Clinical trials: sponsored by The Hong Kong Polytechnic University
Behavioral Self-monitoring and Metacognitive Reflection
A Randomized Controlled Ecological Momentary Intervention to Improve Digital Self-Regulation and Well-Being
The primary objective of this study is to examine whether an ecological momentary intervention (EMI), combining behavioral self-monitoring (screen time screenshot uploads) and structured reflection, can enhance metacognitive…
- Trial name
- NCT07511374
- Testing
- Ecological momentary intervention
- Where
- Hong Kong
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Sarcoma
Information-providing Chatbot
This study aims to develop and examine the feasibility and preliminary effectiveness of an AI-based sarcoma chatbot building on ChatGPT (ASCC) to address the information needs of sarcoma patients.
- Trial name
- NCT07505732
- Testing
- ASCC (sarcoma-specific AI chatbot), Routine Clinical Care
- Volunteers
- 78 people
- Sponsor
- The Hong Kong Polytechnic University
Alcohol Use Disorder, Alcohol Abstinence
Feasibility of Telephone-based Acceptance and Commitment Therapy in Hong Kong Chinese Young Adults With Alcohol Use Disorder: A Pilot Study
Objective: The proposed study aims to develop a protocol of telephone-based Acceptance and Commitment Therapy (ACT) for Alcohol Use Disorder (AUD) and examine the feasibility of implementing such intervention among the Hong Kong…
- Trial name
- NCT07501130
- Testing
- ACT, Social support
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Glaucoma Open-Angle
Combined Non-Invasive Brain and Visual Stimulation for Vision Improvement
Glaucoma is a complex disease that can result in progressive vision loss. It is the second leading cause of blindness, accounting for 23% of permanent blindness in Hong Kong.
- Trial name
- NCT07486323
- Testing
- NIBS, VTS, NIBS+VTS
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- The Hong Kong Polytechnic University
Interprofessional Education, Serious Games
Impacts of Immersive Virtual Reality (iHealthEd-IVR) and a Mobile Online Game (V-Care) on Interprofessional Education
The goal of this randomised controlled trial is to compare the effectiveness of IVR and game-based learning in Interprofessional education (IPE), with significant implications for IPE delivery.
- Trial name
- NCT07474701
- Testing
- IVR group, web-based group
- Where
- Hong Kong
- Volunteers
- 271 people
- Sponsor
- The Hong Kong Polytechnic University
Cancer
DST in Reducing Depressive Symptoms, Enhancing Self-esteem, and Promoting Quality of Life Among CCSs
This study aims to examine the effectiveness of Digital storytelling (DST) in reducing depressive symptoms, enhancing self-esteem, and promoting quality of life among Chinese survivors of childhood cancer.
- Trial name
- NCT07052110
- Testing
- Digital storytelling
- Where
- Hong Kong
- Volunteers
- 248 people
- Sponsor
- The Hong Kong Polytechnic University
Heart Failure (HF)
Effect of the Home-based Digital-assisted Dyadic Tai Chi (HDTC) Training Program Among Sedentary Individuals With HF and Their Caregivers: a Randomized Controlled Trial
The full scale RCT aims to assess the effectiveness of the HDTC training program in improving functional capacity, cardiac function and secondary outcomes among sedentary chronic heart failure (CHF) individuals, while…
- Trial name
- NCT06876441
- Testing
- HDTC training program, Usual Care Group
- Where
- China
- Volunteers
- 256 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Digital Mirror Therapy in Stroke Rehabilitation
Background: While conventional mirror therapy is a Level A recommended rehabilitation for poststroke upper extremity recovery, digital mirror therapy-enabled by augmented reality and computer vision-offers a promising alternative…
- Trial name
- NCT07460128
- Testing
- digital mirror therapy, conventional mirror therapy
- Where
- 2 sites in Hong Kong
- Volunteers
- 44 people
- Sponsor
- The Hong Kong Polytechnic University
Developmental Disabilities
ACT Dad's Power: Feasibility RCT for Fathers of Children With Special Needs
Objective: (1) To examine the feasibility of proceeding to a future definitive RCT of ACT in Hong Kong Chinese fathers rearing children with special needs.
- Trial name
- NCT07459010
- Testing
- VR-based ACT, Health Talks and Simple Social Support
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Depression
Effects of an Innovative TCM-based Tui Jing Therapy on Psychological and Neurophysiological Functions in Depression
Background: Mental disorders are recognized as a major cause of disability and disease burden across the lifespan. Gua Sha is believed to improve mental health and sleep quality significantly.
- Trial name
- TJ (NCT07449676)
- Testing
- manual therapy: Tui Jing therapy
- Where
- Hong Kong
- Volunteers
- 64 people
- Sponsor
- The Hong Kong Polytechnic University
Sarcopenic Obesity
Dietary Programme and Exercise Training in Combination or Separately on Managing Sarcopenic Obesity in Older Adults
Sarcopenic obesity (SO) has synergistic detrimental effects on elderlies' health. It greatly increases the risk of cardio-metabolic diseases, physical impairment, institutionalization, and mortality when compared with sarcopenia…
- Trial name
- NCT05734755
- Testing
- The Individualized Dietary Behavioural Change Programme (IDBC), The Exercise Training
- Where
- Hong Kong
- Volunteers
- 380 people
- Sponsor
- The Hong Kong Polytechnic University
Alcohol Abstinence
The Use of Telephone-based ACT for Quitting Alcohol in the Young Population With Hazardous or Harmful Alcohol Use.
Objectives: To investigate the effectiveness of a telephone-based acceptance and commitment therapy (ACT) in assisting young adult drinkers with hazardous or harmful alcohol use (HH drinkers) to quit drinking.
- Trial name
- NCT07450248
- Testing
- Telephone-based ACT, Telephone-based social support
- Volunteers
- 288 people
- Sponsor
- The Hong Kong Polytechnic University
Smoking Cessation, Schizophenia Disorder
Effects of Smoking on Network Connectivity in Patients With Schizophrenia Symptoms in Scz Patients
The prevalence of smoking among people with schizophrenia (SCZ) is substantially higher at 54% to 90% (McClave et al., 2010). About half of all deaths amongst people with scz are attributed to smoking-related diseases and cancer…
- Trial name
- ACT (NCT07441928)
- Testing
- Acceptance and Commitment Therapy (ACT-SC), 5A model (Ask, Assess, Advice, Assist & Arrange) smoking cessation intervention (5A-SC)
- Where
- 5 sites in Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Ophthalmology, Large Language Models
A Multimodal AI Agent for Ophthalmic Clinical Decision Support
This study is a multicenter randomized controlled trial evaluating the effectiveness and safety of EyeAgent, a multimodal artificial intelligence (AI) agent designed to assist ophthalmologists in clinical decision-making.
- Conditions
- Ophthalmology, Large Language Models, AI Agent, Eye Disease
- Trial name
- NCT07401459
- Testing
- EyeAgent AI system
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Stroke
taVNS Combined With TENS on Motor Function in Stroke
the current study is a Blinded Randomised Controlled Trial investing the effectiveness of Combining Transcutaneous Vagus Nerve Stimulation with Peripheral Nerve Stimulation on Upper Limb Motor Function in People with Stroke
- Trial name
- NCT07425756
- Testing
- transcutaneous auricular vagus nerve stimulation, transcutaneous electrical nerve stimulation, task-oriented training
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
AMD - Age-Related Macular Degeneration
Repeated Low-Level Red-Light Therapy in Dry Age-Related Macular Degeneration
This prospective, double-blind, randomized controlled trial aims to evaluate the efficacy and safety of repeated low-level red-light (RLRL) therapy in patients with dry age-related macular degeneration (AMD).
- Trial name
- NCT07409389
- Testing
- RLRL device
- Where
- China
- Volunteers
- 94 people
- Sponsor
- The Hong Kong Polytechnic University
Knee Osteoarthritis
Heart Rate Variability Guided Physical Activity and Exercise Prescription in Individuals With Knee Osteoarthritis
The aim of this trial is to conduct a 12-week randomised controlled trial comparing an HRV-guided home exercise program with traditional home exercise program for individuals with knee osteoarthritis (KOA), followed by 24-week…
- Trial name
- HOPE-OA (NCT07391449)
- Testing
- HRV-guided home exercise prescription, Traditional Home Exercise
- Where
- Hong Kong
- Volunteers
- 240 people
- Sponsor
- The Hong Kong Polytechnic University
Healthy Participants Study
Positive Psychology - Based EMl for Enhancing Well-Being
This study aims to evaluate the acceptability and effectiveness of a positive psychology-based ecological momentary intervention (EMI) for enhancing well-being in college students.
- Trial name
- NCT07406880
- Testing
- Ecological Momentary Intervention, Active Control
- Where
- Hong Kong
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS)
Transcranial Direct Current Stimulation in Children With Autism Spectrum Disorder
Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade.
- Conditions
- Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS), Electroencephalography
- Trial name
- NCT06880159
- Testing
- tDCS with computerized cognitive training
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Pediatric Functional Dyspepsia
Parent-administered Pediatric Tuina Versus Routine Care for Pediatric Functional Dyspepsia
Title: Parent-administered pediatric tuina with routine care versus routine care alone for pediatric functional dyspepsia: a pilot randomized controlled trial Background: Pediatric functional dyspepsia (PFD) is a common…
- Trial name
- NCT07369687
- Testing
- parent-administered pediatric tuina
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University