Clinical trials: Injuries
Shoulder Injury Related to Vaccine Administration, Erosion, Localized
Ultrasound and Immunological Findings in Patients With Shoulder Injury Related to Vaccine Administration (SIRVA)
Accidental vaccine injection into adjunct shoulder structures can cause tissue damage, termed Shoulder injury related to vaccine administration (SIRVA). The immunopathological mechanisms and consequences of SIRVA are unknown.
- Trial name
- SIRVA (NCT04236193)
- Testing
- Ultrasound Shoulder and Immunological Phenotyping by FACS
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Firearm Injury
TRUsted rEsidents and Housing Assistance to Decrease Violence Exposure in New Haven
The overall objective of this study is to implement and test a strengths-based, community-driven intervention to reduce gun violence by (1) improving housing stability through providing financial assistance coupled with…
- Trial name
- TRUE HAVEN (NCT05723614)
- Testing
- TRUE HAVEN
- Where
- 7 sites in United States
- Volunteers
- 61,770 people, healthy volunteers welcome
- Sponsor
- Yale University
PTSD, Sleep Disorders
Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD
Background: Posttraumatic stress disorder (PTSD) is a debilitating and disabling mental disorder that afflicts at least 25% of Veterans who have suffered life-threatening war zone trauma.
- Trial name
- PACT (NCT00532493)
- Testing
- prazosin
- Where
- 15 sites in United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Radiation Induced Lung Injury, Non Small Cell Lung Cancer
Hyperpolarized Noble Gas MRI Detection of Radiation-Induced Lung Injury
Lung cancer is the leading cause of cancer death in the world; each year lung cancer claims over 20 000 lives in Canada and more than one million lives globally (1).
- Trial name
- NCT03632369
- Testing
- Hyperpolarized xenon-129 MRI
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thunder Bay Regional Health Research Institute
Articular Cartilage Degeneration
MechSens - Dose-response Relationship of in Vivo Ambulatory Load and Mechanosensitive Cartilage Biomarkers
This study is to investigate the effects of age, tissue status and the presence of inflammation on the in vivo dose-response relationship of ambulatory load and mechanosensitive blood markers of articular cartilage.
- Trial name
- MechSens (NCT04128566)
- Testing
- walking stress test
- Where
- Switzerland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Carpal Tunnel Syndrome
Vitamin B12 for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT03802422
- Testing
- Vitamin B12, Normal saline
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Wound Healing, Palatal Wound
The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.
The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel.
- Conditions
- Wound Healing, Palatal Wound, Donor Site Complication, Inflammatory Cytokines
- Trial name
- NCT07330154
- Testing
- Application of NBF gel after soft tissue graft surgery
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Osteoporosis, Vertebral Fracture
Evaluation of the Impact of a Case-finding Strategy for Vertebral Fractures
Postmenopausal women with vertebral fractures (VFs) represent an important target for secondary fracture prevention, but few of these patients come for clinical attention.
- Trial name
- COSHIBA (NCT00463905)
- Testing
- Clinical assessment +/- radiography
- Where
- United Kingdom
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Stress Disorders, Post-Traumatic
Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
The purpose of this study is to find out why patients with post-traumatic stress disorder (PTSD) have an increased risk for heart disease and high blood pressure later in life.
- Trial name
- ANG-P (NCT02560805)
- Testing
- Microneurography, Combat virtual reality video clip, Handgrip Exercise
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Emory University
Pain Response, Stress, Trauma
Characterizing Subjective and Physiological Responses to Stress and Pain and Cognitive Learning and Executive Function
The study design is to assess the between groups factor (controls, chronic pain, addicted individuals) and repeated measures factor of pain/stress (pain vs no pain) along with a longitudinal component to assess stress, pain and…
- Trial name
- NCT04419831
- Testing
- Yale Stress Pain Test (YSPT)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Yale University
Skin Barrier Function, Wound Healing
Clinical Observational Study on Changes in Skin Physiological Parameters Following Ablative and Non-Ablative Fractional Laser Treatment at Different Doses
This clinical observational study investigates the dose-response relationship between laser energy intensity and skin damage/repair by applying different parameter sets of fractional ablative (CO2) and non-ablative (M22) lasers…
- Trial name
- NCT07561242
- Testing
- Ablative Fractional Carbon Dioxide Laser, Non-ablative Fractional Laser (1565 nm)
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Hypoxemia, Trauma
Comparison of Pharyngeal Oxygen Delivery by Different Oxygen Masks
The intent of this study is to determine the difference in pharyngeal oxygen concentration in patients who have a natural airway (not intubated) using commonly available oxygen delivery systems.
- Conditions
- Hypoxemia, Trauma, Acute Myocardial Infarction
- Trial name
- NCT02523586
- Testing
- Oxygen administration
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Post Traumatic Stress Disorder, Trauma, Psychological
Women's Responses to a Mindfulness-Based Body Scan: A Pilot Study
PTSD develops after trauma and is marked by intrusive memories, avoidance of reminders, negative changes in mood and cognitive processes, and dysregulated physical and emotional stress reactivity.
- Trial name
- NCT05137769
- Testing
- Body Scan
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Obesity, Childhood, Risk Factor, Cardiovascular
The Svendborg-project
The main aim of this study is to describe differences in development of health and motor performance over time in relation to type of school and other background variables.
- Conditions
- Obesity, Childhood, Risk Factor, Cardiovascular, Sports Injury, Physical Activity
- Trial name
- CHAMPS-DK (NCT03510494)
- Testing
- Augmented physical education program
- Where
- Denmark
- Volunteers
- 1,209 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Neuropathic Pain, PTSD
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
This study is aimed to evaluate outpatient ketamine infusion within a military chronic neuropathic pain population and its effect on PTSD. Currently, this is a pilot study with 30 participants.
- Trial name
- NCT06414356
- Testing
- Ketamine, Magnesium sulfate, Ketamine + Magnesium sulfate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Margaux M. Salas, PhD
Achilles Tendinopathy, Flatfoot
Orthotics and Achilles Load in Runners
Compare Customized arch support orthoses (CASO) and orthotic heel lift (HL) on the effect of ATL in recreational runners with pronated feet.
- Conditions
- Achilles Tendinopathy, Flatfoot, Sports Injury
- Trial name
- NCT04003870
- Testing
- CASO, HL
- Where
- Hong Kong
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- North District Hospital
Low Birth Weight Baby, Small for Gestational Age (SGA)
Biological Impacts of Rising Temperatures on Maternal, Fetal, and Newborn Health: A Cohort Study (BIRTH Cohort)
The goal of this study is to learn how being exposed to high environmental temperatures during pregnancy affects the health of pregnant women and their babies.
- Conditions
- Low Birth Weight Baby, Small for Gestational Age (SGA), Preterm Birth, Pregnancy Complications
- Trial name
- BIRTH (NCT06957769)
- Testing
- heat stress
- Where
- 3 sites in Pakistan
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Long-Term Eccentric, Concentric & Combined Hamstring Training Improves Strength, May Cut Injury Risk, and Enhances Performance in Elite Male Football Players
Preventing Non-Contact Hamstring Injuries in Elite Footballers: Eccentric vs Concentric Training
Football is a sport with a high risk of injury, and hamstring muscle injuries are among the most common problems faced by players.
- Trial name
- NCT07395583
- Testing
- Eccentric training + regular football practice, Concentric training + regular football practice
- Where
- United Arab Emirates
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Emirates Health Services (EHS)
Sport Related Concussion
Pilot Study on the Correlation Between Accelerations Experienced
Concussion, or mild traumatic brain injury, accounts for 85% of brain injuries and is common in both professional and amateur sports.
- Trial name
- BIOIMPACT (NCT07507253)
- Testing
- Analyze correlations between the measurements of the variations in biomarkers with those obtained by an instrumented mouthguard measuring accelerations.
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Sys2Diag
Extremity Injury
Management of Chronic Pain in Military Patients With Injuries Sustained During Active Duty
The purpose of this study is to determine the degree to which spinal cord stimulation added to comprehensive medical management can provide increased relief of chronic pain in patients with injuries sustained while on active…
- Trial name
- War Wounded (NCT01616342)
- Testing
- Spinal cord stimulator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sceptor Pain Foundation
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