Clinical trials: Unintentional Injury
Hemorrhagic Shock, Trauma Injury
Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children
The MATIC-2 is a multicenter clinical trial enrolling children who are less than 18 years of age with hemorrhagic shock potentially needing significant blood transfusion.
- Trial name
- MATIC-2 (NCT06070350)
- Testing
- Low Titer Group O Whole Blood (LTOWB), Tranexamic Acid (TXA), Component Therapy (CT)
- Where
- 23 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Philip Spinella
Hemorrhagic Shock, Trauma Injury
California Prehospital and In Hospital Antifibrinolytic Therapy Via TXA
The California Prehospital Antifibrinolytic Therapy (Cal-PAT) study seeks to evaluate the safety and efficacy of Tranexamic Acid (TXA) use in the civilian prehospital and in hospital setting in cases of traumatic hemorrhagic…
- Trial name
- Cal-PAT (NCT03469947)
- Testing
- Tranexamic Acid
- Volunteers
- 200 people
- Sponsor
- Arrowhead Regional Medical Center
Trauma Centers, Trauma Patients
Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) as an Adjunct to Standard Treatment According to National Guidelines in the National Trauma Plan Among Adult Trauma Patients in Norway.
The POSTRAUMA trial is a clinical trial at The Regional trauma centre of Western Norway, Haukeland University Hospital. Trauma is the leading cause of death worldwide in patients aged 1-45 years.
- Conditions
- Trauma Centers, Trauma Patients, Trauma (Including Fractures), Trauma Injury
- Trial name
- POSTRAUMA (NCT07268716)
- Testing
- The intervention is a tailored patient Information and Patient-managed Outpatient Digital follow-up treatment
- Where
- Norway
- Volunteers
- 256 people
- Sponsor
- Haukeland University Hospital
Trauma Injury, War Injury
Surgery in Context of Terrorist Attack : a Survey of French Surgeons
The aim of the study is to assess the surgical knowledge of French Surgeons in cas of Terrorist Attack.
- Conditions
- Trauma Injury, War Injury, Surgical Procedure, Unspecified
- Trial name
- NCT04327895
- Testing
- evaluation of the need for training
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Trauma Injury, Child, Only
Using mHealth to Improve Emotional Recovery After Pediatric Injury
Nearly 300,000 U.S. children experience injuries that require them to be hospitalized this year. These children, and their caregivers, are at high risk for emotional and behavioral problems, as well as poor quality of life.
- Conditions
- Trauma Injury, Child, Only, Posttraumatic Stress Disorder, Parents
- Trial name
- NCT04579198
- Testing
- Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Critical Illness, Heart Failure
Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress
Serious acute heart and lung illnesses like heart failure, severe COVID, and sepsis often leave survivors struggling not only physically, but also with lasting depression, anxiety, and stress.
- Conditions
- Critical Illness, Heart Failure, Sepsis, Ards
- Trial name
- Lift 3 (NCT07634419)
- Testing
- Lift mobile mindfulness, Enlighten Recovery education program
- Where
- 3 sites in United States
- Volunteers
- 450 people
- Sponsor
- Duke University
Trauma Injury, Mortality Prediction
Fall Injury Mortality Prediction
This retrospective, multicenter, registry-based cohort study used data from the Pan-Asian Trauma Outcomes Study registry between January 2016 and December 2024.
- Conditions
- Trauma Injury, Mortality Prediction, Fall
- Trial name
- NCT07643051
- Testing
- Prediction model development
- Volunteers
- 58,353 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Amyotrophic Lateral Sclerosis, Muscular Dystrophy
Innovative Ultrasound Technology in Neuromuscular Disease
This study is utilizing ultrasound measurement to measure neuromuscular disease status in adult patients. The hypothesis is the by quantifying ultrasound data, it is possible that ultrasound can be utilized as a tool to determine…
- Conditions
- Amyotrophic Lateral Sclerosis, Muscular Dystrophy, Radiculopathy, Myopathy
- Trial name
- AQUIRe (NCT02104921)
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Trauma Injury, Thromboembolism
Antithrombin to Improve Thromboprophylaxis and Reduce the Incidence of Trauma-Related Venous Thromboembolism
The purpose of this study is to determine if additional interventions will assist with decreasing the risk and/or severity of thromboembolism (clotting complications) in patients who have experienced a major traumatic event.
- Conditions
- Trauma Injury, Thromboembolism, Venous Thromboembolism
- Trial name
- TRAIT (NCT05794165)
- Testing
- Thrombate infusion
- Where
- 5 sites in United States
- Volunteers
- 314 people
- Sponsor
- Bryan Cotton
Trauma Injury
Retrospective Assessment of Referral of a Major Trauma Patient
The aim of this study is to find out whether major trauma patients from the Val d'Oise are referred to the appropriate trauma centre for their care and to assess the quality of triage within the Val d'Oise department.
- Trial name
- SAMU-TRAUMAS (NCT06551350)
- Testing
- Data Collection
- Where
- France
- Volunteers
- 461 people
- Sponsor
- Hôpital NOVO
Trauma Injury, Coagulopathy
Predictive Accuracy of PLR and PNR in Detecting ETIC
Observational study to know what is the predictive accuracy of platelet-neutrophil ratio (PNR) and platelet-lymphocyte ratio (PLR) done in patients presenting to ED( emergency department)within 6 hours of trauma; in detecting…
- Trial name
- ETIC (NCT07046858)
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Trauma Injury, Child Behavior
Injury Prevention Model For K-1 Students
There is no educational injury prevention model uniquely suited for kindergarten and first grade (K-1) students. The Teddy Bear Injury Clinic (TBIC) is a unique modification of the teddy bear clinic to facilitate classroom injury…
- Trial name
- NCT05944315
- Testing
- Education session
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Good Samaritan Hospital Medical Center, New York
Trauma Injury
SFDI in High Energy Lower Extremity Fracture
This is a non-randomized prospective study of 20 patients with high energy lower extremity fractures evaluating feasibility and acceptability of SFDI, a real-time optical imaging technology.
- Trial name
- NCT05635617
- Testing
- Lower Extremity Surgery
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Occult Bleeding, Hemorrhage
Trauma Study: Early Warning of Progression Toward Hemodynamic Deterioration After Trauma
This study is Phase 3 of a three-phase DOD CDMRP funded project for the development of a multi-technology poly-anatomic noninvasive system for early detection of occult hemorrhage.
- Trial name
- NCT04912232
- Testing
- Detection of Occult Hemorrhage in Trauma Patients
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Trauma Injury, Hemorrhage Wound
Assessment of Automatic Tourniquets for Soldiers During Wartime
The goal of this clinical trial is to compare usability and performance of automatic tourniquets (AUT) and standard mechanical tourniquets (CAT) in healthy adults.
- Trial name
- NCT06123104
- Testing
- Occlusion of blood flow diagnosed by Point of Care UltraSound (POCUS)
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Cutaneous Ulcer, Trauma Injury
Reconstruction of Skin Substance Loss With "Micro-grafts" Obtained by Mechanical Disintegration
The etiology of non-healing ulcers depends on both systemic and local factors. The introduction of advanced dressing, negative wound therapy and compression therapy have undoubtedly improved clinical outcomes.
- Trial name
- MG-1 (NCT04030832)
- Where
- 4 sites in Italy
- Volunteers
- 70 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Trauma Injury, Maxilla Fracture
Prospective Study to Evaluate the Performance and the Safety of Global D's Implants of Craniomaxillofacial Surgery (CMF) Ranges Indicated for Trauma Surgery
This study is set up within the framework of the European Union regulation 2017/745 on medical devices. Its objective is to confirm the performance and safety of the Global D implants (ORTRAUTEK® and MINITEK/MICROTEK®) used for…
- Conditions
- Trauma Injury, Maxilla Fracture, Maxillofacial Trauma
- Trial name
- NCT05742932
- Testing
- Trauma surgery using Global D's implants.
- Where
- 2 sites in France
- Volunteers
- 99 people
- Sponsor
- Global D