Clinical trials: Best Practice
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Evaluation of a Couple-Based Physical Activity Intervention
This clinical trial tests how well a couple-based physical activity (PA) intervention, Mates in Motion, works in patients undergoing hematopoietic cell transplantation (HCT) or chimeric antigen receptor T-cell therapy (CART) and…
- Trial name
- NCT06073951
- Testing
- Best Practice, Exercise Counseling, Exercise Intervention
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Immigrants
A Positive Activity Intervention to Promote Wellbeing in Romanian Immigrants
This study aims to test the efficacy of an intervention focused on promoting positive emotions (Best Possible Self - BPS) to improve the psychological wellbeing of Romanian immigrants living in Spain.
- Trial name
- NCT02493439
- Testing
- Best Possible Self, Daily Activities
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Cigarette Smoking
Health-Kit Enabled Mobile App for Tobacco Cessation
Tobacco use is the leading preventable cause of death in the US, contributing to more than 480,000 premature deaths each year. The Tobacco Treatment Guidelines underscore the need to offer patients who use tobacco products brief…
- Trial name
- NCT06292130
- Testing
- refresh
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Pro-Change Behavior Systems
Aquired Brain Injury, Traumatic Brain Injuries
Effectiveness of a Customized Digital Platform to Increase Coordination of Care and Uptake of Evidence-based Practices
Background: Cardiovascular and neurological conditions are major causes of disability worldwide. Early, intensive rehabilitation is essential but often challenging to access in current healthcare systems.
- Conditions
- Aquired Brain Injury, Traumatic Brain Injuries, Stroke, Cardiovascular Diseases
- Trial name
- NCT06867081
- Testing
- The intervention will be the BRILLIANT Platform, an online platform which provides five Modules aimed at increasing coordination of care and direct rehabilitation time
- Where
- 2 sites in Canada
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Rectal Cancer, Sigmoid Cancer
A Study of Perfusion of Colorectal Anastomosis Using FLuorescence AnGiography (FLAG-trial)
This is a randomized, controlled, parallel study to determine the difference in post-operative anastomotic leak rate of colorectal anastomosis where colon and rectal tissue perfusion is evaluated using fluorescence angiography…
- Trial name
- FLAG (NCT03390517)
- Testing
- Fluorescence angiography with indocianyne green
- Where
- Russia
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Suicide
Suicide Ideation Intervention in Nigeria
The research will use the Social Ecologic Model of behavior and WHO mhGAP framework to design a comprehensive intervention across three levels (individual, interpersonal, and social) of influence.
- Trial name
- NCT05103540
- Testing
- Comprehensive SEM-Based Program
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Babcock University
Vaccine Adverse Reaction, Vaccination; Complications
Improving the School Vaccination Experience: What CARDs Are You Going to Play?
Vaccination hesitancy is identified as a threat to global health by the World Health Organization (WHO). For adolescents undergoing vaccination at school, prior studies demonstrate that concerns about pain and/or fear of needles…
- Conditions
- Vaccine Adverse Reaction, Vaccination; Complications, Fear
- Trial name
- NCT03966300
- Testing
- Multi-faceted knowledge translation intervention
- Where
- Canada
- Volunteers
- 1,919 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Education, Medical, Colonoscopy
Coaching Language to Improve Endoscopy Training Quality
The goal of this randomized control study is to determine if the use of standardized coaching language by faculty trainers for teaching colonoscopy is associated with improved colonoscopy performance.
- Trial name
- CLIEnT (NCT05674500)
- Testing
- Educational Training on standardized coaching language, Educational Training on goal setting
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Physical Inactivity, Motor Activity
A Good Start Matters Intervention Study
The BC government and partners developed Active Play Standards and a capacity-building strategy to help childcare centers implement the Standards.
- Trial name
- NCT05669378
- Testing
- Appetite to Play +
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pectus Excavatum, Pain, Postoperative
Identification of Best Postoperative Analgesia Method Following a Minimally Invasive Repair of Pectus Excavatum
Pectus excavatum is the most common chest wall deformity in children, accounting for 90% of all congenital chest wall deformities. It occurs in one to eight per 1000 live births.
- Trial name
- (MIRPE) (NCT04211935)
- Testing
- Use of PCA, Use of ESB for postoperative pain control after MIRPE, Use of INC for postoperative pain control after MIRPE
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cancer, Anxiety
An Adaptive Dyadic Self-directed Coping and Self-management Skills Training Intervention for Caregivers of Individuals With Cancer
High-quality cancer care in Canada relies on family caregivers. Since cancer treatment is provided more and more in outpatient clinics, family caregivers now provide most of the support and care patients need when they return…
- Trial name
- NCT04255030
- Testing
- Coping Together Booklets and Workbook, Lay telephone coaching, Motivational Interviewing
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- St. Mary's Research Center, Canada
Mechanical Ventilation Complication, Postoperative Pulmonary Atelectasis
Flow Controlled Ventilation in Robot-assisted Laparoscopic Surgery
The optimization of ventilation is especially important during general anaesthesia, when active, physiologic respiration suspends and is replaced by non-physiologic mechanical positive pressure ventilation.
- Trial name
- FCV-IMPALA (NCT06256900)
- Testing
- Flow-controlled ventilation, Pressure-controlled ventilation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen
Not Flourishing Population
Efficacy of a Positive Psychology Intervention Through a Mobile App
The aim of this study is to analyze the efficacy of several variations of an already validated Positive Psychology Intervention (PPI) called Best Possible Self in not flourishing population.
- Trial name
- NCT03072680
- Testing
- BPS PAST, BPS FUT, DAILY ACTIVITIES
- Where
- 2 sites in Netherlands, Spain
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Behavioral Health Challenges
Brief Intervention at Adult Education
Many Americans fail to receive their high school diploma. Individuals enrolled in Adult Education classes have exited the K-12 education system without a high school diploma.
- Trial name
- NCT07102914
- Testing
- Screening, Brief Intervention and Referral for Treatment (SBIRT)
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Yale University
Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm
Parenting Support Intervention for Families Coping With Metastatic or Locally Recurrent Solid Tumor Diagnosis
This clinical trial examines the acceptability and effect of a parenting support intervention for families coping with solid tumor that has spread to other places in the body (metastatic) or has come back (recurrent).
- Trial name
- NCT05059678
- Testing
- Best Practice, Educational Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
PTSD, Depression
Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care
The most common reasons Veterans seek VA addiction and mental health care is for help with opioid and alcohol misuse, depression and PTSD.
- Conditions
- PTSD, Depression, Alcohol Use Disorder, Opioid Use Disorder
- Trial name
- NCT04356274
- Testing
- Participatory System Dynamics (PSD), Audit and Feedback (AF)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Aortic Stenosis
Construction and Application Plan of Home Cardiac Rehabilitation for Patients Undergoing TAVR
Cardiac rehabilitation is a long-term process, but patients have poor compliance with cardiac rehabilitation. The theory of behavior change rotation aims to comprehensively intervene from three aspects: ability, opportunity, and…
- Trial name
- NCT06418555
- Testing
- A home rehabilitation program centered on exercise
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Heart Failure
Handheld Ultrasound at Remote Locations
Heart failure causes a large patient and financial burden on the health care system. Pocket ultrasound imaging devices are utilized to improve time to correct diagnosis.
- Trial name
- NCT03547076
- Testing
- Focused ultrasound diagnostics
- Where
- Norway
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Helse Nord-Trøndelag HF
Colorectal Neoplasms
Screening of Colorectal Cancer in the Public Healthcare Sector in Argentina
Introduction: Early detection of certain types of cancer significantly increases the likelihood of successful treatment and reduces mortality from these causes.
- Trial name
- NCT04293315
- Testing
- Improvement Cycles
- Where
- Argentina
- Volunteers
- 1,520 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical Effectiveness and Health Policy
Chemotherapy-Induced Peripheral Neuropathy, Malignant Solid Neoplasm
Evaluating a Mobile Health Application Intervention for Caregiver Instruction in Manual Therapy for Chemotherapy-Induced Peripheral Neuropathy
This clinical trial assesses the impact of a family caregiver-delivered massage technique for use in cancer survivors with chemotherapy-induced peripheral neuropathy (CIPN).
- Conditions
- Chemotherapy-Induced Peripheral Neuropathy, Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm
- Trial name
- NCT06945380
- Testing
- Best Practice, Comparator Program, Best Practice, Usual Care, Internet-Based Intervention
- Where
- United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic