Clinical trials: Experimental Group
Advanced Pancreatic Cancer
A Trial Comparing Gemcitabine With and Without IMM-101 in Advanced Pancreatic Cancer
To compare, in patients with advanced pancreatic cancer, the effects of IMM-101 in combination with gemcitabine to gemcitabine alone on safety and tolerability (including QoL), clinical signs and symptoms of disease, selected…
- Trial name
- NCT01303172
- Testing
- IMM-101, Gemcitabine
- Where
- 21 sites in Cyprus, Ireland and 3 more
- Volunteers
- 110 people
- Sponsor
- Immodulon Therapeutics Ltd
Polycystic Ovary Syndrome, Infertility
Effect of Progestin-Induced Withdrawal Bleed on Ovulation Induction Cycles With Clomiphene Citrate
Women with polycystic ovary syndrome (PCOS) can suffer from infertility because they do not produce an egg each month, resulting in irregular periods.
- Trial name
- NCT01966575
- Testing
- Progestin
- Where
- Canada
- Sponsor
- University of British Columbia
Stress, Burnout Syndrome
Efficacy of a Mindfulness Program to Reduce Stress and Burnout in Professionals of Medicine and Nursing (MINDUUDD)
The objective is to check whether a training program in mindfulness and self-pity based on a 4-session intervention (abbreviated program) is as effective as the standard 8-session MBSR program in reducing work stress and burnout…
- Trial name
- MINDUUDD (NCT03629457)
- Testing
- Mindfulness and Mindful Self-Compassion
- Where
- Spain
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Luis A Perula
Nursing Caries, Pain
The Effect of Hand Puppets and Kaleidoscope on Pain and Fear in Preschool Children
This study aimed to determine the effects of hand puppets and kaleidoscopes on some emotional parameters in preschool children who underwent skin prick testing at the pediatric allergy and immunology outpatient clinic.The study…
- Conditions
- Nursing Caries, Pain, Fear of Pain
- Trial name
- NCT06512857
- Testing
- Hand puppet method, Kaleidoscope method
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Firat University
Shoulder Tendinopathy
Immersive Virtual Reality Versus Conventional Physiotherapy for Shoulder Tendinopathy
Immersive virtual reality (VR) has emerged as a promising tool to support therapeutic exercise by increasing patient motivation, promoting movement through gamification, and potentially reducing pain perception during movement.
- Trial name
- HOMVR (NCT07592156)
- Testing
- Conventional Therapeutic Exercise, Immersive Virtual Reality-Based Therapeutic Exercise
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Burgos
Atrophic Vaginitis
Phase I-B Study to Evaluate the Safety, Tolerability and Efficacy of IZN-6NVS for the Treatment of AV and DIV
In this open label study, 50 eligible women will be assigned to receive the investigational product (IZN-6NVS) - 2.5 g of cream/day for 14 days, followed by 3 applications per week for the next 4 weeks.
- Trial name
- NCT02313545
- Testing
- IZN-6NVS Cream
- Where
- 3 sites in United States, Israel
- Volunteers
- 50 people
- Sponsor
- Izun Pharma Ltd
Anesthesia
Difference of Information Gain Between Video-base and Doctor Interview After Preanesthetic Visit
To investigate the differenec of patients' satisfaction and information gain betweem face-to-face interview and video introduction
- Trial name
- NCT03344445
- Testing
- video-assisted pre anesthesia explain
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- IRB of NTUH Hsin-Chu Branch
Stress Urinary Incontinence, Incontinence, Urinary
Comparison Between a Telerehabilitation Program for Urinary Incontinence Versus a Conventional Face-to-face Program
Urinary incontinence (UI) is defined as any involuntary loss of urine. It affects a significant percentage of the population, mainly female, with a prevalence of 21.4% in Portuguese women, having a negative impact on quality of…
- Conditions
- Stress Urinary Incontinence, Incontinence, Urinary, Covid19, Pelvic Floor Muscle Weakness
- Trial name
- NCT05114395
- Testing
- Pelvic Floor Telerehabilitation Program, Pelvic Floor Face-to-Face Program
- Where
- 2 sites in Portugal
- Volunteers
- 39 people
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Aortic Dissection
Effects of Intraoperative Hemoperfusion on Acute Kidney Injury After Aortic Dissection
Acute kidney injury (AKI) is a common and serious complication after aortic dissection (AD), and it is closely related to the inflammatory response associated with cardiopulmonary bypass.
- Trial name
- EIHPOAKIAD (NCT05331495)
- Testing
- Intraoperative Hemoperfusion
- Where
- China
- Volunteers
- 206 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Renal Dialysis
Clinical Trial on a Novel Blood Pumping System in 4008A Hemodialysis Machine
The aim of this clinical trial will be to verify the feasibility of using an impeller system instead of a roller pump for hemodialysis, using the established 4008 hemodialysis system and a Convergence Dialyzer with design changes…
- Trial name
- NCT05217095
- Testing
- Convergence Dialyzer
- Where
- North Macedonia
- Volunteers
- 8 people
- Sponsor
- D.med Consulting GmbH
Pain, Postoperative, Obstructive Sleep Apnea-hypopnea Syndrome
Postoperative Pain Management on Uvulopalatopharyngoplasty Patients
This is a randomized controlled study, aimed to investigate the effects of dinalbuphine sebacate (DS) on patients having uvulopalatopharyngoplasty (UPPP). DS is a prodrug of nalbuphine, a mixed agonist-antagonist opioid.
- Conditions
- Pain, Postoperative, Obstructive Sleep Apnea-hypopnea Syndrome, Pain, Acute
- Trial name
- NCT05825495
- Testing
- Dinalbuphine sebacate, Routine practice
- Volunteers
- 78 people
- Sponsor
- Li-Jen Hsin
Anthrax, Anthrax Immunisation
Anthrax AV7909 Liquid vs Lyophilized
This is a randomized, parallel-group, double-blind, Phase 1 study designed to assess safety, tolerability and immunogenicity 2 formulations of adjuvanted anthrax vaccine (AV7909), lyophilized and liquid.
- Trial name
- NCT04660201
- Testing
- AV7909
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Periodontal Disease, Melatonin
Adjunctive Topical Melatonin Gel in Non-Surgical Periodontal Therapy for Periodontitis
The goal of this clinical trial is to evaluate the clinical effectiveness of adjunctive topical melatonin gel when used with non-surgical periodontal therapy (NSPT) in adult patients with periodontitis.
- Trial name
- NCT07605767
- Testing
- Topical 5% Melatonin Gel
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Liaquat College of Medicine and Dentistry
Patellofemoral Pain Syndrome
Tibiofemoral Mobilization in Patellofemoral Pain Syndrome
The aim of this research was to determine the effects of tibiofemoral joint mobilization in patients of patellofemoral pain syndrome. Tibiofemoral joint mobilization effects on pain and Range of Motion (ROM) in knee joint.
- Trial name
- NCT04225000
- Testing
- Exercise Group, Mobilization Group
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Alzheimer Disease
The Effect of Music in Alzheimer's Patients
This study was randomized controlled study conducted to determine the effect of Nihavent theme on reducing adjustment difficulties in Alzheimer's patients.
- Trial name
- NCT05125536
- Testing
- Music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Dental Caries
Two Years Survival Rate of Class II ART Restorations in Primary Molars Using Two Ways to Avoid Saliva Contamination
AIM: To evaluate influence of two methods to avoid saliva contamination on the survival rate of atraumatic restorations in primary molars.
- Trial name
- NCT01924611
- Testing
- Atraumatic Restorative Technique using cotton rolls, Atraumatic Restorative Technique
- Where
- Brazil
- Volunteers
- 232 people
- Sponsor
- Federal University of Paraíba
Substance-Related Disorders
Medical Office Intervention for Adolescent Drug Use
The goal of this study is to assess the efficacy of a new intervention based on motivational enhancement therapy among adolescents with a history of substance use.
- Trial name
- NCT00229983
- Testing
- Motivational Enhancement Therapy
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Boston Children's Hospital
Fracture Fixation, Internal, Distal Radius Fracture
RemeOs™ DrillPin for Fixation of Distal Radius Fractures in Children
This is a pre-market, single-arm, open-label, monocenter clinical investigation evaluating the safety and performance of the magnesium (Mg)-based bioresorbable RemeOs™ DrillPin for surgical fixation of distal radius fractures in…
- Trial name
- NCT07028541
- Testing
- Magnesium-based bioresorbable DrillPin for fixation of distal radius fractures in children
- Volunteers
- 20 people
- Sponsor
- Bioretec Ltd.
Edentulous Alveolar Ridge
Immediate Loading a Histological Study
Twelve participants with edentulous alveolar crests in the distal portion of the arches will be included in the study. At least two implant sites will be identified in each patient and will be sub-prepared with drills or sonic…
- Trial name
- NCT03714139
- Testing
- immediate loading, non implant loading
- Where
- Colombia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Supplementation, Sport
Sodium Bicarbonate Supplementation in Athletes
The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on body composition, physical capacity, as well as concentrations of the selected biochemical blood…
- Trial name
- NCT03165357
- Testing
- Sodium bicarbonate supplementation
- Where
- Poland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
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