Clinical trials: Chlorhexidine
Periodontal Disease
Evaluation and Comparison of the Efficacy of Triphala Mouthwash and 0.2% Chlorhexidine
The purpose of this study is to evaluate the usefulness of triphala mouthwash in comparison with the gold standard chlorhexidine in hospitalized and periodontally diseased patients.
- Trial name
- NCT01900535
- Volunteers
- 120 people
- Sponsor
- Tatyasaheb Kore Dental College
Alveolar Osteitis
Efficacy of 0.2 % Digluconate Chlorhexidine Mouthwash for Preventing Alveolar Osteitis After Third Molar Extraction
The purpose of this study is to demonstrate the efficacy of 0.2 % digluconate chlorhexidine mouthwash in the prevention of alveolar osteitis following third molar extraction and to evaluate the safety and local tolerability.
- Trial name
- NCT02382809
- Testing
- DC071
- Where
- 18 sites in Estonia, France and 2 more
- Volunteers
- 414 people
- Sponsor
- Pierre Fabre Medicament
Sepsis Affecting Skin, Central Venous Catheter Related Bacteremia
Comparison Trial for Chloraprep Versus Aqueous Chlorhexidine (2%) for the Prevention of Catheter-related Bacteremia
A multicentre, open-label clinical trial of two groups comparing cutaneous asepsis with chlorhexidine gluconate at 2% + isopropyl alcohol 70% in relation to the placement of central venous catheters (Study group) with standard…
- Trial name
- NCT03489512
- Testing
- A (Chloraprep), B (Clorhexidine 2%)
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Class II Dental Caries
Clinical Performance of Bulk-Fill Composite Using With Adhesives With or Without Chlorhexidine
This study aims to evaluate the clinical success of chlorhexidine-containing dentin bonding agent in primary molars with a 12-month follow-up.
- Trial name
- NCT06257108
- Testing
- Class II Cavity Restorations
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uşak University
Stage II Grade B Periodontitis
Clinical & Biochemical Evaluation of Antioxidant Vs. Chlorhexidine as an Adjunctive to Non-Surgical Treatment of Stage II-grade B Periodontitis
This randomized clinical trial aims to evaluate and compare the clinical and biochemical effects of an antioxidant agent and chlorhexidine when used as adjuncts to non-surgical periodontal therapy in patients with Stage II Grade…
- Trial name
- NCT07801417
- Testing
- Perioscience Gel, High Cure Chlorhexidine Gel, High Cure Chlorhexidine Gel + Perioscience Gel
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Al-Azhar University
Healthcare Associated Infection, Nosocomial Infection
Red Light Photobiomodulation and Topical Disinfectants
The goal of this clinical trial is to evaluate the potential effects of photobiomodulation when used with topical disinfectants in the anterior nares of healthy adults.
- Conditions
- Healthcare Associated Infection, Nosocomial Infection, Surgical Site Infection
- Trial name
- NCT05797818
- Testing
- Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ondine Biomedical Inc.
Reducing Gingivitis, Clinical Effect
Effectiveness of Coconut Oil Pulling and Moringa Mouthwash Versus Chlorhexidine in Reducing Gingivitis in Diabetic Children
Gingivitis is a common and reversible inflammatory condition, mainly caused by dental plaque, and is particularly prevalent among children.
- Trial name
- NCT07826390
- Testing
- Chlorhexidine mouthwash, Moringa olfera mouthwash, coconut oil pulling
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Amira Yehia Zakaria
Stem Cell Transplant Complications, Oral Mucositis
Compound Staphylococcal Lysostaphin Vs. Chlorhexidine Mouthrinse for Oral Mucositis in Patients Undergoing Allo-HSCT
Oral mucositis (OM) is a common complication in patients receiving myeloablative conditioning allogeneic hematopoietic stem cell transplantation (allo-HSCT).
- Trial name
- NCT06791746
- Testing
- compound Staphylococcal lysostaphin mouthrinse, chlorhexidine mouthrinse
- Where
- China
- Volunteers
- 388 people
- Sponsor
- Zhejiang University
Periapical Diseases
Effect of QMix 2in1 as Final Irrigation Protocol on Periapical Healing
Aim: To compare the 12-month radiographic outcome of root canal treatment with and without the additional use of QMix 2-in-1 (Dentsply Tulsa, Maillefer, Ballaigues, Switzerland) irrigation solution.
- Trial name
- NCT04348578
- Testing
- QMix 2in1
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Gingivitis, Periodontitis
A Clinical Trial to Study the Effects of Two Home Made Mouthwashes in Patients With Gum Diseases
Periodontal Disease is a ubiquitous in nature affecting about 80% population of India. The Periodontal Disease is a multifactorial but the dental plaque is considered as main etiological agent.The dental plaque, a adhesive…
- Trial name
- NCT02546804
- Testing
- HOT SALT WATER, POTASSIUM PERMANGANATE, CHLORHEXIDINE
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government College of Dentistry, Indore
Dental Plaque
Efficacy of Two Commercially Available Chlorhexidine Mouthrinses Non-alcohol Base
The purpose of this study was to compare the antiplaque efficacy of a 0,12% chlorhexidine and 0,05% cetyl-pyridinium chloride mouth rinse (Perio-aid®) with a 0,2% chlorhexidine non-alcohol base mouth rinse (Corsodyl Care®).
- Trial name
- NCT01580943
- Testing
- Chlorhexidine
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Peritoneal Dialysis Catheter Exit Site Infection, End Stage Renal Disease on Dialysis
Chlorhexidine Gluconate-gel Dressing for Exit Site Infection in Peritoneal Dialysis
Exit site infection (ESI) is one of the major predisposing factors to peritoneal dialysis (PD) related peritonitis. Chlorhexidine Gluconate (CHG) has been widely used for cutaneous disinfection for half a century.
- Conditions
- Peritoneal Dialysis Catheter Exit Site Infection, End Stage Renal Disease on Dialysis, Dialysis; Complications
- Trial name
- NCT06022835
- Testing
- Chlorhexidine Gluconate-gel (CHG) Dressing
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- National Healthcare Group, Singapore
Unrecognized Condition
Effect of TCFA on Neointimal Coverage After PCI at 9 Months Follow-up
Although drug-eluting stents have reduced rates of restenosis and late lumen loss compared with bare metal stents, late stent thrombosis (LST), a life-threatening complication of this technology, has emerged as a major concern.
- Trial name
- NCT02384837
- Testing
- EXCEL biodegradable polymer-coated sirolimus-eluting stent
- Where
- China
- Volunteers
- 33 people
- Sponsor
- General Hospital of Chinese Armed Police Forces
C. Acnes, Arthroscopic Rotator Cuff Repair
Can Additional Preoperative Skin Cleaning on Face, Neck and Chest With Chlorhexidine Reduce Cutibacterium Acnes Contamination on Sutures in Arthroscopy Rotator Cuff Repair?
The purpose of our study was to investigate whether preoperative skin cleaning on face, neck, and chest with chlorhexidine could reduce suture contamination of C. acnes in arthroscopic rotator cuff repair.
- Trial name
- NCT04483063
- Testing
- 2% chlorhexidine gluconate skin cleanser
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Cheng-Kung University Hospital
Hysterectomy
Vaginal Preparation Prior to Hysterectomy
This is a randomized controlled trial to determine the influence of chlorhexidine gluconate surgical/topical antiseptic solutions on the bacterial environment of the vagina during hysterectomy and compare that to the effect of…
- Trial name
- NCT03412734
- Testing
- Chlorhexidine, Iodine
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- TriHealth Inc.
Infection
Prevention of Catheter-Related Bloodstream Infection in Patients With Hemato-Oncological Disease
The aim of this prospective randomised controlled trial is to compare the incidence of catheter-related bloodstream infection in 2 groups of patients with hemato-oncological disease: Group A: heparin-coated central venous…
- Trial name
- NCT00413738
- Testing
- Antiseptic-coated central venous catheters
- Sponsor
- Centre National de Greffe de Moelle Osseuse
Oral Ulcer
Aloe Vera and Chlorhexidine Against Traumatic Oral Ulcers
The development of gingivitis in patients during orthodontic treatment is widely known, with the characteristic response of gingival inflammation and hyperplasia and traumatic rashes or ulcerations of the oral mucosa derived from…
- Trial name
- NCT03633292
- Testing
- Antiseptic clorhexidine gel (Lacer, Barcelona, Spain), Master formula of aloe vera gel 80%
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Orthodontic Appliance Complication, Dental Caries
Effect of Chlorhexidine Gel on Bacterial Count During Fixed Orthodontic Treatment
This study investigates the benefit of using chlorhexidine gel as an antimicrobial agent in orthodontic patient to reduce caries risk and the possible consequential effect of this use on the orthodontic brackets used for the…
- Trial name
- NCT02001311
- Testing
- Chlorhexidine gluconate
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Ventilator Associated Pneumonia
Chlorhexidine Gluconate Oral Care for Adults Experiencing Trauma
Examine the use of 0.12% Chlorhexidine Gluconate as an adjunct to current oral care protocol for trauma patients on ventilator support to decrease the incidence of Ventilator Associated Pneumonia and oral bacterial load.
- Trial name
- NCT01382446
- Testing
- Chlorhexidine gluconate, Toothpaste
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Neutropenia
Mouthwash With Chlorhexidine 0.12%/Ethyl Alcohol 7% Compared to Ethyl Alcohol 7%
Clinical triple-blind randomized controlled trial to assess the use of two different mouthwashes to reduce the oral colonization by gramnegative bacteria in patients with chemotherapy
- Trial name
- NCT02414581
- Testing
- chlorhexidine 0.12%/Ethyl alcohol 7%, Ethyl Alcohol 7%, Chlorhexidine 2%/Ethyl alcohol 7%
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio