Clinical trials: sponsored by Istanbul University
Video-assisted Thoracoscopic Surgery (VATS), Thoracic Surgery, Video Assisted
Target-Controlled Infusion (TCI) vs Inhalational Anesthesia in Video-Assisted Thoracoscopic Surgery (VATS)
This study is designed as a prospective observational cohort to evaluate recovery after video-assisted thoracoscopic surgery (VATS).
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Thoracic Surgery, Video Assisted, Postoperative Recovery, General Anesthesia
- Trial name
- TCI-INHALE (NCT07288099)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Major Depression Moderate, Major Depression Severe
EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT
This study aims to investigate the neurophysiological and inflammatory changes associated with electroconvulsive therapy (ECT) in older age patients diagnosed with Major Depressive Episode, Major Depression, and Bipolar Disorder…
- Conditions
- Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression With Panic Attacks
- Trial name
- NCT07740694
- Testing
- Electroconvulsive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment
Turkish Adaptation of the CTS-6 Evaluation Tool: A Validation and Reliability Study
The purpose of this study is to develop the Turkish version of the CTS-6 Evaluation Tool and to comprehensively assess its validity and reliability in the Turkish population.
- Conditions
- Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment, Peripheral Nerve Disease, Peripheral Nerve Disorder
- Trial name
- NCT07420049
- Testing
- CTS-6 Evaluation Tool
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Frozen Shoulder, Adhesive Capsulitis
Effect of Hormone Replacement Therapy on Physiotherapy Outcomes in Postmenopausal Women With Frozen Shoulder
The purpose of this study is to compare the effects of a physiotherapy program on pain levels, shoulder range of motion, functional status, pain catastrophizing, perceived change, sleep quality, and quality of life in…
- Conditions
- Frozen Shoulder, Adhesive Capsulitis, Adhesive Capsulitis of the Shoulder, Hormone Replacement Therapy, Post-Menopausal
- Trial name
- NCT07736027
- Testing
- Standardized Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Heart Failure
Investigation of the Effect of Inspiratory Muscle Training and Dual-Task Inspiratory Muscle Training on Cognitive Functions in Heart Failure
The goal of this clinical trial is to evaluate whether dual-task inspiratory muscle training (IMT) is effective in improving cognitive and functional outcomes in adults with heart failure.
- Trial name
- NCT07581587
- Testing
- Dual-Task IMT, IMT
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University - Cerrahpasa
Post-activation Performance Enhancement and Repeated Sprint Performance in Trained Soccer Players
Effects of Heavy Back-Squat PAPE on Jump and Repeated Sprint Performance in Trained Soccer Players
This study examined whether performing heavy back squats before exercise affects jumping ability and repeated sprint performance in trained soccer players.
- Trial name
- NCT07736209
- Testing
- Heavy Back-Squat PAPE Protocol, Standardized Warm-Up Control Condition
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Breech Birth Maneuvers, Virtual Reality (VR) Technology
Virtual Reality Technology-Based Breech Birth Maneuver Training
Midwifery education is a comprehensive process aimed at equipping students with advanced theoretical knowledge, clinical decision-making abilities, and complex psychomotor skills necessary to promote and protect maternal and…
- Trial name
- NCT07732998
- Testing
- Virtual Reality, Conventional Slide-Based Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Trigger Finger
Betamethasone vs Dextrose Injections in Trigger Finger
This study aims to compare the effectiveness of ultrasound-guided betamethasone and dextrose injections in patients with trigger finger.
- Trial name
- NCT07681804
- Testing
- Betamethasone, Dextrose Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University - Cerrahpasa
Bone Neoplasms, Soft Tissue Neoplasms
Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue Cancer
This prospective observational study will follow adults who are scheduled for a clinically indicated biopsy because of a suspected solid tumor involving bone or soft tissue.
- Conditions
- Bone Neoplasms, Soft Tissue Neoplasms, Anxiety, Stress, Psychological
- Trial name
- BIOPSY-STRESS (NCT07727434)
- Testing
- Routine Diagnostic and Treatment Pathway
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Prostate Cancer, Lung Protective Ventilation
Evaluating Respiratory Effects of Driving Pressure Guided Mechanical Ventilation Using Electrical Impedance Tomography in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Robot-Assisted Laparoscopic Radical Prostatectomy is a method increasingly used for prostate cancer due to fewer complications, morbidity, and mortality compared to other methods.
- Conditions
- Prostate Cancer, Lung Protective Ventilation, Postoperative Pulmonary Complications
- Trial name
- NCT06540794
- Testing
- PEEP TITRATION
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University
Stroke, Hemiplegia
Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke.
- Conditions
- Stroke, Hemiplegia, Chronic Stroke
- Trial name
- NCT07725211
- Testing
- Neurodevelopmental Treatment, High-Repetition Task-Oriented Training, High-Intensity Gait Training
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University - Cerrahpasa
Distal Radius Fracture
Effect of Whole Body Vibration on Rehabilitation in Distal Radius Fractures
This study is a randomized controlled clinical trial designed to evaluate the effects of whole body vibration (WBV) added to conventional rehabilitation on functional and sensorimotor recovery in patients with conservatively…
- Trial name
- WBV-DRF (NCT07723456)
- Testing
- Whole-Body Vibration Therapy, Conventional Rehabilitation Exercise Program
- Volunteers
- 66 people
- Sponsor
- Istanbul University
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Comparison of Synchronous and Asynchronous Action Observation Therapy in Children With Cerebral Palsy
The aim of this study is to compare the effects of synchronous and asynchronous action observation therapy (AOT) on balance, gait, and functional capacity in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy, Neurodevelopmental Disorder (Diagnosis)
- Trial name
- NCT07114731
- Testing
- Synchronous Action Observation Therapy, Asynchronous Action Observation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Istanbul University - Cerrahpasa
Autism Spectrum Disorder (ASD)
Exercise Efficacy on Autism Spectrum Disorder
The goal of this clinical trial is to learn if regular exercise intervention may improve the health status of the participants diagnosed with autism spectrum disorder, ages between 5-13 years old.
- Trial name
- NCT06831188
- Testing
- daily life exercise group, specific type exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Pediatric Regional Anesthesia, Retrolaminar Block
Retrolaminar Plane Block Versus Anterior Quadratus Lumborum Block in Pediatric Urogenital Surgery
Effective control of postoperative pain following pediatric lower urogenital surgery is important for enhancing recovery and reducing opioid requirements.
- Conditions
- Pediatric Regional Anesthesia, Retrolaminar Block, Pediatric Postoperative Pain
- Trial name
- NCT07711496
- Testing
- Anterior Quadratus Lumborum Block, Retrolaminar Block
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Istanbul University - Cerrahpasa
Nursing Education
Impact of Innovation Workshop-Integrated Outcome-Based Education on Critical Thinking and Innovation Skills Among Nursing Students: A Mixed-Methods Study
This mixed-methods study aims to evaluate the effectiveness of workshop-integrated Outcome-Based Education (OBE) implemented within a Project Planning Course on nursing students' critical thinking motivation and individual…
- Trial name
- NCT07710378
- Testing
- Workshop-Integrated Outcome-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Adhesive Capsulitis, Corticosteroid Injection
Pericapsular vs Intra-Articular Injection in Adhesive Capsulitis
Adhesive capsulitis is a common and disabling shoulder disorder characterized by progressive pain and restricted active and passive range of motion, leading to significant limitations in daily activities and reduced quality of…
- Trial name
- NCT07710651
- Testing
- Betamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Distal Radius Fracture
Below-Elbow Versus Initial Above-Elbow Casting for Distal Radius Fractures
The goal of this clinical trial was to compare two casting strategies for adults with a broken wrist, also called a distal radius fracture.
- Trial name
- NCT07704879
- Testing
- Below-Elbow Cast Immobilization, Initial Above-Elbow Cast Followed by Below-Elbow Cast
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Istanbul University
Muscle Hypotrophy, Exercise Performance
Resistance Training Adaptations and Caffeine Intake
This parallel-group, randomized, double-blind, placebo-controlled trial investigates the effects of three different caffeine supplementation strategies on resistance training-induced adaptations in 120 caffeine-naive, inactive…
- Conditions
- Muscle Hypotrophy, Exercise Performance, Muscle Strength, Adaptation
- Trial name
- NCT07410195
- Testing
- Caffeine (Constant Daily Dose), Caffeine (Escalating Dose), Caffeine (Training Days Only)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Membranous Nephropathy, Membranous Nephropathy - PLA2R Induced
Analysis of T- and B-Cell Subpopulations in Membranous Nephropathy
The aim of this observational study is to provide analysis of T and B lymphocyte subgroups in peripheral blood samples of patients with primary membranous nephropathy (MN).
- Conditions
- Membranous Nephropathy, Membranous Nephropathy - PLA2R Induced, Membranous Nephropathy - THSD7A Induced
- Trial name
- NCT05894512
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Istanbul University
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