Clinical trials: Terminally Ill
End Stage Cancer
An Interactive Advance Care Planning Intervention to Facilitate a Good Death for Cancer Patients
The purpose of this 5-year interventional study is to design, implement, and evaluate the effectiveness of an intervention aimed at facilitating prognosis communication and end-of-life care decision-making to increase the extent…
- Trial name
- NCT01912846
- Testing
- Interactive advance care planning, Attention usual care
- Where
- Taiwan
- Volunteers
- 466 people
- Sponsor
- Chang Gung University
Constipation, Palliative Care
Effectiveness of Docusate in Preventing/Treating Constipation in Palliative Care Patients
The purpose of this study is to determine if docusate is effective in the treatment of constipation in palliative care patients.
- Trial name
- NCT00902031
- Testing
- Docusate Sodium, Sennoside
- Where
- 3 sites in Canada
- Volunteers
- 70 people
- Sponsor
- University of Alberta
Mental Health Issue
Mandala Intervention on Mental Distress in Nurses Working With Terminally Ill Patients
Mandala application intervention of mental distress in nurses working with terminally ill patients
- Trial name
- mandala (NCT05444010)
- Testing
- mandala painting
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Question Prompt List, Caregivers
The Effectiveness of Using a Palliative Care QPL on the Selfefficacy and Preparedness of Indonesian Homecare Workers
Foreign studies on caregivers' use of QPL in end-of-life care, decision-making, and satisfaction are mostly conducted with family members who share the same language.
- Conditions
- Question Prompt List, Caregivers, End-of-life Care
- Trial name
- NCT06847828
- Testing
- QPL
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Den,Yu-Yun
Cancer
Non-invasive Ventilation in Terminally Ill Cancer Patients
The occurrence of acute respiratory failure (ARF) is often seen by oncologists as a terminal phase of the disease, this view being based on studies reporting limited survival at considerable costs in such patients.
- Trial name
- NCT00533143
- Testing
- non invasive ventilation (NIV)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
End-Of-Life
A Culturally Specific End-of-life Communication Skills Training
The goal of this clinical trial is to evaluate the effectiveness of culturally specific end-of-life communication skills training (CST) among Chinese oncology nurses.
- Trial name
- NCT05888480
- Testing
- The end-of-life communication skills training, Routine training activity
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Ketamine, Refractory Cancer Pain
Continuous IntraVenous Infusion of Ketamine in Terminally Ill Cancer Patients
To establish the role of ketamine in hospitalized terminally ill cancer patients with refractory cancer pain, using continuous intravenous infusion of ketamine
- Trial name
- CIVIK (NCT03362073)
- Testing
- Ketamine
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Pusan National University Yangsan Hospital
Dementia, Alzheimer's Disease
A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of [18F]NAV4694 PET for Detection of Cerebral Beta-Amyloid When Compared With Postmortem Histopathology
To Determine the the Efficacy and Safety of [18F]NAV4694 PET for Detection of Cerebral β-Amyloid When Compared With Postmortem Histopathology
- Trial name
- NCT01886820
- Testing
- [18F]NAV4694
- Where
- 15 sites in United States
- Volunteers
- 290 people
- Sponsor
- Navidea Biopharmaceuticals
Palliative Care
Randomized Controlled Trial of Group Psychotherapy Interventions for Cancer Patients
The purpose of this study is to compare two types of group counseling for cancer patients: Meaning-Centered counseling and Supportive counseling.
- Trial name
- NCT00494910
- Testing
- Meaning Centered Group Psychotherapy, Supportive Group Psychotherapy
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Advanced Cancer
Measuring Hope and Hopelessness in Cancer
The purpose of this study is to develop an accurate and useful way of measuring patients' thoughts and feelings about hope and hopelessness as they relate to their illness.
- Trial name
- NCT00581880
- Testing
- questionnaires
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Communication, Palliative Sedation
REcommened Communication With Sympathy in Terminally Ill Cancer Patients Treated With Palliative Sedation
In terminally ill cancer patients, palliative sedation has been applied to intractable refractory symptoms such as pain, dyspnea, delirium, agitation.
- Trial name
- RESTORE (NCT04642677)
- Testing
- healthcare provider's recommended communication with sympathy and printed paper
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Pusan National University Yangsan Hospital
Terminally Ill
End-of-life Communication From a Chinese Perspective
The goal of this observational study is to explore experiences and perceptions of end-of-life communication in Chinese terminally ill patients, families and healthcare providers.
- Trial name
- NCT05734781
- Testing
- Not Application as this is a qualitative study
- Where
- China
- Volunteers
- 66 people
- Sponsor
- The Hong Kong Polytechnic University
Chronic Myeloproliferative Disorders, Leukemia
Treatment for Chronic Pain in Patients With Advanced Cancer
RATIONALE: Different drug formulations and combinations of drugs may help patients with chronic pain live more comfortably. It is not yet known which regimen is most effective for chronic pain.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00003687
- Testing
- dextromethorphan hydrobromide, morphine sulfate
- Where
- 4 sites in Canada
- Volunteers
- 87 people
- Sponsor
- NCIC Clinical Trials Group
Refractory Pains
Efficiency and Safety of a Procedural Sedation by Propofol on Terminally Ill Patients With Refractory Pain
Relieving symptoms of patients hospitalized in a palliative care unit is a priority. Although they receive appropriate care, they may still experience pain refractory to analgesia or/and to conservative treatment during care…
- Trial name
- PROPOPAL2 (NCT02734511)
- Testing
- sedation with propofol
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pain
Marijuana in Combination With Opioids in Palliative and Hospice Patients
Study Objectives: Primary reduction of pain and reduction in overall opioid utilization. Secondary improvement in overall patient well being, weight stabilization with increased appetite, improved oxygen saturation, improvement…
- Trial name
- NCT03233633
- Testing
- Medical Marijuana
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- The Connecticut Hospice Inc.
Xerostomia, Salivary Gland Diseases
Efficacy Study of a Ginger and Cardamom Gelatin for Xerostomy in Terminally Ill Patients
Xerostomia or dry mouth is the subjective feeling that there is not enough saliva in your mouth. It's a frequent symptom in terminally ill patients receiving palliative care, reducing their quality of life and comfort.
- Conditions
- Xerostomia, Salivary Gland Diseases, Mouth Diseases
- Trial name
- NCT01915966
- Testing
- Cardamom, ginger and orange juice gelatin, Camomile infusion with lemon juice
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Fundacio Salut i Envelliment UAB
Peripherally Inserted Central Catheter, Intravenous Access
Comparison Between Initial Routine PICC and General IV Access in Terminally Ill Cancer Patients
To establish the IV access strategy for terminally ill cancer patients, using comparisons of the safety, efficacy, and patient-perceived satisfaction between the initially routine PICC insertion group (routine PICC group) and…
- Trial name
- NCT03299868
- Testing
- peripherally inserted central catheter (PICC)
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Pusan National University Yangsan Hospital
Nausea, Vomiting
Palonosetron for the Treatment of Nausea and Vomiting in Terminally Ill Patients
The primary objective of this study is to determine the complete response (no vomiting and no need for other medications to treat nausea) in terminally ill patients suffering from nausea and/or vomiting, who are treated with…
- Conditions
- Nausea, Vomiting, Terminally Ill
- Trial name
- HUM21469 (NCT00982995)
- Testing
- Palonosetron
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Michigan Rogel Cancer Center
Emotional Stress, Psychological Distress
Dignity Therapy for Terminally Ill Patients: A Randomized Controlled Trial
We conducted a randomized, controlled trial of dignity therapy for terminally ill patients with the aim of reducing dignity-related distress and demoralization and improving spiritual well-being.
- Conditions
- Emotional Stress, Psychological Distress, Death, Dignity
- Trial name
- NCT04256239
- Testing
- Dignity Therapy
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- European University of Rome
Assisted Dying, Palliative Care
Palliative Care and The Terminally Ill Adults (End of Life) Bill
The current study aims to investigate the potential impact of the proposed Assisted Dying (Terminally Ill Adults (2024) Bill on Palliative care workers.
- Trial name
- NCT07427550
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust