Clinical trials: Taste Disorders
Obesity
Quantitative Evaluation of Bitter Taste in Obesity
Although taste influences food choices and favours diseases like obesity, there is no consensus about the existence of correlations between bitterness and anthropometric variables.
- Trial name
- NCT03149666
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gestational Diabetes Mellitus
Comparing the Effects of Water Temperature and Actives in Glucose Solution on Pregnant Women
To assess the effect of water temperature and additives on pregnant women's taste and side effect during the oral glucose tolerance test (OGTT) evaluation.
- Trial name
- NCT05508425
- Testing
- oral glucose tolerance test using water at room temperature, oral glucose tolerance test using hot water, oral glucose tolerance test using cold water
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chiayi Christian Hospital
Obesity
The Obese Taste Bud Study
The sense of taste is essential for priming food preferences and is therefore important for caloric uptake and body weight regulation.
- Trial name
- OTB (NCT04633109)
- Testing
- taste bud biopsy, oral glucose tolerance test, Taste sensitivity
- Where
- Germany
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Teeth Staining, Numbness of the Tongue and Soft Tissue
Children Acceptance of AgNP Mouthwash Against Chlorhexidine 0.12% and Chlorhexidine .2% Mouthwashs
This study aims to evaluate and compare the children's acceptance of mouthwash containing silver nanoparticles versus Chlorhexidine 0.12% \& Chlorhexidine 0.2%
- Conditions
- Teeth Staining, Numbness of the Tongue and Soft Tissue, Bitter Taste
- Trial name
- NCT07200063
- Testing
- nano silver mouthwash, Chlorhexidine mouthwash (0.12%), Chlorhexidine mouthwash (0.2%)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Cairo University
Smell Dysfunction, Taste Disorders
The Study of Quadruple Therapy Intranasal Insulin, Zinc, Gabapentin, Ice Cube Stimulation for Post COVID-19 Smell and Taste Dysfunctions
post covid-19 smell and taste dysfunction are common globally and affect the quality of life and also have phycological impact and anxiety, also affect on economy as the patients not able to do cooking or buy prepared foods and…
- Conditions
- Smell Dysfunction, Taste Disorders, Taste Disorder, Secondary, Sweet, Taste Disorder, Secondary, Bitter
- Trial name
- COVID-19 (NCT05104424)
- Testing
- Insulin aspart
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
Chewing Problem, Mastication Disorder
Masticatory Side-switch and Mixing Ability.
The main aim of this cross-over intervention study is to assess the effect of masticatory side-switch frequency on different aspects of masticatory function, including masticatory mixing ability and rhythm.
- Trial name
- NCT05173259
- Testing
- F, R, L
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Obesity
CD36 and Human Fat Taste Perception
The purpose of this study is to determine the effect of common human variants in in taste related genes, such as CD36 gene, a putative fat taste receptor, affect fat taste perception.
- Trial name
- FATYP (NCT02699567)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Taste Perception, Saliva Production
Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions
To determine the effect of flavored, carbonated drinks on salivary flow rate, saliva composition, and taste perceptions compared with control drinks (water, carbonated water, non-carbonated)
- Trial name
- NCT06933290
- Testing
- Beverage
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
SARS-CoV Infection, COVID-19
Malaysian COVID-19 Anosmia Study (Phase 2) - A Nationwide Multicentre Case-Control Study
The Malaysian COVID-19 Anosmia Study is a nationwide multicentre observational study to investigate the prevalence and characteristics of olfactory and gustatory/taste disturbances in COVID-19 infection in Malaysia, and to…
- Conditions
- SARS-CoV Infection, COVID-19, Anosmia, Dysgeusia
- Trial name
- NCT04384042
- Testing
- Patient-Reported Online Questionnaire on Olfactory & Taste Disturbances
- Where
- 14 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Sultanah Bahiyah
Taste Disorders, Sensation Disorders
GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers
This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence. This is a descriptive and exploratory study in healthy volunteers.
- Conditions
- Taste Disorders, Sensation Disorders, Taste, Metallic, Taste Disorder, Glossopharyngeal Nerve
- Trial name
- NCT05227157
- Testing
- swab with iron sulfate solution
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Valence
Appetite, Taste, Altered
Impact of Acute Resistance Exercise on Taste Perception and Appetite Response to Plant Protein in Resistance Trained Adults
Some evidence suggests that taste perception might be modulated by physical exercise, with differences observed after aerobic exercise (DOI:10.1093/chemse/23.4.417) and with habitual exercise (DOI:10.3390/nu11010155).
- Conditions
- Appetite, Taste, Altered, Exercise
- Trial name
- NCT06089993
- Testing
- Exercise, Rest
- Where
- Ireland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Obesity
Interactions of Human Gut Microbiota With Intestinal Sweet Taste Receptors
The purpose of this study is to collect data to examine whether short-term consumption of non-caloric artificial sweeteners (NCASs), such as saccharin, can lead to changes in blood sugar levels and in the composition of the…
- Trial name
- ISTAR-micro (NCT03032640)
- Testing
- Oral Glucose Tolerance Test (OGTT), Assessment of dietary compliance, Stool sampling
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
HIV Infections
Taste Properties of HIV Inhibitor
The purpose of the study is to assess the taste properties of HIV inhibitor
- Trial name
- NCT02608918
- Testing
- BMS-955176
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Eating Disorders
Evaluating the Brain's Response to Natural Versus Artificial Sweetener in Women Who Have Had an Eating Disorder
This study will compare the brain's ability to distinguish between natural and artificial sweeteners in women with and without a history of eating disorders.
- Trial name
- NCT00517335
- Testing
- Functional magnetic resonance imaging (fMRI) scan
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Type 1 Diabetes (T1D), Healthy Subjects
Effect of Artificial Sweetener (AFS) on Glucose Metabolism in Patients With Type 1 Diabetes (T1D)
The goal of this randomized crossover study is to test the prediction that consuming carbohydrates will affect insulin release differently depending on whether Non-Nutritive Sweeteners (NNSs) are consumed simultaneously.
- Trial name
- AFS_T1D (NCT06315725)
- Testing
- Sweet taste perception with/without sweet taste blockade
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Testicular Cancer
Taste, Smell and Chemotherapy (TASTY)
Taste and smell abnormalities are common in cancer patients undergoing chemotherapy, with a prevalence ranging from 46% to 77% for taste changes, and 35% to 75% for smell changes.
- Trial name
- TASTY (NCT01641172)
- Testing
- Dexa scan, audiogram, measurement of heart rate variability and baroreflex sensitivity
- Where
- Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Dental Plaque
Efficacy of Two Commercially Available Chlorhexidine Mouthrinses Non-alcohol Base
The purpose of this study was to compare the antiplaque efficacy of a 0,12% chlorhexidine and 0,05% cetyl-pyridinium chloride mouth rinse (Perio-aid®) with a 0,2% chlorhexidine non-alcohol base mouth rinse (Corsodyl Care®).
- Trial name
- NCT01580943
- Testing
- Chlorhexidine
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Ovulation, Menstruation
Impact of Menstrual Phase on Oral Glucose Sensitivity
In this study we are determining whether the hormones associated with the phases of the menstrual cycle (menstruation \& ovulation) influence taste sensitivity to glucose.
- Trial name
- NCT06800690
- Testing
- Urinary Estrogen Level
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Eating Disorders
Determining the Response to Sipping Beverages Without Swallowing in People With Eating Disorders
This study will use a sipping and spitting exercise to better understand the brain's response to food intake in people with eating disorders.
- Trial name
- NCT00353548
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Mental Disorders
Study to Compare Two Formulations of Lamotrigine in Healthy Subjects
This study intends to compare the pharmacokinetic characteristics, safety and tolerability of two formulations of lamotrigine in healthy male and female volunteers
- Trial name
- NCT00410371
- Testing
- Lamotrigine, GI267119
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline