Clinical trials: sponsored by UNC Lineberger Comprehensive Cancer Center
Human Immunodeficiency Virus (HIV), Human Papillomavirus (HPV)
C-3002: Enhancing Cervical Cancer Screening Access and Follow-up Care at 'CASCADE' Clinical Sites in the United States
The purpose of the CASCADE-3002 project is to improve access to cervical cancer screening among women with Human Immunodeficiency Virus (HIV) receiving care at U.S.-based CASCADE clinical sites.
- Conditions
- Human Immunodeficiency Virus (HIV), Human Papillomavirus (HPV), Cervical Cancer, Cervical Precancer
- Trial name
- CASCADE3002 (NCT07520188)
- Testing
- Qualitative interviews, Focus groups
- Where
- 2 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Colorectal Cancer
The PharmFIT Study
This study will conduct a randomized controlled trial to assess the impact of a pharmacy-based FIT intervention, Pharmacy-based FIT (PharmFIT), on colorectal cancer screening (CRC) screening rates in primary care patients who are…
- Trial name
- PharmFIT (NCT06656936)
- Testing
- PharmFIT
- Where
- 2 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cancer, Diabetes
Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes
This study investigates the feasibility, acceptability, and preliminary efficacy of enCompass Humana, a social support intervention for caregivers of patients with cancer and diabetes.
- Trial name
- enCompass (NCT07061652)
- Testing
- Survey, the resource booklet from the American Cancer Society
- Where
- 3 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Health Behavior
Consumer Perceptions of Alcoholic Beverages
This study aims to examine the effects of marketing claims on alcoholic beverage packaging on alcohol consumers' perceptions and intentions.
- Trial name
- NCT07226271
- Testing
- Natural Claim, Sugar Claim, Fruit Claim
- Where
- United States
- Volunteers
- 1,534 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Vaping Behavior
Impact of E-Cigarette Prevention Messages on Adolescents
The purpose of this trial is to determine whether a vaping prevention text message program reduces susceptibility to vaping among adolescents and young adults.
- Trial name
- NCT05985538
- Testing
- Vaping prevention text messages, Wellness behaviors text messages
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Human Papilloma Virus
Impact of Financial Incentives
This trial will look at the impact of clinic-level financial incentives to improve provider communication and increase HPV vaccine uptake. Some clinics will receive communication training.
- Trial name
- NCT05744960
- Testing
- Communication training, financial Incentive
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Metastatic Breast Cancer, End of Life
Evaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Specific Prognostic Calculator Among Clinicians
I this qualitative study, Investigators will conduct semi-structured interviews with clinicians that are involved in the care of patients with breast cancer to evaluate the acceptability, appropriateness, and…
- Trial name
- NCT05440929
- Testing
- Clinician Qualitative Interview
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cognitive Burden, Cognitive Symptom
Evaluation of Impact of AI Assistance on Workload Associated w Preparation of Rare Tumor Case Repts
The goal of this study is to explore cognitive burden perceptions among physicians in relation to case report writing. Furthermore, this study evaluates the use of artificial intelligence (AI) assistance as a tool to reduce…
- Trial name
- NCT06026098
- Testing
- Artificial Intelligence
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Pancreas Cancer, Metastatic, Pancreas Carcinoma
The STRONG Nutrition Support Study for People With Pancreatic Cancer
This single-center pilot randomized controlled trial evaluates the feasibility, acceptability, and preliminary effects of STRONG, a digital nutrition support app delivered alongside remote dietitian-led nutrition counseling, in…
- Trial name
- STRONG (NCT07826780)
- Testing
- STRONG intervention App, individualized remote dietitian
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cancer
Incorporating Biometric Data for Patients Receiving Concurrent Chemotherapy & RT
This study will assess the feasibility of incorporating biometric data via wearable health technology (WHT) into the radiation oncology (RO) clinic workflow for patients receiving concurrent radiation therapy and systemic therapy…
- Trial name
- NCT05937659
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Obesity
Evaluation of Child Care Staff Weight Management Program
The goal of this 12-month cluster clinical trial is to evaluate if improving child care providers' health behaviors using an online provider weight management program elicits meaningful change in dietary and physical activity…
- Trial name
- NCT05656807
- Testing
- Go NAPSACC Enhanced, Go NAPSACC
- Where
- United States
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Pancreas Cancer
A Decision Support Tool for Pancreatic Cancer Screening -Aim 2
Pancreatic cancer has a rising incidence and poor survival. Early detection in high-risk individuals may substantially improve outcomes.
- Trial name
- NCT07808671
- Testing
- Electronic Decision Support Tool
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Down Syndrome, Child Obesity
HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome
The goal of this project is to evaluate an adapted health promotion program, HomeGrown, designed to improve the health of young children with Down syndrome by supporting families in making healthy home environmental changes.
- Trial name
- HomeGrown (NCT07296861)
- Testing
- The HomeGrown, Waitlist
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Vaping
Evaluating Narrative Vaping Prevention Video Ads for Adolescents and Young Adults
The purpose of this study is to evaluate the persuasive effectiveness of narrative advertisements: with acted-out plots (where characters enact a vaping-related experience) versus narrative advertisements without acted-out plots…
- Trial name
- NCT07767929
- Testing
- Acted-Out Narrative Ads, Non-Acted-Out Narrative Testimonial Ads, Neutral Control Videos
- Where
- 2 sites in United States
- Volunteers
- 1,910 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Breast Cancer, Lymph Node Metastasis
Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast Cancer
The purpose of this study is to determine how circulating tumor DNA (ctDNA), a sign of minimal residual disease (MRD), is detectable after surgery in patients with early HR+/HER2- breast cancer that has spread to 1-3 lymph nodes.
- Trial name
- NCT07025785
- Testing
- Circulating tumor DNA
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Overweight and Obesity, Overweight
Piloting a Reinforcement Learning Tool for Individually Tailoring Just-in-time Adaptive Interventions
The purpose of this pilot study is to conduct a 12-week pilot feasibility study testing usability of a reinforcement learning model (AdaptRL) in a weight loss intervention (ADAPT study).
- Conditions
- Overweight and Obesity, Overweight, Obesity
- Trial name
- NCT05751993
- Testing
- ADAPT
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cervix Cancer, Screen HPV-positive
Uniting Trusted Community Messengers to Improve Access to Cervical Cancer Screening in Rural North Carolina
The purpose of this study is to test the feasibility and acceptability of a multi-level, community-engaged intervention to increase access to cervical cancer screening using human papillomavirus (HPV) self-collection (HPVSC)…
- Trial name
- NCT07294066
- Testing
- Human papilloma virus screening
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Leukemia, Acute Leukemia
Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)
Acute lymphoblastic leukemia (ALL) is the most common cancer in children and, along with lymphoblastic lymphoma, represents the most common group of childhood lymphoid malignancies.
- Conditions
- Leukemia, Acute Leukemia, Acute Lymphoid Leukemia, Lymphoblastic Lymphoma
- Trial name
- STEP-ALL (NCT07634653)
- Testing
- Exercises
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Tobacco Use
Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Eye Tracking
The goal of this research is to determine how removal of little cigar and cigarillo (LCC) flavor descriptors on packaging impacts attention and affective responses to LCC warnings.
- Trial name
- NCT06546618
- Testing
- LCC pack stimuli images
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Vaping
Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults
The purpose of the Aim 2 study is to assess the perceived effectiveness of vaping prevention ads among adolescents and young adults and identify which features of video ads predict perceived message effectiveness.
- Trial name
- NCT07116837
- Testing
- Vaping prevention video ads
- Where
- United States
- Volunteers
- 3,113 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center