Clinical trials: sponsored by University of Miami
TKA, THA
Binaural Beats for Postoperative Pain and Anxiety Reduction
To deliver a 30-minute binaural beats audio intervention in PACU and collect pain and anxiety outcomes immediately following surgery, and 4 hours following surgery completion in adults undergoing ambulatory total knee…
- Conditions
- TKA, THA, Anxiety, Binaural Beats
- Trial name
- NCT07437469
- Testing
- Binaural Beats Audio Intervention, Music of Choice
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
SCI - Spinal Cord Injury
Food Intake and Thermogenesis in High Spinal Cord Injury
The purpose of this research is to determine the effects of food on cardiovascular and metabolic health in men with and without spinal cord injury (SCI).
- Trial name
- NCT07103993
- Testing
- Low meal condition, Moderate meal condition, High meal condition
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Miami
Spinal Cord Injuries, Obesity
Spinal Cord Injury Model Systems (SCIMS) - Education Module
The purpose of this study is to find out if receiving education regarding increased risks of cardiometabolic disease helps subjects understand these risks and how these risks participants' health.
- Conditions
- Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
- Trial name
- NCT06003686
- Testing
- PVA Consumer Guide, WebMD
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Miami
Emotions, Anhedonia
Geolocation Positional System (GPS) Experience
The purpose of this study is to use smartphone technology to capture individual location emotional and cognitive data, to examine how real-world behaviors thoughts, emotions, and brain activity are related to one another.
- Conditions
- Emotions, Anhedonia, Depression
- Trial name
- NCT05991713
- Testing
- Modifying Exploration
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Activity, Motor
Velocity-Loss Training and Parkinson's Disease
This study will compare the effects of velocity-loss resistance training at 10% and 30% velocity loss thresholds on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.
- Trial name
- NCT07840508
- Testing
- 10% Velocity-Loss Threshold Resistance Training, 30% Velocity-Loss Threshold Resistance Training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Miami
Type 2 Diabetes, Type 2 Diabetes (T2DM)
PLEASURE (Pleasing Lovers, Efficacy, Arousal, Satisfaction, and Uptake Research on Eroxon)
The purpose of this research study is to look at whether Eroxon® gel when used together with tadalafil, may help improve erectile function in men ages 18 to 40 who have type 2 diabetes.
- Trial name
- NCT07636161
- Testing
- Eroxon®, tadalafil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Recurrent Endometrial Cancer
Pembrolizumab and Lenvatinib in Mismatch Repair Proficient Recurrent Endometrial Cancer After Progression on or Following First-Line Immunotherapy Maintenance
The purpose of this study is to determine the efficacy and safety of Pembrolizumab in combination with Lenvatinib in recurrent, mismatch repair-proficient endometrial cancer after failure of first-line therapy with a…
- Trial name
- NCT07594015
- Testing
- Pembrolizumab, Lenvatinib
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Miami
Crohn's Disease, Active, Crohn's Disease (CD)
Tailored Anti-Inflammatory American Diet for Patients With Crohn's Disease
The purpose of this study is to test the effect of an anti-inflammatory diet tailored for patients living in the United States with Crohn's Disease (CD) on clinical symptoms and disease inflammation and to identify biomarkers of…
- Conditions
- Crohn's Disease, Active, Crohn's Disease (CD), Diet Interventions
- Trial name
- NCT07671872
- Testing
- Catered Anti-Inflammatory Diet, Diet Guidance for Usual Diet
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Miami
HER2-positive Metastatic Breast Cancer, Stage IV Breast Cancer
Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer
The purpose of this preliminary research study is to see if patients discontinuing maintenance Herceptin and/or other anti-HER-2 treatments with monitoring in addition to radiologic imaging and routine blood work will stay in…
- Trial name
- Free-HER (NCT05959291)
- Testing
- Discontinuation of Anti-HER-2 Maintenance Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Breast Cancer, Prostate Cancer
Precise Oncology Interventions in Nutrition and Training (OnPoint)
The purpose of this study is to see if survivors of breast, prostate, colorectal or lymphoma cancer who receive a personal referral to a targeted nutrition and exercise program will be able to eat a healthier diet and be more…
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer, Lymphoma
- Trial name
- OnPoint (NCT06534918)
- Testing
- Fitbit, Nutrition Course: Group Sessions, Physical Activity Program: Group Sessions
- Where
- United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Miami
Osteoarthritis, Vitamin D Deficiency
Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA)
The purpose of this study is being conducted to determine whether correcting low levels of vitamin D with a single high-dose supplement reduces complications after the participant's primary TJA.
- Trial name
- NCT07006714
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Miami
Breast Cancer
Remotely-Delivered Cognitive Behavioral Stress Management for Breast Cancer (R-CBSM)
The purpose of this research study to find out if a program called Remotely-delivered Cognitive Behavioral Stress Management (R-CBSM) can help women with breast cancer in the period of survivorship after they have completed…
- Trial name
- NCT07502352
- Testing
- Remotely Delivered Cognitive Behavioral Stress Management Intervention (R-CBSM), Standard of Care Survivorship Care Planning
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of Miami
Multiple Myeloma
ERd Combination Treatment in Newly Diagnosed Multiple Myeloma (ADVANCE 2.0)
The purpose of this study is to determine the effects that Elranatamab in combination with Lenalidomide and Dexamethasone has on participants that have been newly diagnosed with Multiple Myeloma.
- Trial name
- NCT06997081
- Testing
- Lenalidomide, Dexamethasone, Elranatamab
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Miami
Mental Health Issue, Anxiety Disorder
Unified Protocol: Community Connections
The purpose of this study is to administer the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) and Adolescents (UP-A) to youth and participants' parents and to examine the efficacy and…
- Conditions
- Mental Health Issue, Anxiety Disorder, Depressive Disorder, Parenting
- Trial name
- NCT06038721
- Testing
- The Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Children, The Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Adolescents
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of Miami
Depression, HIV
Implementing Depression and Adherence Treatment
The goal of this clinical trial is to compare a core set and enhanced set of implementation strategies in increasing the reach of evidence-based treatments to patients with HIV and depression.
- Conditions
- Depression, HIV, Adherence, Treatment, AIDS
- Trial name
- NCT07032363
- Testing
- Core Implementation Strategies, Enhanced Implementation Strategies
- Where
- South Africa
- Volunteers
- 10 people
- Sponsor
- University of Miami
Metastatic Pancreatic Ductal Adenocarcinoma, Pancreatic Ductal Adenocarcinoma
Utility of ctDNA in Early Switch of First-line Chemotherapy in Metastatic Pancreatic Ductal Adenocarcinoma
The purpose of this study is to understand whether a blood-based test called circulating tumor DNA (ctDNA) can detect whether participants are having a desired tumor shrinkage or an undesired lack of tumor shrinkage, and to study…
- Trial name
- NCT07096362
- Testing
- 5-Fluorouracil, Oxaliplatin, Leucovorin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Marginal Zone Lymphoma
Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma
The purpose of this research study is to see if loncastuximab tesirine has any benefits at dose levels researchers found acceptable in earlier studies in patients with related forms of immune cell cancers.
- Trial name
- NCT05296070
- Testing
- Loncastuximab tesirine 150 µg/Kg, Loncastuximab tesirine 75µg/Kg
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Asthma in Children, Artificial Intelligence
Artificially Intelligent Robot Control
The purpose of the study is to compare the impact of standard asthma education with the standard + Artificially Intelligent Robot (AIR) Control intervention.
- Conditions
- Asthma in Children, Artificial Intelligence, Caregiver Burden
- Trial name
- AIR (NCT07738016)
- Testing
- Artificially Intelligent Robot (AIR) Control Intervention, Standard Asthma Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Miami
Multiple Sclerosis, Dry Eye Syndromes
Clinical Applications of Advanced Ophthalmic Imaging
The purpose of this study is to determine the clinical application of advanced ophthalmic imaging devices such as optical coherence tomography (OCT), retinal function imager (RFI), slit-lamp biomicroscopy (SLB), PERG in diseased…
- Conditions
- Multiple Sclerosis, Dry Eye Syndromes, Diabetic Retinopathy, Presbyopia
- Trial name
- NCT03135327
- Testing
- Ocufolin
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Miami
Adherence, Medication
Life-Steps Counseling to Enhance Adherence and Engagement in PrEP Care
The purpose of this study is to test how different types of interventions may affect how someone takes their pre-exposure prophylaxis (PrEP) medication.
- Trial name
- NCT04316715
- Testing
- Lifesteps for PrEP, Daily text message reminders
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Miami