Clinical trials: completed, in Pakistan
Work-related Neck Pain
Scapular Muscle Strengthening Combined With Core Stabilization Exercises in Telephone Operators With Neck Pain
Scapular muscle strengthening combined with core stabilization exercises is an effective intervention for reducing neck pain in telephone operators.
- Trial name
- NCT07480772
- Testing
- Scapular + Deep Cervical Muscle Strengthening, Deep Cervical Muscle Strengthening
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- University of Lahore
Colorectal Diseases, Intestinal Diseases
Early Versus Delayed Ileostomy Closure Following Bowel Surgery
Temporary ileostomy is commonly created following bowel surgery to protect distal anastomoses and reduce the consequences of anastomotic leakage. However, the optimal timing for ileostomy closure remains controversial.
- Conditions
- Colorectal Diseases, Intestinal Diseases, Ileostomy
- Trial name
- EDIC (NCT07754227)
- Testing
- Early Ileostomy Closure, Delayed Ileostomy Closure
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Dr. Waseem Ullah
Preterm Infants, Neonatal Respiratory Distress Syndrome
Comparison of the Need Of Mechanical Ventilation Between Less Invasive Surfactant Administration (LISA) and Conventional INSURE (Intubation-Surfactant Administration-Extubation) Methods in Spontaneously Breathing Preterm Infants With Respiratory Distress Syndrome
Brief Summary of the Study This randomized controlled trial aims to compare the need for mechanical ventilation between Less Invasive Surfactant Administration (LISA) and the conventional INSURE (Intubation, Surfactant…
- Conditions
- Preterm Infants, Neonatal Respiratory Distress Syndrome, Need for Mechanical Ventilation
- Trial name
- NCT07910539
- Testing
- Intervention Name: Poractant alfa (surfactant) administered by the INSURE method
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Fatima Jinnah Medical University
Ankle Fractures, Joint Stiffness
Virtual Reality-Integrated Rehabilitation Versus Conventional Balance Therapy Following Ankle Fracture
This study compares virtual reality-based balance training with conventional balance therapy in adults recovering from an ankle fracture after a period of immobilization.
- Conditions
- Ankle Fractures, Joint Stiffness, Postural Balance, Proprioception, Postural Balance
- Trial name
- NCT07906002
- Testing
- Virtual Reality Balance System (VR-Training), Standard Physical Therapy (Conventional Exercise)
- Where
- 2 sites in Pakistan
- Volunteers
- 22 people
- Sponsor
- Dr Aneeqa Sultan
Guillain-Barré Syndrome, Neuropathic Pain
Comparison Between Efficacy of Gabapentin and Carbamazepine in Neuropathic Pain of Guillain-Barré Syndrome Patients
This randomized controlled trial compared gabapentin with carbamazepine for the treatment of nerve-related pain in patients with Guillain-Barré syndrome who received plasma exchange.
- Trial name
- NCT07907406
- Testing
- Gabapentin, Carbamazepine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Lahore General Hospital
Brain Tumor, Pediatric
Neurocognitive and Psychosocial Outcomes Among Pediatric Brain Tumor
This will be the first in-depth study to evaluate pretreatment and 12 months post-treatment, neurocognitive and psychological outcomes of children with brain tumor in Pakistan.
- Trial name
- PBT (NCT05709522)
- Testing
- Neurocognitive tools
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Aga Khan University
Infertility, Female, Infertility
Vitamin D and Polycystic Ovarian Syndrome (PCOS)
Primary Objectives: To evaluate the efficacy of metformin and Vitamin D supplementation on serum insulin and serum androgen levels (Total testosterone, Steroid Hormone Binding Globulin, Free Androgen Index) levels compared…
- Conditions
- Infertility, Female, Infertility, Vitamin D Deficiency
- Trial name
- NCT03989778
- Testing
- Vitamin D
- Where
- 2 sites in Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Aphasia
Learning to Communicate Successfully Approach for Urdu Speaking Patients With Chronic Aphasia
This study aims to develop and validate the Learning to Communicate Successfully Approach (LCSA), a culturally sensitive communication intervention manual for Urdu-speaking adults with chronic aphasia.
- Trial name
- LCSA (NCT07889778)
- Testing
- Learning to Communicate Successfully Approach (LCSA)
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Accidental Falls, Falls
SAFER Karachi - A Fall Prevention Intervention
The goal of this pilot study is to evaluate the feasibility, acceptability, and short-term effects of a culturally adapted and strengthened fall prevention program in older adults aged 60 years and above living in urban Karachi…
- Conditions
- Accidental Falls, Falls, Falls Injury, Mobility Difficulty
- Trial name
- SAFER (NCT07504237)
- Testing
- Stepping On Fall Prevention Program
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Bronchopulmonary Dysplasia (BPD)
Late Low-Dose Dexamethasone in Preterm Neonates Using DART Protocol
Premature babies, especially those who need breathing support for many days, are at risk of developing a long-term lung condition called bronchopulmonary dysplasia (BPD).
- Trial name
- NCT07904104
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 93 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Sacroiliac Joint Dysfunction
Effects of Pelvic Floor Exercises and Muscle Energy Techniques on Pain and Disability in Sacroiliac Joint Dysfunction
This clinical trial aims to evaluate whether combining pelvic floor exercises with muscle energy techniques provides greater improvement in pain and functional disability in adults with sacroiliac joint dysfunction compared to…
- Trial name
- NCT07275294
- Testing
- Muscle Energy Techniques with Hot pack and Transcutaneous Electrical Nerve Stimulation, Muscle Energy Techniques with Hot pack, Transcutaneous Electrical Nerve Stimulation and Pelvic floor Exercises
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Hemodynamics, Arterial Pressure
Comparison of Mean Arterial Pressure After Endotracheal Intubation in Patients Undergoing Spine Surgery With Pre-emptive Nitroglycerine Versus Dexmedetomidine
This randomized controlled study compared nitroglycerine and dexmedetomidine for controlling blood pressure after insertion of a breathing tube in adults undergoing spine surgery under general anesthesia.
- Trial name
- NCT07901023
- Testing
- Nitroglycerin (NTG), Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Mayo Hospital Lahore
Ulcerative Colitis (UC)
Oral Vitamin D3 Effect on Inflammatory Biomarkers in Ulcerative Colitis Patients
This randomized controlled trial aims to evaluate the effect of oral vitamin D3 supplementation on inflammatory biomarkers and disease activity in Pakistani patients with moderate ulcerative colitis.
- Trial name
- OVDIEIBUCP (NCT07269223)
- Testing
- Vitamin D3
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Cervicogenic Headache
Effects of Strain Counterstrain Versus Post Isometric Relaxation on Pain, Headache Frequency, and Quality of Life in Females With Cervicogenic Headache.
Cervicogenic headache is a secondary headache disorder associated with dysfunction of the cervical spine and surrounding muscles.
- Trial name
- SCS-PIR (NCT07897695)
- Testing
- Post Isometric Relaxation, Strain Counterstrain
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Qurat Ul Ain Ashfaq
Neonatal Respiratory Distress Syndrome
Heated, Humidified High-flow Nasal (HHHFN) Cannula vs Nasal Continuous Positive Airway Pressure in Respiratory Distress in Premature Neonates
Newborn babies who have difficulty breathing may need breathing support to help them receive enough oxygen. Two commonly used methods are heated, humidified high-flow nasal cannula (HHFNC), which delivers warmed, moist air and…
- Trial name
- NCT07891494
- Testing
- Heated Humidified High-Flow Nasal Cannula therapy, nCPAP
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Hypertension, Primary Hypertension
Text Message Support to Help Adults With Newly Diagnosed High Blood Pressure Control Their Blood Pressure in Primary Care Clinics in Germany and Pakistan
The goal of this clinical trial is to learn if text messages can help adults with newly diagnosed high blood pressure (hypertension) bring their blood pressure under control.
- Trial name
- NCT07878728
- Testing
- mHealth Text Message Program, Usual Care
- Where
- Pakistan
- Volunteers
- 1,295 people
- Sponsor
- GIFT University
Ventral Hernia Repair, Hernia Abdominal Wall
Onlay vs. Sublay Mesh Hernioplasty for Primary Ventral Hernia
This randomized controlled trial will compare the surgical outcomes of onlay mesh hernioplasty versus sublay mesh hernioplasty in patients with primary ventral wall hernias.
- Trial name
- NCT07896278
- Testing
- Onlay Mesh Hernioplasty, Sublay Mesh Hernioplasty
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Provincial Headquarter Teaching Hospital Gilgit
Hearing Disorder
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan
Objective: One objective of this study is to genetically map and identify mutated genes for human hereditary hearing loss. A second objective is to study the function of these genes in the auditory system using mouse models.
- Trial name
- NCT00341874
- Where
- Pakistan
- Volunteers
- 18,009 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Recurrent Bacterial Vaginosis
Probiotics as an Adjunct to Antibiotics for Recurrent Bacterial Vaginosis
This randomized clinical trial aims to compare the recurrence of bacterial vaginosis (BV) in women receiving probiotics alongside antibiotic treatment versus women receiving antibiotic treatment alone.
- Trial name
- NCT07893782
- Testing
- Probiotic Combination Cap/Tab
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Nishtar Medical University
Exercise Activity
Effect of a 12-Week Aerobic Exercise Program on Cardiac, Respiratory, Metabolic Health and Functional Fitness in Healthy Young Adults
This randomized controlled trial evaluated the effects of a structured 12-week multicomponent exercise program with an aerobic emphasis on cardiovascular, respiratory, metabolic, and functional fitness outcomes in healthy…
- Trial name
- NCT07892781
- Testing
- Structured Multicomponent exercise intervention program
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
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