Clinical trials: sponsored by University of Bern
Cerebral Palsy
Swiss Cerebral Palsy Registry
The Swiss-CP-Reg is a national patient registry that collects information on diagnosis, symptoms, treatment and follow-up of patients with cerebral palsy (CP) in Switzerland.
- Trial name
- Swiss-CP-Reg (NCT04992871)
- Where
- 12 sites in Switzerland
- Volunteers
- 15,000 people
- Sponsor
- University of Bern
Partial Edentulism Class 3
Immediate Loading in Single Tooth Implants
The planned study is designed to provide evidence for the application of early implant placement with partial bone-healing and either an immediate or an early restoration/ loading protocol.
- Trial name
- NCT05409287
- Testing
- Immediate Implant Loading, Early Implant Loading
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Bern
Medication Review, Primary Care
A Swiss Interprofessional Network for Reviewing Inappropriate Medication in Primary Care
The aim of the SINERGIC pilot study is to assess the feasibility in the Swiss context of implementing interprofessional medication reviews between GP and pharmacists, as part of a shared decision-making process with patients.
- Trial name
- SINERGIC (NCT07283055)
- Testing
- Medication review
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Bern
Pandemic, COVID-19, Infections
Bern, Get Ready (BEready) Cohort Study for Pandemic Preparedness
The BEready project aims to find out how people in the Canton of Bern can be helped to be more prepared for the next pandemic. BEready wants to understand how infections spread among people as well as between people and animals.
- Conditions
- Pandemic, COVID-19, Infections, Zoonoses, Epidemic Disease
- Trial name
- BEready (NCT06739499)
- Where
- Switzerland
- Volunteers
- 2,157 people, healthy volunteers welcome
- Sponsor
- University of Bern
Type 1 Diabetes (T1D)
GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes
Blood glucose management in type 1 diabetes (T1D) remains a challenge, with only ~30% of adults within the recommended consensus guidelines.
- Trial name
- AID-JUNCT (NCT06630585)
- Testing
- Tirzepatide
- Where
- 3 sites in Switzerland
- Volunteers
- 42 people
- Sponsor
- University of Bern
Suicide, Attempted, Suicidal Ideation
Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy Attempted Suicide Short Intervention Program (ASSIP) on Neuropsychological Correlates and Psychological Process Factors - Project 3
The present study consists of 3 projects in total. It aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the feasibility and cost-effectiveness of ASSIP flex.
- Conditions
- Suicide, Attempted, Suicidal Ideation, Feasibility, Cost-effectiveness
- Trial name
- NePsyAssip HT (NCT06322199)
- Testing
- ASSIP (Attempted Suicide Short Intervention Program) flex
- Where
- 4 sites in Switzerland
- Volunteers
- 119 people
- Sponsor
- University of Bern
Dental Implant Failure
Variables for Long-term Success in Implant Dentistry
The aims of the present retrospective 25-year study of a sample of 459 patients with 753 sandblasted and acid-etched (SLA) titanium oral implants are: to assess the clinical parameters at SLA implants after 25 years in function…
- Trial name
- NCT06599320
- Testing
- Oral rehabilitation with dental implants
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Bern
Dental Implant Failed, Prosthesis Failure
Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever Extension
To report the clinical and radiographic outcomes of implant-supported fixed dental prostheses with full-ceramic cantilever extensions (FDPCs) after a function time ≥ 12 months.
- Conditions
- Dental Implant Failed, Prosthesis Failure, Peri-Implantitis
- Trial name
- NCT05676268
- Testing
- Implant-supported fixed dental prostheses with cantilever extension
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Inhibitory Control, Self Efficacy
Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy Attempted Suicide Short Intervention Program (ASSIP) on Neuropsychological Correlates and Psychological Process Factors - Project 2
The present study consists of 3 projects in total and aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the effects and feasibility of ASSIP Home Treatment.
- Conditions
- Inhibitory Control, Self Efficacy, Suicide Ideation, Suicide, Attempted
- Trial name
- NePsyAssip HT (NCT06263712)
- Testing
- Attempted Suicide Short Intervention Program (ASSIP), Standard of care plus resource interview group (STAR)
- Where
- Switzerland
- Volunteers
- 156 people
- Sponsor
- University of Bern
Inhibitory Control, Locus of Control
Neuropsychological Patterns of Suicide Ideators and Suicide Attempters
The present study consists of 3 projects in total and aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the effects and feasibility of ASSIP Home Treatment.
- Conditions
- Inhibitory Control, Locus of Control, Self Efficacy, Suicide, Attempted
- Trial name
- NePsyAssip HT (NCT06248268)
- Testing
- (Neuro-)psychological assessment
- Where
- Switzerland
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Bern
SMA, DMD
Swiss Registry for Neuromuscular Disorders
The Swiss Patient Registry for DMD/BMD and SMA was launched in 2008 in order to give Swiss patients access to new therapies. It was founded with the financial support of several patient organizations and research foundations.
- Conditions
- SMA, DMD, BMD, IMD
- Trial name
- Swiss-Reg-NMD (NCT05102916)
- Where
- 19 sites in Switzerland
- Volunteers
- 2,000 people
- Sponsor
- University of Bern
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 5 of 7)
NOTE: This is the fifth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919189
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 6 of 7)
NOTE: This is the sixth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919163
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Breast Cancer Survivors, Colorectal (Colon or Rectal) Cancer Survivors
The Development of MASLD Among Survivors of Breast or Colorectal Cancer
A metabolic issue is a condition where the body has problems with converting food into energy, using energy or storing energy properly.
- Conditions
- Breast Cancer Survivors, Colorectal (Colon or Rectal) Cancer Survivors, MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis)
- Trial name
- EVALUATE (NCT07280143)
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Bern
Diabetes Mellitus
The Daytime Circadian Rhythm in Exhaled Volatile Organic Compounds in People Living Without and Diabetes
Exhaled volatile organic compounds will be measured during daytime with the goal to identifying circadian variability. The study incudes three subgroups: people without diabetes, people with type 1 diabetes, and people with type…
- Trial name
- VOCircle (NCT05984979)
- Testing
- Standardized meal
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bern
Primary Ciliary Dyskinesia, Kartagener Syndrome
The Ear-Nose-Throat (ENT) Prospective International Cohort of PCD Patients (EPIC-PCD)
The Ear-Nose-Throat (ENT) Prospective International Cohort of patients with Primary Ciliary Dyskinesia (EPIC-PCD) is a prospective observational clinical cohort study, set up as a multinational multi-centre study.
- Trial name
- EPIC-PCD (NCT04611516)
- Where
- Switzerland
- Volunteers
- 1,000 people
- Sponsor
- University of Bern
Primary Ciliary Dyskinesia
Living With Primary Ciliary Dyskinesia (Living With PCD)
Living with PCD (formerly COVID-PCD) is a participatory research project that aims to answer emerging questions about primary ciliary dyskinesia (PCD) in order to improve the health and quality of life of people with PCD.
- Trial name
- NCT04602481
- Where
- Switzerland
- Volunteers
- 1,500 people
- Sponsor
- University of Bern
Rare Diseases
Swiss Rare Disease Registry (SRDR)
The SRDR is a national registry that records rare diseases in people of any age who live in Switzerland. It serves as a platform for scientists, health professionals, affected people, and politicians.The SRDR aims to collect…
- Trial name
- SRDR (NCT05179863)
- Where
- 20 sites in Switzerland
- Volunteers
- 500,000 people
- Sponsor
- University of Bern
Hiv
HIV-1 Subtype-specific Drug Resistance in Patients Failing Dolutegravir (DTG) Based Regimen
This is a prospective observational study enrolling People Living with HIV (PLHIV) who are on a Dolutegravir-based AntiRetroviral Treatment (ART) regimen and experiencing virologic failure.
- Trial name
- DTG-Resist (NCT06285110)
- Where
- 22 sites in Argentina, Brazil and 14 more
- Volunteers
- 1,103 people
- Sponsor
- University of Bern
Primary Ciliary Dyskinesia, Kartagener Syndrome
International Primary Ciliary Dyskinesia Cohort
The iPCD Cohort is an international cohort that assembles available retrospective datasets and prospectively newly collected clinical and diagnostic data from patients suffering from primary ciliary dyskinesia (PCD) worldwide, to…
- Trial name
- iPCD (NCT03517865)
- Where
- Switzerland
- Volunteers
- 3,400 people
- Sponsor
- University of Bern