Clinical trials: sponsored by Research Inc
Acne, Atopic Dermatitis
Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers
The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases.
- Conditions
- Acne, Atopic Dermatitis, Chronic Hand Eczema, Hidradenitis Suppurativa
- Trial name
- NCT05994976
- Testing
- Blood samples collection, Oral samples collection, Hair samples collection
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Infectious Diseases, Antimicrobial Drug Resistance
A Phase 1 Study of the Safety and Tolerability of Single and Multiple Ascending Doses of BWC0977 in Healthy Volunteers
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of single and multiple intravenous doses of BWC0977 when administered to healthy adult volunteers.
- Trial name
- NCT07029932
- Testing
- BWC0977
- Where
- Australia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bugworks Research Inc.
Delayed Onset Muscle Soreness (DOMS), Exercise-Induced Muscle Soreness
A Study of Mitragynine Formulations for Exercise-Induced Muscle Soreness in Healthy Adults
This Phase II randomized, double-blind, placebo-controlled study will evaluate the safety, tolerability, and physical dependence potential of mitragynine-containing formulations after 28 days of use and assess their effects on…
- Trial name
- NCT07809282
- Testing
- SpecioTea, MitraPlex
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Traditional Naturals Research Inc.
Mental Health Issue, Mental Health Disorder
Pilot Study on the Clinical Utility of the Tulsa Life Chart
The proposed study aims to examine the usability, utility, and feasibility of the Tulsa Life Chart (TLC) in a sample of patients seeking mental health treatment and their healthcare providers.
- Conditions
- Mental Health Issue, Mental Health Disorder, Assessment, Self
- Trial name
- NCT05523843
- Testing
- Tulsa Life Chart (TLC)
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Sarcopenia, Body Composition
Validation of a Body-Composition Segmentation Software on a Diverse Public CT Scan Cohort
This study evaluates the standalone performance of Soma, a deep-learning software developed by Nucleo Research, Inc. for the automated segmentation of body-composition tissues (skeletal muscle, subcutaneous adipose tissue…
- Conditions
- Sarcopenia, Body Composition, Obesity
- Trial name
- SOMA (NCT07600866)
- Testing
- Soma Body-Composition Segmentation Software
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nucleo Research, Inc.
Major Depressive Disorder
Neural Response to Inflammatory Challenge in Major Depressive Disorder
This is a parallel group, double-blinded, placebo-controlled study. Participants with MDD (n=90) and HC (n=90) will be randomly assigned (2:1) to receive either lipopolysaccharide (LPS) (0.8ng/kg of body weight) or placebo (same…
- Trial name
- NCT04751331
- Testing
- LPS, Saline
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Bipolar Disorder I or II, Healthy (Controls)
Decoding Emotional Dynamics in Bipolar Disorder
The goal of this neuroimaging study is to investigate how emotional states fluctuate in people with bipolar disorder (BD) compared to healthy controls, and to understand the neural mechanisms driving mood instability.
- Trial name
- NCT07221864
- Testing
- Think and Regulate Affective State Task
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Child Abuse Sexual
Evaluation of Circles of Safety
Using a matched cluster randomized control design, the proposed study will evaluate a child sexual abuse (CSA) primary prevention strategy, Circles of Safety®.
- Trial name
- NCT07526142
- Testing
- Circles of Safety
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Center for Violence Prevention Research Inc
Healthy
BPIT 5-Line Pilot: Interventional Study on Strength, HRV & Injury Risk Reduction (n=23)
This prospective, single-center, interventional pilot (n=23) evaluates the 5-Line Principle of Balanced Intensity Training (BPIT) over 6 weeks at GFFI Fitness Academy.
- Trial name
- BPIT 5-Line (NCT07296640)
- Testing
- BPIT 5-Line Training
- Where
- India
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Physical Fitness
BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation
This prospective, multi-site, single-arm interventional study evaluates the 5-Line Principle of Balanced Progressive Intensity Training (BPIT) over 5 weeks in healthy adults aged 18-65 years.
- Trial name
- BPIT_5LINE_369 (NCT07256717)
- Testing
- Balanced Progressive Intensity Training (BPIT) 5-Line Method
- Where
- 10 sites in United States, India
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Depression, Functional Impairment
The Health and Social Consequences of Depression Among the Elderly
Mental illnesses often go undiagnosed or untreated in low-income settings. Mental health care may be especially important for the elderly - events in the lives of the elderly, like illnesses or deaths of peers, may put these…
- Trial name
- NCT05856552
- Testing
- CBT, Group Activities
- Where
- 2 sites in India
- Volunteers
- 5,370 people, healthy volunteers welcome
- Sponsor
- National Bureau of Economic Research, Inc.
Healthy Controls
Dose-Dependent Effects of Low-Intensity Focused Ultrasound
Low-intensity focused ultrasound (LIFU) has emerged as a tool to modulate the activity of deep brain structures noninvasively and reversibly, with anatomical precision.
- Trial name
- NCT07099950
- Testing
- Low-intensity focused ultrasound
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Loneliness
The Economic Consequences of Loneliness Among the Elderly
Elderly individuals across the world are increasingly living alone. However, little is known about the effects of loneliness on economic and health outcomes.
- Trial name
- NCT04225845
- Testing
- Phone therapy, Cash transfer
- Where
- India
- Volunteers
- 1,120 people, healthy volunteers welcome
- Sponsor
- National Bureau of Economic Research, Inc.
Safety Issues, Tolerance
Phase1 First in Human Ascending Dose Study to Evaluate the Safety and Tolerability of FC-12738 in Health Adults
A Phase I, Randomized, Double-Blind, Placebo-Controlled, First-in-human, Single-Ascending-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of retro enversio (RT) thymopentin in Healthy Adult…
- Trial name
- NCT05978908
- Testing
- FC-12738, Saline
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Neurodegenerative Disease Research Inc
Safety Issues, Tolerability
Single Ascending Dose and Multiple Ascending Dose Study of AVR-48
This is a Phase 1 (healthy adult volunteers), 2-part, double-blind, randomized, placebo controlled trial to evaluate the safety and pharmacokinetic (PK) profiles of escalating single doses of AVR-48 versus placebo (SAD) and…
- Conditions
- Safety Issues, Tolerability, Pharmacokinetics, Pharmacodynamics
- Trial name
- NCT06847698
- Testing
- AVR-48
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AyuVis Research, Inc.
Soft Drink Consumption, Sugar-sweetened Beverages
Are Sugar-Sweetened Beverage Information Labels Well-Targeted
We will study the extent to which soft drink information labels -- designed to curb unhealthy consumption -- are well-targeted to the most biased consumers.The study team will deploy novel methods for evaluating the targeting…
- Conditions
- Soft Drink Consumption, Sugar-sweetened Beverages, Information Labels
- Trial name
- NCT05038163
- Testing
- Nutrition Facts, Text Warning, Graphic Warning
- Where
- United States
- Volunteers
- 5,845 people, healthy volunteers welcome
- Sponsor
- National Bureau of Economic Research, Inc.
Head Start Recruitment, Selection, and Enrollment Practices
Head Start REACH: Strengthening Outreach, Recruitment, and Engagement Approaches with Families.
Mathematica, funded by the Administration for Children and Families (ACF) Office of Planning, Research, and Evaluation (OPRE) in the U.S.
- Trial name
- HeadStartREACH (NCT06670664)
- Testing
- No intervention
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Gout
Assessing the Role of the NLRP3 Inflammasome in Intercritical Gout
Gout is an autoinflammatory disease characterized by flares of painful joint inflammation. This inflammation occurs in response to uric acid that crystallizes.
- Trial name
- NCT04125459
- Testing
- Joint Biopsy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Attune Health Research, Inc.
Major Depressive Disorder
Low Intensity Ultrasound Neuromodulation of Repetitive Negative Thinking In Depression
The investigators propose to use low-intensity transcranial focused ultrasound (LIFU), a novel neuromodulation method, to probe the causal involvement of individually defined components of an anteromedial brain circuit in the…
- Trial name
- NCT05697172
- Testing
- Low-intensity focused ultrasound
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anorexia Nervosa
Gastrointestinal Interoception in Anorexia Nervosa
Anorexia nervosa (AN) has among the highest mortality rate of any psychiatric illness, yet we have a poor understanding of the biological causes of this disorder.
- Trial name
- NCT05111977
- Testing
- Vibrant capsule
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.