Clinical trials: Colonoscopy Procedure
Colorectal Cancer
e-Motivación: Developing and Pilot Testing an App to Improve Latinos' Screening Colonoscopy Rates
Among Latinos, a fast growing and underserved population, Colorectal Cancer (CRC) is the third leading cause of cancer death in men and in women.
- Trial name
- NCT04987788
- Testing
- Motívate, Video link
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colonoscopy
Effectiveness of Stiffening Wire in Colonoscopy With Pre-Owned Colonoscopes
The study aims to determine whether a proprietary, FDA approved stiffening wire improves the efficiency of colonoscopy (that is, decreases the duration of the procedure) and/or enables complete visualization of the colon in a…
- Trial name
- NCT01115010
- Testing
- Colonoscope stiffening device
- Where
- Jamaica
- Volunteers
- 112 people
- Sponsor
- Cornwall Regional Hospital
Adenoma, Polyps
Prospective Trial to Compare ADR of G-EYE™ Colonoscopy With Standard Colonoscopy
The purpose of this study is to compare the adenoma detection rate (ADR) of the G-EYE™ colonoscopy with that of standard colonoscopy.
- Conditions
- Adenoma, Polyps, Colorectal Cancer
- Trial name
- NCT02545699
- Testing
- G-EYE™ Colonoscopy, Standard Colonoscopy
- Where
- Israel
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colonoscopy
A Phase III Trial to Assess the Efficacy, Acceptability and Safety of Moviprep® Versus a 4L PEG+E Standard Solution
The study was carried out as a randomised, single-blind, active-controlled, multi-centric, phase III study with two parallel treatment groups.
- Trial name
- NCT00389233
- Testing
- Macrogol3350 NA sulphate NACl KCl ascorbic acid NA ascorbate, Macrogol3350 Na sulphate Na bicarbonate NaCl KCl
- Where
- 12 sites in Germany
- Volunteers
- 360 people
- Sponsor
- Norgine
Sedation Problems, Breathing Complications
Patient Positioning During Colonoscopy: Effects on Safety and Diagnostic Outcome
The purpose of this study is to determine the effects of patient positioning during colonoscopy on patient safety and diagnostic outcome.
- Trial name
- PACSO (NCT02001792)
- Testing
- Position the patient during colonoscopy, pulse oximeter
- Where
- 2 sites in Germany
- Volunteers
- 412 people
- Sponsor
- Technical University of Munich
Colorectal Cancer
Interventions to Improve Colon Cancer Screening in Poor Rural Iowa Counties
The goal of the study is to conduct a randomized clinical trial to test several office-based strategies for improving colon cancer screening among individuals who are regular patients at 16 family practice physician offices in…
- Trial name
- NCT01477814
- Testing
- Physician chart reminder, chart reminder, educational mat'ls, FIT, CR,ed mat'ls, FIT, phone call
- Where
- United States
- Volunteers
- 743 people, healthy volunteers welcome
- Sponsor
- Barcey T. Levy
Colonoscopy
Study 301: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
The purpose of this study is to compare the safety and efficacy of BLI4900 bowel preparation to an FDA-approved control as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT04446299
- Testing
- Bowel Prep
- Where
- 25 sites in United States
- Volunteers
- 519 people
- Sponsor
- Braintree Laboratories
Colon Polyp
Water-only Versus Water-CO2 (Hybrid) Colonoscopy Insertion Technique
The colonoscopy procedure involves insertion of a thin, flexible tube with a tiny camera inside (colonoscope) passed inside the bowel.
- Trial name
- WAVE (NCT04710706)
- Testing
- Colonoscopy insertion technique used during procedure
- Where
- United Kingdom
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Crohn's Disease, Recurrence
Crohn's Extent of Resection Trial
The trial will investigate if removing an additional length of small bowel will result in lower risk of recurrence at the surgical join (anastomosis), thereby decreasing the need for further surgery in the future.
- Trial name
- CERT (NCT01876264)
- Testing
- Extended resection, Conventional resection
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust
Inflammatory Bowel Diseases, Microbiota
Evaluation of the Diagnostic Potential of Artificial Intelligence-assisted Fecal Microbiome Testing for Inflammatory Bowel Disease
The goal of this clinical trial is to evaluate the diagnostic potential of Artificial Intelligence-assisted Fecal Microbiome Testing for the diagnosis of inflammatory bowel disease.
- Conditions
- Inflammatory Bowel Diseases, Microbiota, Colonoscopy
- Trial name
- NCT05797207
- Testing
- Artificial Intelligence-assisted Fecal Microbiome Testing, Colonoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Istanbul Medipol University Hospital
Serrated Polyp
Serrated Polyp Detection Rate Between Carbon Dioxide and Air Insufflation
Sessile serrated adenomas are characterized by their flat shape and the presence of a yellow mucus cap overlying the lesion. These morphological features may account for their diagnostic difficulty during colonoscopy.
- Trial name
- NCT03623906
- Testing
- Carbon dioxide insufflation colonoscopy, Air insufflation colonoscopy
- Volunteers
- 1,280 people
- Sponsor
- The Catholic University of Korea
Colorectal Neoplasms Malignant, Colonoscopy
Sensitivity of Fecal Immunochemical Test (FIT) for Colorectal Cancer (CRC) Screening
Fecal immunochemical test (FIT) was introduced in France late 2015, FIT has better diagnostic accuracy for colorectal cancers (CRCs) than previous screening tests.
- Conditions
- Colorectal Neoplasms Malignant, Colonoscopy, Early Detection of Cancer, Female
- Trial name
- FITBACK (NCT05163236)
- Testing
- Positive fecal immunochemical test (FIT), Negative fecal immunochemical test (FIT), Fecal immunochemical test (FIT) not performed
- Where
- France
- Volunteers
- 1,149 people
- Sponsor
- University Hospital, Brest
Colorectal Neoplasm, Colonic Polyps
Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
The investigators hypothesize that high definition colonoscopy with close focus narrow band imaging features has a high diagnostic accuracy for colorectal polyp histology, and can replace formal pathologic assessment in cases of…
- Trial name
- VALID (NCT01288833)
- Testing
- Close focus HD NBI Colonoscopy System
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Colonoscopy, Bowel Preparation Solutions
Electrolyte Beverage Combined With Polyethylene Glycol for Colonoscopy Bowel Preparation
This randomized controlled trial aims to evaluate the effects of different ratios of electrolyte beverage and water combined with polyethylene glycol (PEG) on bowel preparation quality before colonoscopy.
- Conditions
- Colonoscopy, Bowel Preparation Solutions, Colorectal Cancer Screening
- Trial name
- NCT07608120
- Testing
- PEG With Water, PEG With Low-dose Electrolyte Beverage, PEG With Medium-dose Electrolyte Beverage
- Where
- China
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Colonic Diseases
Deep Learning Algorithm for Recognition of Colonic Segments.
The purpose of this study is to develop and validate a deep learning algorithm to realize automatic recognition of colonic segments under conventional colonoscopy.
- Trial name
- NCT04087824
- Testing
- AI assisted recognition of colonic segments
- Volunteers
- 60 people
- Sponsor
- Shandong University
Colonoscopy
The Comparative Study Between Bowel Preparation Method
The purpose of this study is to compare the efficacy, acceptability and preparation-induced mucosal inflammation of PEG + ascorbic acid vs. PEG for colonoscopy.
- Trial name
- CSBPM (NCT01964417)
- Testing
- Colonoscopy after bowel cleansing
- Where
- South Korea
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Inje University
Polyp, Colorectal
Tranexamic Acid to Prevent Bleeding After Endoscopic Resection of Large Colorectal Polyps: A Pilot Project
Colorectal cancer is the second most common cancer in Canada. Colonoscopy and removal of precancerous polyps (polypectomy) reduces the incidence and mortality associated with colorectal cancer.
- Trial name
- NCT04559880
- Testing
- Tranexamic Acid Injection [Cyklokapron]
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Lawrence Charles Hookey
Colonic Adenoma, Colonoscopy
Blue Laser Imaging and White Light Imaging Colonic Polyps
The adenoma detection rate by colonoscopy for asymptomatic individuals aged 50 years and older is estimated to be at least 25%. It is known that during colonoscopy, lesions may be missed.
- Trial name
- NCT03421600
- Testing
- blue laser imaging, White light imaging
- Where
- Singapore
- Volunteers
- 184 people
- Sponsor
- Changi General Hospital
Polyposis
Endocuff for Surveillance of Serrated Polyposis Syndrome
Serrated Polyposis Syndrome (SPS) is a high-risk condition for colorectal cancer (CRC). SPS patients have a cumulative CRC risk of 1.9% in 5 years despite a strict endoscopic surveillance in specialized centers.
- Trial name
- NCT02592603
- Testing
- Endocuff-assisted Colonoscopy
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- Hospital Clinic of Barcelona
Colonic Neoplasms, Colonic Adenocarcinoma
Assessing the Additional Neoplasia Yield of Computer-aided Colonoscopy in a Screening Setting
Even if colonoscopy is considered the reference standard for the detection of colonic neoplasia, polyps are still missed. The risk of early post-colonoscopy cancer appeared to be independently predicted by a relatively low…
- Conditions
- Colonic Neoplasms, Colonic Adenocarcinoma, Polyps of Colon, Rectal Neoplasms
- Trial name
- GENIAL-CO (NCT04441580)
- Testing
- CADe colonoscopy using GI Genius device
- Where
- Italy
- Volunteers
- 900 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
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