Clinical trials: open to volunteers, in Pakistan
Episiotomy , Perineal Pain
Pudendal Nerve Block for Pain Relief During Episiotomy Repair: A Randomized Controlled Trial
Episiotomy is a surgical cut made in the perineum, the area between the vagina and anus, during vaginal childbirth. Repairing an episiotomy can cause pain, and adequate pain relief is important for maternal comfort during and…
- Trial name
- NCT07883473
- Testing
- Pudendal Nerve Block, Conventional Local Perineal Infiltration
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Palmoplantar Warts
Liquid Nitrogen Cryotherapy Versus CO₂ Laser for Palmoplantar Warts
This randomized clinical trial will compare the effectiveness of liquid nitrogen cryotherapy and carbon dioxide (CO₂) laser therapy for treating palmoplantar warts, which are human papillomavirus-related skin growths occurring on…
- Trial name
- NCT07881198
- Testing
- Liquid Nitrogen Cryotherapy, Carbon Dioxide (CO₂) Laser Therapy
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Acne Vulgaris
Clascoterone Versus Clindamycin Added to Adapalene/Benzoyl Peroxide for Moderate Facial Acne
This randomised trial compares two treatments added to the same standard acne gel in people with moderate facial acne. All participants will use adapalene 0.1%/benzoyl peroxide 2.5% gel at night.
- Trial name
- CLASCO-ACNE (NCT07881315)
- Testing
- Clascoterone 1% cream, Clindamycin 1% lotion, Adapalene 0.1%/benzoyl peroxide 2.5% gel
- Where
- Pakistan
- Volunteers
- 118 people
- Sponsor
- Allied Hospital Faisalabad
Melasma
Baseline Dermoscopic Vascular Score and Response to Oral Tranexamic Acid in Facial Melasma
Melasma is a common, long-lasting pigmentation disorder of the face. Some patients improve well with treatment and others improve little, and there is no simple way to predict this at the first visit.
- Trial name
- NCT07881328
- Testing
- Tranexamic acid, Standardised sunscreen and emollient
- Where
- Pakistan
- Volunteers
- 128 people
- Sponsor
- Allied Hospital Faisalabad
Odontogenic Infection, Maxillofacial Infection
Moxifloxacin Versus Clindamycin in the Management of Odontogenic Maxillofacial Infectious Processes
Investigators are conducting a trial to compare moxifloxacin against clindamycin for dental infections that spread to the face and jaw.
- Conditions
- Odontogenic Infection, Maxillofacial Infection, Cellulitis, Cellulitis of Face
- Trial name
- NCT07810244
- Testing
- Clindamycin, Moxifloxacin (400 mg)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Unilateral S1 Nerve Root Pain
Comparison of Efficacy of Caudal Versus Transforaminal Epidural Steroid Injections in Unilateral S1 Nerve Root Pain: A Randomized Controlled Trial
This study compares caudal and transforaminal epidural steroid injections for treating unilateral S1 nerve root pain. It evaluates pain relief, functional improvement, treatment satisfaction, quality of life, and complications…
- Trial name
- NCT07833553
- Testing
- Caudal Epidural Steroid Injection (CEI), Transforaminal Epidural Steroid Injection (TFI)
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- University of Health Sciences Lahore
Forward Head Posture
Comparative Effects of Pressure and Visual Biofeedback Training on Pain, Disability, Range of Motion Among Patients With Forward Head Posture Correction: A Randomized Controlled Trial
The study will take place at Akbar Niazi Teaching Hospital and AL kauther International hospital, Bhara Kahu, Islamabad with formal permission obtained from the institution.
- Trial name
- NCT07856433
- Testing
- VISUAL FEEDBACK, Pressure Biofeedback
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ibadat International University, Islamabad
Wilson's Disease
Trientine Tetrahydrochloride Administered Once a Day for the First Line Treatment of Wilson's Disease Patients.
The goal of this clinical trial is to learn if a new trientine tetrahydrochloride (TETA 4HCl) formulation administered once a day compared to d-Penicillamine (DPA) as a first line treatment for people living with Wilson's disease…
- Trial name
- TRADITiONAL (NCT07465718)
- Testing
- TETA 4HCl formulation, D-Penicillamine
- Where
- 10 sites in United States, China and 2 more
- Volunteers
- 38 people
- Sponsor
- Orphalan
Pulmonary Disease, Chronic Obstructive (COPD)
Comparative Effects of Coherent Breathing and Regular Paced Breathing on Dyspnea and Pulmonary Function in Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory condition of airways characterized by recurrent episodes of coughing, respiratory muscle weakness, lung hyperinflation and air trapping which ultimately leads to…
- Trial name
- NCT07875036
- Testing
- Coherent Breathing Group A, Regular Paced Breathing Group B
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Foundation University Islamabad
Peak Expiratory Flow Rate, Coronary Artery Bypass Graft Surgery
Additional Effects of Flutter With Conventional Chest Physiotherapy on Peak Expiratory Flow Rate and Chest Expansion in Post CABG Patients With COPD
Flutter therapy is an oscillating positive expiratory pressure (OPEP) technique that combines positive expiratory pressure with airway oscillations to facilitate mobilization and clearance of respiratory secretions.
