upper limb function, participation in rehabilitation, and quality of life.
- Conditions
- Stroke, Hemiplegic Shoulder Pain, Chronic Stroke Survivors
- Trial name
- VIBRA-HSP (NCT07513753)
- Testing
- Multimodal Focal Vibration Therapy (FVT), Standard Rehabilitation Program
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Foggia
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