Clinical trials: Phase not applicable, completed
Oxidative Stress
Turmeric Extract and Oxidative Stress in Muaythai Athletes and Sedentary Men
This study examined whether taking turmeric extract for 28 days affects oxidative stress and antioxidant defenses in healthy men who practice Muaythai and men who do not exercise regularly.
- Trial name
- NCT07904598
- Testing
- Turmeric Extract, Structured Muaythai Training
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sinan Ağlar
Dental Implant Stability
Early Loading for Implants With Calcium Titanate Surface Technology in Posterior Mandibular Bone
Dental implants have revolutionized oral rehabilitation for partially edentulous patients. Recent advances in implant design and surface treatments have prompted the investigation of early loading methods, which aim to minimize…
- Trial name
- NCT07551128
- Testing
- Early implant loading, Delayed loading
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Alexandria University
CLASS II DIVISION 1 MALOCCLUSION
Root Shortening With Three Different Methods of Upper Anterior Teeth Retraction
External apical root resorption is a possible side effect of fixed orthodontic treatment, particularly in the upper front teeth.
- Trial name
- NCT07906951
- Testing
- Bidimensional Bracket System, Hybrid Dual-Section Archwire, Conventional Sliding Mechanics
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Hiv, Alcohol Problem
Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA
This study is designed to examine the efficacy of an alcohol-focused brief intervention alone versus the brief intervention plus referral to a transdiagnostic cognitive-behavioral intervention to address unhealthy alcohol use and…
- Trial name
- TALC (NCT04955795)
- Testing
- Alcohol Brief Intervention (BI), Common Elements Treatment Approach (CETA) via Telemedicine
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- University of Alabama at Birmingham
Anxiety, Depression, Anxiety
Effectiveness of HabitWorks and Symptom Tracking for Anxiety and Depression
The objective is to conduct a randomized controlled trial (RCT) that compares two digital interventions - Symptom Tracking and the HabitWorks app - in a sample of adults endorsing symptoms of anxiety or depression.
- Trial name
- NCT07025486
- Testing
- HabitWorks, Symptom TRacking
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Mclean Hospital
Schizophrenia, Schizoaffective Disorder
Effectiveness of Motivation Skills Training (MST)
This study will take place at four outpatient clinics serving adults with serious mental illness. Informed consent will be obtained from N=80 individuals with a Diagnostic and Statistical Manual of Mental Illnesses (DSM)-5…
- Trial name
- MST (NCT05805397)
- Testing
- Motivation Skills Training, Healthy Behaviors Control Group
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Columbia University
Lumbar Degenerative Disease, Lumbar Spondylolisthesis
Perioperative Nutrition Management in Patients Undergoing Open Posterior Lumbar Surgery
Patients undergoing open posterior lumbar fusion surgery often experience postoperative gastrointestinal problems, such as bloating, constipation, and delayed passage of gas and stool, and may be at nutritional risk.
- Conditions
- Lumbar Degenerative Disease, Lumbar Spondylolisthesis, Lumbar Disc Herniation
- Trial name
- NCT07893938
- Testing
- Oral nutritional supplements (ONS), Carbohydrate loading (OCL), 'Probiotics (Bifidobacterium and Lactobacillus triple live capsules)'
- Where
- China
- Volunteers
- 90 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Malignant Pleural Mesothelioma
Hemithoracic Arc Radiotherapy Post Pleural Decortication
Malignant Pleural Mesothelioma is an aggressive and refractory disease , the most aggressive treatment plan offered to these patients include trimodalitiy approach with chemotherapy as the mainstay of treatment .
- Trial name
- NCT06910449
- Testing
- hemithoracic Volumetric Arc Radiotherapy post Pleural decortication
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Insomnia
Efficacy Assessment of Probiotics in Improving Sleep Indices
To determine whether PS150 (1) reduces insomnia symptoms, (2) improves sleep quality, (3) adjusts autonomic nervous system functioning, (4) reduces the severity of anxiety and depressive symptoms, and (5) adjusts microbiome and…
- Trial name
- NCT06361368
- Testing
- PS150
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- National Yang Ming Chiao Tung University
Advanced Care Planning (ACP), ELDERLY PEOPLE
Advance Care Planning Impact on the Consistency of Older Adults With Lung Cancer and Their Potential Surrogates Regarding Life-Sustaining Treatment Preferences
This randomized controlled trial examined whether an advance care planning (ACP) tabletop game ("Walking with Wishes") could improve the consistency of life-sustaining treatment preferences between older adults with lung cancer…
- Conditions
- Advanced Care Planning (ACP), ELDERLY PEOPLE, Lung Cancer (NSCLC)
- Trial name
- NCT06616909
- Testing
- ACP GAME, acp manual
- Where
- Taiwan
- Volunteers
- 124 people
- Sponsor
- National Taiwan University Hospital
Epidermolysis Bullosa (EB), Chronic Wounds
Topical Insulin Versus Irradiated Amniotic Fluid Gel for Wound Healing in Epidermolysis Bullosa
This study aims to evaluate and compare the safety and efficacy of topical insulin and topical irradiated amniotic fluid gel in promoting wound healing in patients with epidermolysis bullosa (EB).
- Conditions
- Epidermolysis Bullosa (EB), Chronic Wounds, Wound Healing
- Trial name
- EB-INS-AFG (NCT07907523)
- Testing
- Topical Insulin (Actrapid®), Topical Irradiated Amniotic Fluid Gel, No active study treatment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Bronchiectasis
N- Acetylcysteine in Airway Clearance in Bronchiectasis
It has been deduced that reducing the production of mucus or improving the clearance of sputum in the airway is the key to enhance the therapeutic efficacy for bronchiectasis.
- Trial name
- NCT07293884
- Testing
- N Acetyle cysteine given by IV injection, Nebulized N Acetyle cysteine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Hepatitis C,Chronic Children, Only
Twelve Weeks Sofosbuvir/Daclatasvir in HCV Infected Children Aged 6-18 Years
Recently the era of direct-acting antiviral drugs for hepatitis C treatment has changed the world map of HCV. Results in adults are promising. FDA approved only two drugs in the pediatric age group 12 to 17 years.
- Trial name
- NCT07905989
- Testing
- Sofosbuvir/Daclatasvir
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- National Liver Institute, Egypt
Healthy Eating, Nutrition Literacy
Screen-Based Simulation for Adolescents' Healthy Eating Attitudes and Nutrition Literacy
This randomized controlled trial aimed to evaluate the effect of healthy eating education delivered through screen-based simulation on healthy eating attitudes and nutrition literacy in adolescents attending a high school.
- Conditions
- Healthy Eating, Nutrition Literacy, Adolescent Nutrition
- Trial name
- NCT07901361
- Testing
- Screen-Based Simulation Healthy Eating Education, Slide Presentation Healthy Eating Education
- Where
- Turkey (Türkiye)
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Behavioral Insomnia of Childhood
Development of Sleep Intervention for Parent and Child
This study aims to develop and test the intervention program to help manage parental thoughts in parents with child sleep problems.
- Trial name
- NCT05806450
- Testing
- Intervention, Active control condition
- Where
- South Korea
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Sungshin Women's University
Pacemaker DDD, Implantable Defibrillator User
Remote Alert Pathway To Optimize CaRe of Cardiac Implantable Electrical Devices
The Remote Alert Pathway to Optimize Care of Cardiac Implantable Electrical Devices (RAPTOR-CIED) Study is a pragmatic, multi-center, randomized trial with 1:1 patient-level randomization comparing the safety and effectiveness of…
- Trial name
- RAPTOR-CIED (NCT06937658)
- Testing
- Alert-based care, Guideline-based care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Beth Israel Deaconess Medical Center
Coronary Artery Disease, Coronary Syndrome
Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With (N)STEMI or Unstable Angina
The POLARSTAR study is an early safety and feasibility study to evaluate the performance and safety of the CryoTherapy System (CTS) for the treatment of coronary plaque lesions that are not obstructing blood flow but are at…
- Conditions
- Coronary Artery Disease, Coronary Syndrome, Cryotherapy Effect, Myocardial Infarction
- Trial name
- POLARSTAR (NCT05600088)
- Testing
- CryoTherapy System (CTS)
- Where
- 5 sites in Georgia, Lithuania
- Volunteers
- 24 people
- Sponsor
- Cryotherapeutics SA
Orthodontic Tooth Movement
Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol
The hypothesis of this project is that replacing the current 7-day wear protocol with a 3-day wear protocol, while integrating less tooth movement per aligner (reduce the amount of activation per aligner) may produce more…
- Trial name
- NCT05905224
- Testing
- Invisalign 7-day wear protocol, Invisalign 3-day wear protocol
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Brain Injury, Virtual Reality
Effects of Virtual Reality With Multisensory Stimulation on Emotional and Behavioral Disorders in Individuals With Acquired Brain Injury and Disability Requiring Institutional Care: a Single Case Experimental Design (SCED) Study.
Acquired brain injuries (ABIs) frequently cause emotional and behavioral disorders that impair independence and quality of life, particularly in institutions.
- Conditions
- Brain Injury, Virtual Reality, Behavior, Emotion
- Trial name
- Rév In MAS (NCT07371260)
- Testing
- Virtual reality
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Hopital La Musse
Amputation
A Unique Body-Powered Terminal Device With Enhanced Grasping Capabilities for Individuals With Upper Limb Loss
We have developed a novel terminal device for a prosthetic arm that eliminates the functional tradeoffs seen in body-powered voluntary open devices.
- Trial name
- NCT07254247
- Testing
- Novel Prosthetic Hook, Control Hook (Light Spring), Control Hook (Heavy Spring)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Little Room Innovations, LLC
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