- Conditions
- Peak Expiratory Flow Rate, Coronary Artery Bypass Graft Surgery, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT07875049
- Testing
- Conventional Chest Physiotherapy, Flutter device with conventional chest physiotherapy
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Foundation University Islamabad
Polycystic Ovarian Syndrome (PCOS), Quality of Life
High Intensity Interval Training Versus Mat Pilates in Women With PCOS
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age and is associated with obesity, insulin resistance, poor physical fitness, and reduced quality of life.
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Quality of Life, Physical Fitness
- Trial name
- NCT07875400
- Testing
- High-Intensity Interval Training (HIIT), Mat Pilates group, General mobility exercises
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Postmenopausal Osteoporosis
Effects of Sensorimotor Balance Training vs Digitally Augmented Core Stabilization in Women With Osteoporosis
This randomized controlled trial aims to compare the effects of sensorimotor-based balance training and digitally augmented core stabilization on postural control and fall risk in postmenopausal women with osteoporosis.
- Trial name
- NCT07875894
- Testing
- Sensorimotor-Based Balance Training, Digitally Augmented Core Stabilization
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Dental Anxiety in Children, Child Behaviour
Comparative Evaluation of Intranasal Atomized Midazalom Combined With Nitrous Oxide Versus Nitrous Oxide Monotherapy
The rationale of this trial is to evaluate whether combining intranasal atomized midazolam with nitrous oxide offers better behavior management leading to successful treatment completion in comparison with using nitrous oxide…
- Trial name
- NCT07876024
- Testing
- Midazolam (Intranasal), Nitrous oxide/oxygen inhalation sedation alone
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Gaucher Disease, Cerebroside Lipidosis Syndrome
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status.
- Conditions
- Gaucher Disease, Cerebroside Lipidosis Syndrome, Glucocerebrosidase Deficiency Disease, Glucosylceramide Beta-Glucosidase Deficiency Disease
- Trial name
- NCT00358943
- Where
- 317 sites in United States, Argentina and 50 more
- Volunteers
- 12,000 people
- Sponsor
- Genzyme, a Sanofi Company
Alveolar Osteitis
Comparative Efficacy of Amoxicillin, Metronidazole, and Chlorhexidine in Preventing Alveolar Osteitis
This study will compare the effectiveness of amoxicillin, metronidazole, and chlorhexidine in preventing alveolar osteitis (dry socket) following lower third molar extraction.
- Trial name
- NCT07833176
- Testing
- Amoxicillin, Metronidazole, Chlorhexidine
- Where
- Pakistan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Varicose Veins of Lower Limb
Subfascial Endoscopic Perforator Surgery (SEPS) Versus Open Ligation for Lower Limb Varicose Veins
The goal of this study is to compare two surgical treatments for lower limb varicose veins: subfascial endoscopic perforator surgery (SEPS) and open perforator ligation.
- Trial name
- SEPS (NCT07872150)
- Testing
- Subfascial Endoscopic Perforator Surgery(SEPS), Open Perforator Ligation(Stab Avulsion)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- King Edward Medical University
Supraspinatus Tendinitis
Anatomical Evaluation of Supraspinatus Through Ultrasonography and Biomechanical Measurements Following Blood Flow Restriction Therapy and Eccentric Exercise in Patients of Supraspinatus Tendinitis.
Patients of both gender groups with unilateral shoulder pain will be selected with age range 40-60 years from Sehat medical complex and randomly allocated into four groups (Group A, B, C and D) in Trial.
- Trial name
- NCT07873528
- Testing
- Blood flow restriction therapy, Eccentric Training, BFRT +ET
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sehat Medical Complex
Chronic Lung Diseases
Prospective Study on Antimicrobial RESIstance in Chronic Pulmonary DiseasE
This observational, multicentric prospective study aims to understand the prevalence and burden of antimicrobial resistance (AMR) in people with chronic lung diseases (CLD) across the globe, understanding also geographical…
- Trial name
- PRESIDE (NCT07874139)
- Where
- 68 sites in United States, Albania and 31 more
- Volunteers
- 683 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Acute Watery Diarrhea
Bacillus Clausii Versus Multistrain Probiotics for Acute Watery Diarrhea in Children
This randomized controlled trial will compare Bacillus clausii (Enterogermina) and a multistrain probiotic preparation (Ecotec) in children aged 1-5 years with acute watery diarrhea.
- Trial name
- NCT07660367
- Testing
- Enterogermina, Ecotec
- Where
- Pakistan
- Volunteers
- 138 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Forward Head Posture
Effects of a Wearable Device ,Phone App and Exercise on Cervico-thoracic Posture in University Students.
Forward head posture and thoracic kyphosis are among the most common postural problems in university students, driven largely by long hours of screen use and poor sitting habits.
- Trial name
- NCT07763327
- Testing
- Wearable postural biofeedback device, App based Postural Reminder, Conventional Cervicothoracic Exercise Therapy
- Where
- Pakistan
- Volunteers
- 87 people
- Sponsor
- Riphah International University