Clinical trials: enrolling by invitation
Congenital Heart Disease (CHD)
Can Smartphones Listen to Your Heart? A Performance Study on Detecting Inborn Heart Diseases in Your Heart Sounds
This observational study aims to assess the performance of the software called ausculto™. ausculto™ is a collection of computer algorithms that intend to analyse heart sounds recorded from the built-in microphone of a smartphone…
- Trial name
- AUSC-CHD (NCT07376785)
- Testing
- Computer algorithms
- Where
- 2 sites in Hong Kong
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Alzheimer's Disease, Dementia With Lewy Bodies
Imaging of Brain Amyloid Plaques in the Aging Population
This is a prospective, open label, non-therapeutic, diagnostic imaging study. The purpose of this study is to utilize Pittsburgh Compound B positron emission imaging (PiB PET) to ascertain the relationship between change in…
- Conditions
- Alzheimer's Disease, Dementia With Lewy Bodies, Frontotemporal Dementia, Vascular Dementia
- Trial name
- NCT00950430
- Testing
- Pittsburgh Compound B (C-11 PiB), F-18 FDG, Tau (18-F-AV-1451)
- Where
- United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dietary Behavior, Free Sugar
This Trial Aims to Assess the Effects of Three Different Taste-based Dietary Recommendations for Reducing Free Sugar Intakes on Free Sugar Consumption in UK High Free Sugar Consumers
This randomised controlled trial aims to assess the effects of three different taste-based dietary recommendations for reducing free sugar intakes on free sugar consumption in UK high free sugar consumers.
- Conditions
- Dietary Behavior, Free Sugar, Sweet Taste
- Trial name
- NCT06925932
- Testing
- Dietary advice - Sweet taste, Dietary advice - Taste, Dietary advice - No taste
- Where
- United Kingdom
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Orthodontic Anchorage Procedures
Failure Rate of Infra-Zygomatic Orthodontic Mini-Screws
The goal of this randomized clinical study is to assess the factors associated with the failure rate of infra-zygomatic crest orthodontic mini-screws used for anchorage reinforcement during orthodontic treatment.
- Trial name
- NCT07661277
- Testing
- Immediate loading infra-zygomatic mini-screw, Delayed loading infra-zygomatic mini-screw
- Where
- Bangladesh
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Healthy Volunteers
Induction of Dreaming With EEG and Anesthesia in Healthy Adults
This open-label, randomized crossover study in healthy adults tests two propofol protocols to produce distinct experiential states.
- Trial name
- IDEA (NCT07198711)
- Testing
- Propofol - Emergence-from-LOR Protocol, Propofol - Light Sedation Protocol
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy
FIT FIRST for the Bones
This study aims to conduct a cluster RCT intervention study with adolescents in Denmark and investigate whether the FIT FIRST concept can improve young people's bone health.
- Trial name
- FIT FIRSTftB (NCT07659587)
- Testing
- FIT FIRST
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Immediate Implant Placement in Maxillary Molar Region
Evaluation of the Accuracy of Root Guided Immediate Implant Placement at Maxillary- Molar Region
Twenty patients with non restorable maxillary molar that indicate to immediate implant will be included in this study. The patients will be divided randomly (10 patients each group).
- Trial name
- NCT07658144
- Testing
- root guide technique, surgical guide technique
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cancer Survivorship, Primary Care
KanSurvive 2.0: Testing Enhanced Models of Cancer Survivorship Care for Rural Cancer Survivors in Primary Care Practice
Rural cancer survivors experience a higher risk of negative health outcomes and require coordinated care to address the many effects of cancer and its treatment.
- Trial name
- NCT07528963
- Testing
- KanSurvive telementoring and education, Practice facilitation for quality improvement, Obesity management toolkit
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Hyperuricemia With or Without Gout
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Oral F-02-2-Na Tablets in Adult Subjects
The primary objective of this study is to evaluate the safety, tolerability and pharmacokinetic (PK) profiles of ascending single orally administered doses of F-02-2-Na in adult subjects (to include the Mass Balance) \& multiple…
- Trial name
- NCT07324434
- Testing
- F-02-2-Na Tablet (0.5 mg), F-02-2-Na Tablet (5 mg), F-02-2-Na Tablet (10 mg)
- Where
- China
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Guangdong Hengqin Novagains Biopharmaceutical Co., Ltd.
Adhesive Capsulitis
AI-Assisted Ultrasound Therapy for Adhesive Capsulitis
This study aims to integrate artificial intelligence with ultrasound imaging to investigate the dynamic biomechanical characteristics of adhesive capsulitis and to compare the therapeutic effectiveness of three ultrasound-guided…
- Trial name
- NCT07599059
- Testing
- Dual-Target Injection, Rotator Interval Injection, Posterior Recess Injection
- Where
- Taiwan
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Pain, Fear
The Effect of ShotBlocker and Finger Puppet on Pain and Fear During Blood Drawing in Children
Blood sampling can cause pain, anxiety, and fear in children. Such negative experiences may cause the child to develop negative attitudes toward treatment and care procedures.
- Conditions
- Pain, Fear, Blood Sampling, Children
- Trial name
- NCT07654192
- Testing
- Distraction techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Mammogram Uptake, Breast Cancer
Trial to Evaluate the Impact of Various Pragmatic Interventions to Increase Mammography Uptake Among Defaulted Repeat Screeners in Singapore
Breast cancer is the most common cancer among women in Singapore, accounting for nearly 30% of all female cancers. While regular biennial mammography can reduce mortality, screening rates in Singapore remain low at 34.7%; well…
- Conditions
- Mammogram Uptake, Breast Cancer, Breast Neoplasm, Early Detection of Cancer
- Trial name
- REMIND1 (NCT07651345)
- Testing
- Arm 2: One mailed reminder, Arm 3: Two mailed reminders, Arm 4: Mailed reminder with prescheduled appointment
- Where
- Singapore
- Volunteers
- 12,750 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Spinal Cord Injury, Traumatic Brain Injury
The National Center for Testing Treatments in Chronic Spinal Cord and Traumatic Brain Injury
The NCTT is a prospective, multicenter, observational research network for subjects with chronic spinal cord and/or chronic traumatic brain injury.
- Trial name
- NCTT (NCT02769416)
- Testing
- Data and sample repository
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Muscle Stretching Exercise, Range of Motion, Articular
Comparison of Eccentric Exercise and Static Stretching on Muscle Flexibility
Background: Muscle flexibility is a fundamental physical quality for body development, daily life and sports activities, and also for maintaining muscle quality during aging.
- Trial name
- COEESS (NCT06469346)
- Testing
- Nordic Hamstring Eccentric Exercise Training, Passive Hamstring Static Stretching Training, Control Group
- Where
- Chile
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Breast Cancer
MammoVerse: Clinicians Focus Group
The purpose of this study is to gather insights from clinicians who provide care to women diagnosed with breast cancer in Florida in order to identify gaps in emotional and mental health support encountered throughout the cancer…
- Trial name
- NCT07644845
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Ventral Incisional Hernia
Shear-Wave Elastography
Prospective cohort study of patients with midline ventral incisional hernia with a range of hernia morphology who plan to undergo open retromuscular VHR.
- Trial name
- ELASTOGRAPHY (NCT06306976)
- Testing
- Elective Midline Laparotomy, Imaging: Ultrasound, Tensiometry
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Patient-Ventilator Interaction, Asynchrony, Patient-Ventilator
Standardising Terminology, Classification, Diagnostic Recognition and Reporting of Patient-ventilator Interactions: Protocol for an International Delphi Consensus Study
Patient-ventilator interaction describes how a mechanically ventilated patient's breathing effort aligns with ventilator support.
- Trial name
- INTERACT (NCT07638540)
- Testing
- Modified Delphi consensus survey
- Where
- Kuwait
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al Adan Hospital Kuwait
Cardiovascular Risk Factors, Serious Mental Illness
Reducing Disparities in Cardiovascular Health in Community Mental Health Settings: Optimizing Implementation Strategies
In this trial, the investigators will examine the uptake of the evidenced-based IDEAL Goals program, a heart disease risk reduction program, while testing different implementation strategies with our partners in Michigan and…
- Trial name
- NCT06674616
- Testing
- Replicating Effective Programs, Coaching, Facilitation
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Comparative Effectiveness Research, Regional Block
Serratus Posterior Superior Intercostal Plane Block Versus Erector Spinae Plane Block in Thoracic Spine Surgeries
Spinal surgeries coincide with high level of pain due to extensive dissection and muscle retraction so inadequate pain control delays patient recovery, rehabilitation and also is an important source of patient dissatisfaction…
- Trial name
- NCT07646184
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Erector spinae block
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cognitive Impairment
Neuroimaging Study
The researchers are trying to gather information and learn more about imaging tests in racially different people who are cognitively normal or have dementia.
- Trial name
- NCT03618186
- Testing
- Tau PET scan
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
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