Clinical trials: Biochemical Marker
Heart Failure, Congenital Heart Defects
Right Ventricular Failure in Congenital Heart Defects
Usually, "heart failure" refers to myocardial insufficiency of the left ventricle. However, in patients with congenital heart defects, often predominantly the right ventricle is affected.
- Trial name
- NCT00266201
- Where
- 9 sites in Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Competence Network for Congenital Heart Defects
Inflammatory Bowel Disease, Colitis, Ulcerative
Biomarkers in Inflammatory Bowel Diseases
Ulcerative colitis (UC) and Crohn's disease (CD) are chronic relapsing inflammatory bowel diseases (IBD). At the time of diagnosis it is not possible to predict the course of the disease, which can range from a few flares in a…
- Conditions
- Inflammatory Bowel Disease, Colitis, Ulcerative, Crohn Disease
- Trial name
- NCT02612103
- Where
- Denmark
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Line Elberg Godskesen
Aging, Obesity
Resistance Exercise Training in the Older Population With Obesity
Background: Aging leads to an alteration in the immune response, characterized by a chronic inflammatory state, and a progressive decrease in muscle quantity and quality, a situation that increases in women and in the presence of…
- Trial name
- RETOPO (NCT06367296)
- Testing
- Prolonged resistance exercise training
- Where
- 2 sites in Chile
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Osteoarthritis, Articular Cartilage Disorder of Knee
Serum Cartilage Oligomeric Matrix Protein Levels After 12 Weeks of Different Exercises
Acute effects of physical exercise on the deformational behavior of articular cartilage and changes in cartilage oligomeric matrix protein (COMP) are definite.
- Conditions
- Osteoarthritis, Articular Cartilage Disorder of Knee, Degenerative Lesion of Articular Cartilage of Knee
- Trial name
- NCT01576159
- Testing
- Running exercise, Cycling exercise, Swimming Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Middle East Technical University
Metabolic Syndrome, Obesity
New Biomarkers for Predicting Systemic Complications in Obesity
This observational cross-sectional study classified participants into obesity classes (Class I: BMI 30.0-34.9, Class II: 35.0-39.9, Class III: ≥40.0 kg/m²) based on WHO criteria.
- Trial name
- NCT07260487
- Where
- Turkey (Türkiye)
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Biochemical Markers
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects
The effect of physical activity on serum cartilage biomarkers is largely unknown. This study is critical to increase our knowledge of the physiological cartilage response to activities of daily living and dynamic tasks by…
- Trial name
- NCT06757699
- Testing
- Walking, Cycling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kocaeli University
Athletic Performance, Soccer
The Effect of a Training Programme in the Variation of Fitness Parameters, Physiological, Hematological and Biochemical Indicators of Soccer Players During the Preseason Period
The goal of this study is to investigate the effects of varying friendly match-play exposure during the late pre-season on physiological, biochemical, and performance adaptations in soccer players.
- Conditions
- Athletic Performance, Soccer, Muscle Damage, Inflammation
- Trial name
- NCT07170930
- Testing
- Friendly Match-Play Exposure: extended vs. limited
- Where
- Greece
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Emmanouil D. Zacharakis
Primary Prevention
Genetical, Anthropometrical and Biochemical Factors Influencing High Risk Subclinical Atherosclerosis
Subclinical atherosclerosis is the atherosclerotic process identified before clinical symptoms and thus it can be a useful marker of future cardiovascular events. It can be evaluated by many methods.
- Trial name
- NCT02487615
- Where
- 2 sites in Brazil
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Premature Ventricular Complexes, Diet Quality
Premature Ventricular Complex and Diet Inflamatuar Index
The aim of this study is to evaluate differences in energy, macro- and micronutrient intakes, dietary characteristics, quality of life, and biochemical parameters between individuals with and without premature ventricular…
- Conditions
- Premature Ventricular Complexes, Diet Quality, Biochemical Markers, Life Quality
- Trial name
- PVT (NCT07870109)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Pregnancy, Fetal Aneuploidy
Biochemical Markers and 2 and 3D Ultrasound to ID Maternal & Fetal Complications
Can a combination of prenatal screening blood tests, early ultrasound, and a 3D ultrasound of the fetal face at approximately 20 weeks gestation identify fetuses with congenital anomalies and predict maternal and fetal…
- Trial name
- NCT01404221
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Healthy Adults
The Dose Response of Prednisone on Biochemical and Clinical Makers in Adult Healthy Volunteers
The purpose of this study is to further access the utility of biochemical and clinical biomarkers for glucocorticoid-mediated anti-inflammatory effects and safety endpoints against which dissociated agonists of the glucocorticoid…
- Trial name
- NCT02767089
- Testing
- Prednisone
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cognitive Change
Effect of Alpha Hope Dietary Supplement on Health and Cognitive Performance
The purpose of the present research study is to evaluate the claims about the supplement influencing cognitive function that may impact performance on cognitive task and related biochemical measures.
- Trial name
- NCT05589051
- Testing
- Drink
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Ozone Therapy, Muscle Damage
Effects of Ozone Therapy on Muscle Damage
The goal of this clinical trial is to determine the effectiveness of different ozone therapy methods in enhancing recovery after muscle-damaging exercise in healthy adults, and to evaluate their impact on biochemical markers of…
- Conditions
- Ozone Therapy, Muscle Damage, Oxidative Stress, Recovery
- Trial name
- NCT07728422
- Testing
- Autohemotherapy, Ozone Sauna Therapy, Ozonated Lavender Oil Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Inonu University
Hypertrophy, Physical Performance
Protein Ingestion Timing on Body Composition and Biochemical Markers in Resistance-trained Males
Protein ingestion timing is an important component for muscle accretion. The investigators hypothesized that protein ingestion timing could affect muscular adaptations and performance in resistance-trained men.
- Trial name
- NCT05544955
- Testing
- isolate whey protein prior to and immediately after resistance training, isolate whey protein 3 hours prior to and 3 hours after resistance training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marymount University
Craving, Mastication Disorder
Effects of Non-invasive Neuromodulation on Food Desire, Chewing Pattern, Executive Functions and Oxidative Stress.
From the change in self-regulation, memory is inhibited, allowing individuals to suppress or ignore unwanted or outdated associations and thus help to filter information relevant to dietary goals from irrelevant information.
- Conditions
- Craving, Mastication Disorder, Memory Disorders, Executive Dysfunction
- Trial name
- NCT05046145
- Testing
- speech therapy for chewing + real tDCS
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Piauí
Sports Nutrition, Biochemical Markers
The Effect of Colostrum Bovinum Supplementation in Endurance Athletes
The purpose of this study was to verify the effect of chronic 12-week high-dose Colostrum Bovinum (COL) and placebo (PLA) supplementation on immunological, hematological and biochemical markers, as well as physical capacity and…
- Conditions
- Sports Nutrition, Biochemical Markers, Exercise Performance, Aerobic Capacity
- Trial name
- NCT06390670
- Testing
- Colostrum Bovinum supplementation
- Where
- Poland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Healthy Volunteers
Study of Biochemical Markers to Determine the Acetylsalicylic Acid Chemopreventive Effect Through Antiplatelet Action
This study in healthy volunteers is the first step in developing a collaborative research program, which seeks to test the hypothesis that chemopreventive effect of acetylsalicylic acid (ASA) on colon cancer is due predominantly…
- Trial name
- NCT02060396
- Testing
- Acetylsalicylic acid
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aragon Institute of Health Sciences
Hypertensive Heart Disease Without (Congestive) Heart Failure
The Influence of Beetroot Powder at a Dose of 20 g on Blood Pressure, Microcirculation, and Biochemical Markers in Men With Arterial Hypertension.SVEKLA2025.
Objective: to evaluate the effectiveness of using a food product, dry finely dispersed beetroot powder in a dose of 20 g, containing 800 mg of nitrate (NO3-), in relation to the regulation of blood pressure in men with…
- Trial name
- NCT07270718
- Testing
- Plus SVEKLA
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Osteoporosis
A Study to Test Once-Weekly Doses of Odanacatib (MK0822) on Healthy Adult Females (0822-005)(COMPLETED)
This study will assess the safety, tolerability, PK, and PD of a once weekly dose of MK0822 in healthy postmenopausal women.
- Trial name
- NCT00770159
- Testing
- odanacatib
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Beta-Thalassemia
Iron Status in BTM With Blood Transfusion
To assess the possible role of iron overload as a cause of liver dysfunction in thalassemic childrens receiving multiple blood transfusion and its correlation with serum aminotransferases.
- Trial name
- NCT04947540
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University