Clinical trials: sponsored by Biruni University
Multiple Sclerosis, Rehabilitation
Music-Augmented Rhythmic Gait Training in Multiple Sclerosis
This randomized controlled trial aims to compare the effects of technology-based rhythmic gait training performed with and without music on walking performance and clinical outcomes in individuals with multiple sclerosis (MS).
- Trial name
- NCT07399262
- Testing
- Breathing and General Mobility Exercises, Music-Assisted Rhythmic Gait Training, Rhythmic Gait Training Without Music
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Biruni University
Peri-implant Mucositis
Impact of Keratinized Mucosa Augmentation on Treatment Outcomes of Peri-implant Mucositis
This study aims to observe the effects of keratinized mucosa width on peri-implant tissues by evaluating clinical and biochemical parameters.
- Trial name
- NCT06305000
- Testing
- Non-surgical treatment, Free gingival graft
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Biruni University
Periodontitis
Ozone Application in Periodontal Treatment
This clinical trial aims to evaluate the clinical, biochemical and microbiological efficacy of ozone treatment as an adjunct to nonsurgical periodontal treatment (NSPT) in periodontitis patients.
- Trial name
- NCT05971706
- Testing
- Ozone therapy using a device (Ozone DTA Ozone Generator, Denta Tec Dental AS, Norway), Non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Biruni University
Digital Technology, Healthy
A Vision-Based Characterization of Human Movement Scaling in Large-Amplitude Tasks
This pilot study investigates the feasibility of objectively quantifying movement amplitude and amplitude decay during large-amplitude exercises using RGB camera-based video analysis in healthy volunteers.
- Trial name
- NCT07387887
- Testing
- Large-Amplitude Exercise Observation and Video Recording
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Biruni University
Labor Position and Maternal Birth Experience
Standing vs. Squatting Positions During Labor
Background: Maternal position during labor is a key non-pharmacological strategy that supports physiological birth and women's active participation in the childbirth process.
- Trial name
- NCT07383181
- Testing
- Standing Position During Labor, Squatting Position During Labor
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Biruni University
Coronary Artery Disease
Drug-Coated Balloon Versus Drug-eluting Stent Angioplasty for Treatment of Chronic Total Occlusion - The DCB-CTO Trial
Chronic total occlusion (CTO) remains one of the most challenging lesions in coronary artery disease management. Percutaneous coronary intervention using drug-eluting stents is currently a standard treatment approach; however…
- Trial name
- DCB-CTO (NCT07369765)
- Testing
- Drug-Eluting Stent Group, Drug Coated Balloon Group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Biruni University
Free Gingival Graft, Wound Healing
Chitosan and i-PRF in Palatal Wound Healing
This study aims to evaluate the effects of chitosan and injectable platelet-rich fibrin (i-PRF) on wound healing at the donor site following free gingival graft (FGG) procedures.
- Conditions
- Free Gingival Graft, Wound Healing, i-PRF, Chitosan
- Trial name
- NCT07072546
- Testing
- free gingival graft + gelatin sponge, free gingival graft + chitosan, free gingival graft + chitosan and i-PRF
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Biruni University
Periodontal Diseases, Oral Health Literacy
Oral Health Literacy and Periodontal Status Among Turkish Adults
This observational cross-sectional study aimed to investigate the association between oral health literacy (OHL) and periodontal status among adult individuals attending Biruni University Faculty of Dentistry, Istanbul, Türkiye.
- Conditions
- Periodontal Diseases, Oral Health Literacy, Periodontitis, Health Behaviour
- Trial name
- NCT07341945
- Testing
- Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Biruni University
Anterior Cruciate Ligament Reconstruction Rehabilitation
Effects of Core Exercises on Balance in People With and Without ACL Surgery
The main purpose of this study is to evaluate and compare the effects of an 8-week core stabilization exercise program on balance, trunk muscle endurance, and lower body strength.
- Trial name
- NCT07328139
- Testing
- Core Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biruni University
Post Operative Pain, Apical Periodontitis
Post-operative Pain After Different Irrigation and Disinfection Methods in Single-rooted Teeth
This randomized clinical trial aimed to evaluate post-operative pain (PP) in single-rooted teeth with asymptomatic apical periodontitis following final irrigation with sonic activation systems (EDDY and EndoActivator), with and…
- Conditions
- Post Operative Pain, Apical Periodontitis, Asymptomatic Infections
- Trial name
- NCT07170098
- Testing
- EDDY sonic irrigation system, EndoActivator (EA) sonic irrigation system, 980-nm diode laser
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Suture, Complication, Gingival Recession
The Effects of Palatal Pre-sutures in Connective Tıssue Graft Surgery
Connective tissue graft operation is one of the most frequently performed surgical procedures to increase the width of the attached gingiva and to treat gingival recessions.
- Conditions
- Suture, Complication, Gingival Recession, Bleeding Hemorrhage
- Trial name
- NCT05395923
- Testing
- Suture, No Suture CTG -Control
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Biruni University
Patellar Abnormality
The Effect of Blood Flow Restriction Method in Patellar Instability
The blood flow restriction method, the effects of which have been frequently investigated in the literature in recent years, can produce muscle hypertrophy with low-intensity load and can be easily tolerated through to low…
- Trial name
- NCT05484141
- Testing
- Rehabilitation with blood blow restriction, Rehabilitation without blood flow restriction
- Volunteers
- 34 people
- Sponsor
- Biruni University
Physical Inactivity
Effects of Exercise With Different Music Frequencies
This study will explore the impact of different music frequencies applied during yoga based exercises on physical performance and cognitive status in inactive young adults.
- Trial name
- NCT07006857
- Testing
- Exercise, Low Frequency, High Frequency Music
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biruni University
Healthy
The Effects of Individualized Respiratory Exercise Device in Healthy Individuals
Respiratory exercise devices can be grouped as respiratory muscle training (RMT) devices and incentive spirometers (IS). IS can improve pulmonary ventilation using visual feedback but cannot increase respiratory muscle strength.
- Trial name
- NCT06245928
- Testing
- Individualized Respiratory Exercise Device, Threshold® IMT + Threshold™ PEP
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Biruni University
Osteoarthritis, Knee
Effect of Baduanjin on Individuals With Knee Osteoarthritis
Osteoarthritis (OA) is the most common rheumatologic disease in the world, primarily resulting in progressive cartilage destruction. It is most common in the knee joint.
- Trial name
- NCT06650865
- Testing
- Traditional Exercise Group, Baduanjin Exercise Group, Telerehabilitation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Biruni University
Parkinson Disease
Multimodal Artificial Intelligence Based Fall Risk Prediction in Parkinson's Disease
Parkinson's disease (PD) is characterized by motor symptoms such as bradykinesia, tremor, rigidity, and postural instability, often leading to gait disturbances and a high risk of falls.
- Trial name
- NCT07058714
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Biruni University
Attention Deficit Hyperactivity Disorder (ADHD)
Prediction of ADHD in Children Using Pedobarographic and Postural Data
The aim of this study is to investigate the potential of postural control and plantar pressure data in predicting Attention Deficit Hyperactivity Disorder (ADHD) in middle school students using machine learning methods.
- Trial name
- NCT07180758
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biruni University
Chronic Stroke
The Effect of Robot-assisted Gait Training in Individuals With Chronic Stroke
The aim of our study was to investigate the effect of robot-assisted gait training on quadriceps muscle thickness, balance and gait parameters in individuals with chronic stroke.
- Trial name
- NCT06746415
- Testing
- Conventional Gait Training, Robotic Gait Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Biruni University
Stroke Patients, Chronic Stroke Patients
The Effect of Task-oriented Training on Upper Extremity Motor Functions in Chronic Stroke Patients
The aim of our study was to investigate the effects of task-oriented training added to conventional rehabilitation on upper extremity muscle thickness and upper extremity motor functions.
- Trial name
- NCT06701370
- Testing
- Task Oriented Training, Conventional Rehabilitation, Upper arm ergometer
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Biruni University
Sexual Function, Over Active Bladder
The Effect Of Pelvic Floor Muscle Exercises On Sexual Life In Women With Overactive Bladder
This is a randomized controlled experimental study to determine the effect of pelvic floor muscle exercise on sexual life. The study included 64 women admitted to the Erzurum City Hospital, who consented to participate.
- Trial name
- NCT07030608
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Biruni University