Clinical trials: Vaccinations
COVID-19, Vaccine Hesitancy
Online Games to Help Canadian and U.S. Adults Identify COVID-19 and Vaccine Misinformation: Three Sequential Randomized Studies
COVID-19 misinformation contributed to vaccine hesitancy and preventable illness. This record covers three sequential randomized studies (conducted in Canada and the United States, November-December 2020) testing whether a brief…
- Conditions
- COVID-19, Vaccine Hesitancy, Health Misinformation, Communication
- Trial name
- NCT07758309
- Testing
- Gamified misinformation refutation quiz, Refutational text (active control)
- Where
- United States
- Volunteers
- 3,637 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Vaccination
"Facts Tell… and With Stories Sell?" Combining Viewer-tailored Personal Human Papillomavirus (HPV) Narrative Video With HPV Vaccine Information Video to Improve HPV Vaccine Uptake
This study will compare the use of informational videos only, personal story videos only, and the combination of both, to see which is most effective in increasing HPV vaccination.
- Trial name
- NCT06587243
- Testing
- Informational Animation Video, Personal Narrative Video
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
COVID-19, Vaccine Hesitancy
Addressing COVID-19 Vaccine Hesitancy With Muliti-Level Interventions in Appalachia
The purpose of this community-engaged study is to test the ability of county-level strategies to increase uptake of COVID-19 vaccination.
- Trial name
- K-VAC (NCT06505993)
- Testing
- Health Communication, Health Communication + Structural
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Marc Kiviniemi
Immunization Coverage, Vaccination
Increasing Measles Vaccination Coverage Through Supplementation With an SQ-LNS Incentive in Children Aged 6-23 Months
Provision of SQ-LNS also holds promise in incentivizing vaccination as well as other health services. The investigators will estimate 1) the effectiveness of a SQ-LNS mass supplementation program added to routine immunization…
- Conditions
- Immunization Coverage, Vaccination, Nutrition
- Trial name
- NCT06387511
- Testing
- Small-quantity lipid-based nutrition supplements (SQ-LNS) NutriVax, Sensitization on vaccination and on Infant and Young Child Feeding (IYCF) practices
- Where
- Nigeria
- Volunteers
- 3,814 people, healthy volunteers welcome
- Sponsor
- Alliance for International Medical Action
Vaccination Refusal
Improving Vaccinations for Young Children (IVY)
The IVY project focuses on improving combination 10 vaccine rates for Tennessee children through an educational and quality improvement intervention rolled out through a stepped-wedge cluster randomized trial.
- Trial name
- IVY (NCT04203277)
- Testing
- IVY
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Covid19, Vaccine Refusal
COVID-19 Vaccine Education at the Point of Testing to Increase Vaccine Uptake in Vulnerable Communities in SE Louisiana
This project is a 2-year study to investigate vaccine hesitancy and vaccine completion among vulnerable communities in the Southeastern Louisiana region.
- Conditions
- Covid19, Vaccine Refusal, Vaccine Hesitancy
- Trial name
- NCT04939506
- Testing
- COVID-19 Vaccine Education at the Point of COVID-19 Testing
- Where
- United States
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Vaccination Refusal, COVID-19
COVID-19 Vaccine Uptake Trial
The goal of this study is to assess the best COVID-19 vaccine uptake strategy among students, staff and household members that have not been vaccinated.
- Trial name
- NCT05419232
- Testing
- Short Message Service (SMS) + Website Link Strategy, Phone Call with Peer Strategy
- Where
- 8 sites in United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Vaccine Response, COVID-19 Vaccine
Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine
The goal of this research is to learn more about ZADAXIN® (trade name; thymalfasin generic; Ta1 for short) and determine if Ta1 has any benefit in increasing the immune response to the COVID-19 vaccine.
- Conditions
- Vaccine Response, COVID-19 Vaccine, Immune Response to Covid 19 Vaccination
- Trial name
- NCT06821100
- Testing
- Thymalfasin (Thymosin alpha 1, Ta1)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Vaccine Refusal, Vaccine Hesitancy
Predicting Vaccine Hesitancy Using Machine Learning
In recent years, emerging technologies such as the Internet of Things (IoT), Artificial Intelligence (AI), and Virtual Reality (VR) have rapidly become integrated into daily life.
- Conditions
- Vaccine Refusal, Vaccine Hesitancy, Machine Learning, Children
- Trial name
- NCT06988969
- Where
- Turkey (Türkiye)
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Vaccine Hesitancy, Vaccine Refusal
Vaccine Confidence Study Among Historically Marginalized Racial and Ethnic Groups
Achieving optimal vaccination rates is vital for protecting the health and well-being of all individuals. This specific study focuses on the MMR and RSV vaccines in pregnancy and early childhood, which have been shown to reduce…
- Trial name
- NCT06639386
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Vaccination, Vaccination Promotion
ARISe at UMass Chan
The goal is to identify the most impactful strategies for capturing attention and enhancing effectiveness of vaccine promotion messages.
- Trial name
- ARISe (NCT07236034)
- Testing
- Exposure to source and message content
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Tetanus, Diphtheria and Acellular Pertussis Vaccination
Safety and Immunogenicity Study of Tdap Vaccinations for Plasma Donors
The goal of this clinical trial is to investigate the safety and tetanus antibody response to a Tdap vaccine in healthy plasma donors.
- Trial name
- NCT05662852
- Testing
- Tdap
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- ABO Holdings, Inc.
Simulation-based Education, Vaccination Training
High-Fidelity Simulation in Vaccination Training
This study compared the impact of high-fidelity simulation (HFS) versus standart laboratory practice (SLP) on nursing students' knowledge, psychomotor skills, learning satisfaction, and self-confidence within a childhood…
- Conditions
- Simulation-based Education, Vaccination Training, Education Nursing
- Trial name
- NCT07678190
- Testing
- High-Fidelity Simulation, Standard Laboratory Practice
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Vaccination
Evaluation of Immune Response Against the Strain of Neisseria Meningitidis B: 14, P1-7, 16 Patients Have to be Vaccinated MenBVac®
The main objective of the study is to estimate the proportion of children, born between the 06/04/2004 and the 17/004/2008, living around Neufchatel en Bray, vaccinated by MenBVac, with a serum bactericidal activity against…
- Trial name
- EFFIVAC (NCT01054053)
- Testing
- MenBVac Vaccination
- Where
- France
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
HPV-related Cancers, HPV Vaccination
Trial in HPV Prevention for the U.S. Vietnamese Community
The purpose of the HERO study is to leverage the Multiphase Optimization Strategy (MOST) framework to conduct a pilot trial testing four different intervention components (expert video, self-persuasion, narrative storytelling…
- Trial name
- HERO (NCT07637630)
- Testing
- Expert Video, Self-persuasion, Narrative Storytelling
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Northwestern University
HPV, Vaccine Acceptance
Addressing HPV Vaccine Hesitancy by Co-Designing a Digital Health Intervention
This study looks at a digital platform that supports HPV vaccination in schools. The goal is to see if it is useful, easy to use, and practical in real school settings, especially in areas where fewer people get vaccinated.
- Conditions
- HPV, Vaccine Acceptance, Vaccine Decision Making, HPV Vaccination
- Trial name
- HPV-END-IT (NCT07632963)
- Testing
- HPV-Kompassen
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
HPV Vaccination, Uptake Vaccination
PREVENT Pilot HPV - Related Cancers Trial
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Uptake Vaccination, Series Completion
- Trial name
- NCT06738355
- Testing
- PREVENT
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Utah
Vaccination With MenbVac
Evaluation of Immune Response Against the Strain of Neisseria Meningitidis B: 14, P1-7, 16 Patients Vaccinated With MenBVac® (Extension MenbVac)
This study aims to estimate the vaccinal immunity four years after four doses of MenbVac in children aged 4-8 years.
- Trial name
- Exten MenbVac (NCT01565577)
- Testing
- MenbVac
- Where
- France
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
HPV Vaccination, Cancer Prevention
Empowering Vietnamese Americans
The goal of this clinical trial is to learn whether short videos can help Vietnamese American mothers decide to vaccinate their children against HPV (human papillomavirus).
- Trial name
- NCT07164391
- Testing
- Digital Intervention for Vietnamese-American Storytelling (VIDAS), Teen General Health
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Flu-like Syndrome, FLU
Can the Ergometric Test in Flu-like Syndrome Help in the Outcome Analysis of Unvaccinated Patients
During the flu-like syndrome, the cardiovascular risk is increased, especially in the elderly. Understanding whether blood pressure assessment during an exercise test can aid in the understanding of patient outcomes, thereby…
- Conditions
- Flu-like Syndrome, FLU, Flu-like Symptoms, Vaccination
- Trial name
- NCT07007377
- Testing
- Follow-up
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo