Clinical trials: Very Low Calorie Diet
Obesity
Effects of Very Low-calorie Diet Versus Bariatric Surgery on Body Composition and Gut Microbiota Pattern
Obesity is a chronic disease characterized by the excessive accumulation of fat in body and it continues to be a major public health problem worldwide.
- Trial name
- NCT05459675
- Testing
- Very low-calorie diet, Bariatric surgery
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Bariatric Surgery Candidate, Ketogenic Dieting
Ketogenic Diet Prior to Bariatric Surgery
Standard dietary regiments for bariatric are advised prior to surgery. The most used diet is a very low calorie diet (VLCD). These diets potentially have multiple pittfalls.
- Trial name
- NCT06850493
- Testing
- VLCKD (ketogenic diet), VLCD (Very-low-calorie-diet)
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Obesity, Insulin Resistance
Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health
The purpose of this study is to understand how weight loss by a very low fat plant-based diet with an exercise program affects metabolic and cardiovascular health in overweight adults at high risk for disease.
- Trial name
- PE (NCT02706288)
- Testing
- Weight loss with very low fat plant-based diet and regular exercise
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Weight Loss, Inflammation
Effect of Very-low Calorie Diet and Synbiotic Supplementation in Gut Microbiota (Pronokal Method)
The present study aimed to investigate the changes produced in gut microbiota by a very-low-calorie-ketogenic diet followed by a low calorie diet, whether the use of synbiotics is able to modulate gut microbiota diversity and…
- Trial name
- Pronokal (NCT03530501)
- Testing
- Diet, Synbiotic1, Synbiotic2
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Obesity, Morbid Obesity
Long Term Effect of Very-low-calories Ketogenic Diet on Weight Control and Cardiovascular Brisk Factors (KETOHEART)
The growing obesity pandemic has a major impact on global cardiovascular (CVD)-related morbidity and premature mortality, severely compromising the quality of life of those affected and significantly increasing costs for the…
- Trial name
- KETOHEART (NCT05781269)
- Testing
- VLCKD, r-MedDiet
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Obstructive Sleep Apnea
Effect of a Very Low Calorie and Low Calorie Diet on Moderate to Severe Obstructive Sleep Apnea in Obese Adults
The purpose of this study is to test the effectiveness of two different weight loss diets on obstructive sleep apnea (OSA) severity.
- Trial name
- NCT02251574
- Testing
- Low Calorie Diet, Very Low Calorie Diet, Standard Care
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Bariatric Surgery Candidate
Compliance With Standard Care vs Ready to Eat Meals Prior to Bariatric Surgery
Currently, a ketosis-inducing programme, usually a liquid meal replacement, is the standard of care for pre-operative dietary management.
- Trial name
- NCT06461247
- Testing
- Very Low Calorie Diet Ready-to-eat (VLCD RTE) meals, Standard Care Group
- Where
- 2 sites in Singapore
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Obesity
Very Low Calorie Ketogenic Low-fat Diet (VLCKLFD)
This study aimed to assess the efficacy and safety of the Zélé program, a controlled ketogenic diet, for weight loss and maintenance.
- Trial name
- Zelé2021 (NCT06275347)
- Testing
- Low-fat normoprotein Controlled Ketogenic Diet., Hypocaloric Balanced Diet
- Where
- Mexico
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Universidad Veracruzana
Obesity
Combined Effects of GLP-1 Analogue and Exercise on Maintenance of Weight Loss and Health After Very-low Calorie Diet
Introduction: The success rate of weight loss maintenance is limited. Therefore, the purpose of this study is to investigate the maintenance of weight loss and immunometabolic health outcomes after diet-induced weight loss…
- Trial name
- S-LITE (NCT04122716)
- Testing
- Liraglutide, Exercise
- Where
- Denmark
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Signe Torekov
Rectal Cancer, Obesity
Preoperative Very Low Energy Diet for Obese Rectal Cancer Patients
This pilot study will aim to determine the feasibility, safety, and cost associated with a preoperative VLED for obese rectal cancer patients.
- Trial name
- NCT04379830
- Testing
- Very Low Energy Diet
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Morbid Obesity
Utilization of Very Low Calorie Diet in Obese General Surgery Patients
The investigators are studying the use of a two-week very low calorie diet (VLCD) in obese general surgery patients in a randomized single-blinded trial.
- Trial name
- NCT03553849
- Testing
- Very low calorie diet
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Obesity
Effects of Leptin Treatment on Weight Loss
This is a double blind placebo controlled clinical study designed to determine the effects of leptin on the changes that occur in the body during weight loss achieved by a very low calorie diet.
- Trial name
- NCT00050791
- Testing
- Leptin, Very Low Calorie Diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Overweight and Obesity
The Effect of Very Low Calorie Diet With and Without Exercise on Muscle Synthesis in Middle-aged Overweight Male.
The aims of this project are: to investigate the impact of VLCD on control of muscle protein synthesis, muscle structure and function, cardiac function (ejection fraction), vascular function (blood flow and capillary function)…
- Trial name
- VLCDex (NCT03116256)
- Testing
- Very low calorie diet (VLCD), High intensity interval training (HIIT), Resistance exercise training (RET)
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Healthy
Effects of Dihydrocapsiate on Adaptive and Diet-Induced Thermogenesis With a High Protein Very Low Calorie Diet
The study is designed to determine the effects of a non-pungent supplement from sweet chilli pepper on resting metabolic rate and diet-induced thermogenesis (DIT) after a period of very low calorie intake over 4 weeks.
- Trial name
- NCT01142687
- Testing
- dihydrocapsiate capsule
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obesity
The Effect of a Short-term Very Low Calorie Diet on Heart Rate Variability in Obese Individuals
The purpose of this study is to determine whether short-term adherence to a very low calorie diet is effective in improving heart rate variability in obese individuals.
- Trial name
- NCT02070770
- Testing
- Very low calorie diet, Standard weight loss diet
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy
Very Low-calorie Diet & Cardiometabolic Health
To investigate the effects of a short-term (1-week) nutritional intervention in healthy individuals using very low-calorie (fasting-mimicking) diets with different protein content on markers of cardiometabolic health and…
- Trial name
- NCT06560996
- Testing
- Very low calorie diet with low protein content (VLCD-LP group), Very low calorie diet with high protein content (VLCD-HP group)
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
HCG
Muscle-Sparing Effect Of Human Chorionic Gonadotropin (hCG) During a Very Low Calorie Diet (VLCD)
Subjects are female patients, randomized to HCG group or placebo group, during a prospective trial, in order to determine the significance, if any, of HCG on maintaining muscle mass during a very low calorie diet in order to…
- Trial name
- NCT02427529
- Testing
- Human Chorionic Gonadotropin, Low calorie diet
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Dr. Emma's Corporation
Morbid Obesity, Steatosis
Very Low Calorie Liquid Diet for Pre op Patients
Despite the relative consensus on the benefits of pre-surgical weight loss, i.e., the reduction of comorbidities associated with surgical act, such as decreased visceral fat, liver volume, hemorrhage perioperative and surgical…
- Trial name
- NCT01748682
- Testing
- A very low calorie diet of two different consistencies
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Silvia Leite Faria