Clinical trials: sponsored by Istanbul University
Pain, Acute Postoperative
Erector Spinae Plane Block Versus Thoracic Paravertebral Block in Laparoscopic Cholecystectomy
The study is planned as a single-center prospective randomized study and includes patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07149584
- Testing
- ESPB, TPVB, IV
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University
Knee Osteoarthritis
Exercise and PRP vs Exercise Alone in Patients With Knee Osteoarthritis
This study is a prospective randomized controlled study of different treatments for knee osteoarthritis and aims to investigate the efficacy of exercise combined platelet rich plasma (PRP) injection versus only exercise or only…
- Trial name
- NCT04697667
- Testing
- Exercise, PRP
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Istanbul University - Cerrahpasa
Knee Osteoarthritis, Knee Osteoarthritis (Knee OA)
Home-Based Strategies for Knee Osteoarthritis
Knee osteoarthritis (KOA) is a common chronic joint condition leading to pain, functional limitations, and reduced quality of life.
- Trial name
- NCT07212647
- Testing
- Home Exercise Group, Topical Therapy Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 83 people
- Sponsor
- Istanbul University - Cerrahpasa
Scoliosis
Scoliosis and Functional Outcomes in Children With Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that may affect musculoskeletal development and posture in children.
- Trial name
- NCT07433894
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dental Pulp Disease, Pulp Necrosis
Diagnostic Accuracy of Cold, Heat, and Electric Pulp Tests
The goal of this observational study is to evaluate the diagnostic accuracy of cold, heat, and electrical pulp tests in adults with teeth suspected of requiring endodontic treatment. The main questions it aims to answer are: 1.
- Conditions
- Dental Pulp Disease, Pulp Necrosis, Pulpitis - Irreversible
- Trial name
- NCT07434622
- Testing
- Pulp Sensibility Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people
- Sponsor
- Istanbul University
Infantile Colics
The Effect of Thermal Heat Application on Colic in Infants
This study is a randomized controlled experimental trial designed to evaluate the effectiveness of thermal heat applications-specifically cherry pit pillows and warm towels-on reducing colic symptoms in infants aged 0-3 months.
- Trial name
- NCT07435948
- Testing
- Cherry Pit Pillow Application, Warm Towel Application
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa
Heart Failure
Echocardiography-Based Predictors of Outcomes in Hospitalized Patients With Decompensated Heart Failure (ECHO-DECOMP)
Acute decompensated heart failure is a leading cause of hospitalization and is associated with high morbidity and mortality. Early risk stratification in this population is crucial for guiding treatment strategies and predicting…
- Trial name
- ECHO-DECOMP (NCT07439159)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Disease
Relationship Between Coronary CT Angiography Findings and Prognosis Of Patients Undergoing PCI
Researchers at Cerrahpaşa Medical School in Istanbul are studying how a heart imaging test called coronary CT angiography can help improve care for people with coronary artery disease.
- Trial name
- NCT07051473
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Femur Fracture, Periprosthetic Fracture of Hip
Dose-Response Association Between Cerclage Wire Number and Infection Risk
The purpose of this dual-center retrospective study is to investigate the relationship between the number of metallic cerclage wires used in femoral fracture surgery and the risk of developing deep infections.
- Conditions
- Femur Fracture, Periprosthetic Fracture of Hip, Periprosthetic Fracture of the Femur, Surgical Site Infection (SSI)
- Trial name
- C-INFECT (NCT07434258)
- Testing
- 1 Metallic Cerclage Wiring, 2 metalic cerclage wire, 3 metalic cerclage wire
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Maternal Pushing Techniques, Perineal Trauma
Vocalization and Spontaneous Pushing in the Second Stage of Labor
The second stage of labor, defined as the period from full cervical dilatation to fetal birth, is a critical phase in which maternal pushing techniques may significantly affect maternal and neonatal outcomes (1-5).
- Conditions
- Maternal Pushing Techniques, Perineal Trauma, Maternal Fatigue, Labor
- Trial name
- NCT07316348
- Testing
- The vocalization straining technique will be used.
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Cardiovascular Diseases, Cardiovascular Complication
The Effect Of Perioperative Results On Mortality In Coronary Artery Bypass Surgery
Coronary artery bypass grafting (CABG) is one of the most common heart surgeries. Most patients are elderly with comorbidities that affect morbidity and mortality rates. Even in developed countries mortality rate is 1.9-5.3%.
- Conditions
- Cardiovascular Diseases, Cardiovascular Complication, Anesthesia
- Trial name
- NCT06812624
- Testing
- There is no intervention in this study.
- Where
- Turkey (Türkiye)
- Volunteers
- 485 people
- Sponsor
- Istanbul University - Cerrahpasa
Horticultural Therapy, Loneliness
The Effect of Horticultural Therapy on Loneliness and Life Satisfaction in Elderly Adults Living in Nursing Home
Loneliness in elderly individuals increases with age and negatively affects individuals by decreasing life satisfaction. In recent years, horticultural therapy is a type of therapy that has developed and is added routine care of…
- Conditions
- Horticultural Therapy, Loneliness, Satisfaction, Personal, Aging
- Trial name
- NCT06311825
- Testing
- Horticultural Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Apneic Oxygenation, Endolarengeal Surgery
Oxygen Reserve Index (ORi) in Identifying Desaturation
This randomized clinical trial investigates whether Oxygen Reserve Index (ORi) monitoring enables earlier detection of impending hypoxemia compared with conventional pulse oximetry during apneic intermittent ventilation in adult…
- Conditions
- Apneic Oxygenation, Endolarengeal Surgery, Oxygen Reserve Index
- Trial name
- NCT07415161
- Testing
- oxygen monitoring techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Thyroidectomy, Postoperative Neck Pain
Neck Exercises After Thyroid Surgery
Postoperative neck pain is common after thyroidectomy and may impair early recovery. This prospective randomized controlled study aimed to evaluate the effects of postoperative neck range-of-motion (ROM) and isometric…
- Conditions
- Thyroidectomy, Postoperative Neck Pain, Quality of Life (QOL), Cervical Range of Motion
- Trial name
- NCT07415174
- Testing
- Postoperative Neck Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Istanbul University - Cerrahpasa
Breastfeeding, Skin to Skin Contact
Effect of Combined Skin-to-Skin Contact and Kangaroo Care on Breastfeeding and Bonding in Cesarean-Born Newborns
This randomized controlled study aims to evaluate the effect of consecutive skin-to-skin contact applied by the mother and father on breastfeeding parameters and parent-infant bonding in babies born by cesarean section.
- Conditions
- Breastfeeding, Skin to Skin Contact, Cesarean Birth, Kangaroo Care
- Trial name
- SSC-CS (NCT07410754)
- Testing
- Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment
"Ultrasound Measures and Clinical Outcomes in Healthy Individuals, Mild and Moderate Carpal Tunnel Syndrome Patients"
"This study aims to investigate ultrasonographic parameters of the median nerve in healthy individuals and patients with mild and moderate carpal tunnel syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment, Electrophysiologic Study, Ultrasound
- Trial name
- NCT07408596
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Ankle Instability, Healthy Controls
Acute Effect of Graded Motor Imagery on Ankle Rehabilitation: A Pilot Study
The primary aim of this study is to evaluate the immediate and short-term effects of the Graded Motor Imagery (GMI) method on individuals with chronic ankle instability (CAI).
- Trial name
- NCT07376915
- Testing
- graded motor imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Pulmonary Complications, Postoperative Pulmonary Atelectasis
Evaluation of the Effect of Perioperative Recruitment Maneuver Practice on Lung Ultrasound Score and Mechanical Power in Pediatric Patients
Pulmonary atelectasis is common during general anesthesia and increases the risk of hypoxemia, especially in pediatric patients. PEEP and recruitment maneuvers (RM) are effective in preventing atelectasis.
- Conditions
- Postoperative Pulmonary Complications, Postoperative Pulmonary Atelectasis, Pediatric Surgery
- Trial name
- LUS RM PEEP (NCT07294560)
- Testing
- recruitment maneuver, right and left lateral decubitus position recruitment maneuvers
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Istanbul University - Cerrahpasa
Maternal Stress, Fetal Well-Being
The Effect of Watching Cat Videos on Non-Stress Test Results And Stress Parameters in Pregnant Women
Pregnancy is a period in which women are physiologically and psychologically vulnerable, and the stress experienced can affect both maternal mental health and fetal well-being.
- Trial name
- NCT07332039
- Testing
- Group watching cat videos, Non-Video Watching Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pes Planus
Biofeedback-Assisted Short Foot Exercises in Flexible Flatfoot
The goal of this clinical trial is to compare the effects of biofeedback-assisted short foot exercises and traditional short foot exercises in individuals with flexible pes planus.
- Trial name
- NCT07286773
- Testing
- Biofeedback assisted exercises, Supervised exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
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