Clinical trials: Water-Related Diseases
Dehydration, Dehydration Related to Exercise
The Impact of a Caffeinated Sports Drink on Performance
Caffeine is known to enhance physical and mental performance, but few beverages combine caffeine with electrolytes and carbohydrates to enhance exercise performance.
- Trial name
- NRG (NCT06721793)
- Testing
- carbohydrate electrolyte drink, no-sugar electrolyte drink, Caffeinated Carbohydrate and electrolyte drink
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose…
- Conditions
- Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension
- Trial name
- POPS or POP02 (NCT04278404)
- Testing
- The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Water-Related Diseases, Gastrointestinal Diseases
Canadian Beach Cohort Study
Swimming and other water activities at public beaches are increasingly popular leisure activities among Canadians. However, these activities can lead to increased risks of acquiring acute gastrointestinal illness and respiratory…
- Trial name
- NCT06413485
- Testing
- Level of recreational water contact activities
- Where
- 5 sites in Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Dehydration, Advanced Cancers
Physician Perceptions About Parenteral Hydration in Latin America and Spain
The purpose of this study is to assess palliative care physicians' attitudes, beliefs and practice patterns related to parenteral hydration at the end of life in Latin America and Spain. Objectives: 1.
- Trial name
- NCT01011140
- Testing
- Survey
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Dehydration Related to Exercise
Rehydration Following Exercise-Induced Dehydration
Athletes participating in multiple training sessions a day can be at increased risk of suboptimal hydration and heat illness during their second training session, especially when the environment is hot and humid.
- Trial name
- NCT01974986
- Testing
- Water with flavoring and non-nutritive sweetener., High-Na low-CHO beverage, Low-Na high-CHO beverage
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Menopause, Menopause Related Conditions
Hot Water Therapy for the Treatment of Menopause-related Hot Flashes
The purpose of this research is to determine whether hot water therapy (i.e. taking prolonged hot baths on multiple consecutive days) decreases hot flash symptoms and improves mood in women who are undergoing or who have…
- Conditions
- Menopause, Menopause Related Conditions, Menopause Syndrome
- Trial name
- NCT06192329
- Testing
- Hot water therapy, Warm water immersion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Hyperkalemia
Relationship Between Potassium Level in Venous Blood Samples Drawn and Heel Sticks In Infants and Newborns
The purpose of this study is to find out whether there is a correlation (link) between the level of potassium in blood samples drawn from a vein and those drawn from a heel stick in infants scheduled for elective surgery.
- Trial name
- PS (NCT01349218)
- Testing
- Blood sample drawn from a vein, Blood sample drawn from a heel stick
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Obesity, Water; Lack of
Preventing Early Childhood Obesity, Part 1: Family Spirit Nurture, 3-9 Months
This study aims to assess the impact of a brief home-visiting module, called "Family Spirit Nurture" (FSN), on American Indian (AI) parent feeding practices associated with increased risk for early childhood obesity, with a…
- Conditions
- Obesity, Water; Lack of, Breast Feeding, Tooth Erosion
- Trial name
- NCT03101943
- Testing
- Family Spirit Nurture (FSN), Control Program, Water Delivery
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Water-Related Diseases, Enteric Pathogens
Rural Appalachia Pilot Water Treatment Trial
Consumption of unsafe drinking water is associated with a substantial burden of disease globally. In the USA, the burden of disease associated with consumption of contaminated drinking water from non-regulated private wells and…
- Conditions
- Water-Related Diseases, Enteric Pathogens, Exposure to Chemical Pollution
- Trial name
- NCT06120985
- Testing
- Countertop pitcher water filter
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Abdominal Pain
Heart Rate Variability in Children With a Functional Gastrointestinal Disorder
The current study is designed to assess relationships between anxiety/stress, autonomic nervous system balance, and electrical activity in the stomach before and after eating/drinking in children with abdominal pain.
- Trial name
- NCT00195975
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Autonomic Nervous System Diseases, Baroreflex Failure
Effects of Water and Glucose Drinks on Cardiovascular Function in Subjects With and Without Postprandial Hypotension
To determine whether the changes in blood pressure (BP) which occur following meals in normal people and patients who have substantial falls in BP after a meal postprandial hypotension (PPH)) are associated with changes in…
- Conditions
- Autonomic Nervous System Diseases, Baroreflex Failure, Blood Pressure, Hypotension
- Trial name
- NCT02713412
- Testing
- Glucose, Water
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Royal Adelaide Hospital
Postpartum Hemorrhage, Pregnancy Related
Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in Parturients
Calcium is a life saving medicine in the care of parturients. It has many important uses including treatment of hypocalcemia, treatment of magnesium toxicity, prevention of hypocalcemia during blood transfusion (of citrate…
- Conditions
- Postpartum Hemorrhage, Pregnancy Related, Hypocalcemia, Parturition Complication
- Trial name
- NCT05973747
- Testing
- Calcium Gluconate, Calcium chloride
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Stanford University
Nutrition Poor, Aflatoxins Toxicity
One Nutrition in Complex Environments (ONCE)
This study asks the research question "Does enabling families (particularly mothers and other caregivers) to 'assess and act' on drivers of malnutrition through a targeted SBC+ package succeed in a sustained reduction of risk…
- Conditions
- Nutrition Poor, Aflatoxins Toxicity, Water-Related Diseases
- Trial name
- ONCE (NCT04209569)
- Testing
- Nutrition Impact and Positive Practice Circle (NIPP)
- Where
- Uganda
- Volunteers
- 1,834 people, healthy volunteers welcome
- Sponsor
- Tufts University
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Aging
Aquatic Exercises Combined With Cognitive Tasks for Older Adults
The aquatic environment has characteristics that favor the adherence of older adults to exercise programs, and studies have shown that programs in this setting are effective in enhancing various aspects of physical fitness as…
- Trial name
- WaterCog (NCT07156708)
- Testing
- Aquatic aerobic exercise program, Cognitive tasks
- Where
- Brazil
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Chronic Pain
The Effects of Water Temperature on the Cold Pressor Test
This current study is intended to be completed under the umbrella of the current GHUCCTS IRB- approved study "Opioid-Induced Hyperalgesia In Prescription Opioid Abusers: Effects of Pregabalin" (Lyrica study) (PRO00000669).
- Trial name
- NCT03083626
- Testing
- Cold pressor test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgetown University