Clinical trials: Interventional
E-cigarette Use, Vaping
Vaper to Vaper: A Multimodal Mobile Peer Driven Intervention to Support Adolescents in Quitting Vaping
The dramatic increase in the use of e-cigarettes among U.S. adolescents has been called a national epidemic, with more adolescents now using e-cigarettes than traditional cigarettes.
- Trial name
- V2V (NCT05140915)
- Testing
- Peer Messaging, Peer Coaching via Text, Gamification
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Loneliness, Older Adults
Dynamic Neural Systems Underlying Social-emotional Functions in Older Adults
Assess the impact of a remote, app-delivered digital meditation intervention on emotional well-being of lonely older adults. Neuroimaging, electrophysiological (EEG), and autonomic physiology will be used to assess the neural…
- Conditions
- Loneliness, Older Adults, fMRI, Emotions
- Trial name
- Dynamo (NCT05645835)
- Testing
- intervention, waitlist control, No Interventions
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cognition Disorders
Impact of Glasses for Vision Problems on Cognitive Function in Rural Older Adults
The aim of this project is to explore whether vision correction can effectively slow cognitive decline in older adults. The primary question it seeks to answer is: Can providing free near and/or distance vision correction glasses…
- Trial name
- CLEVER (NCT06836440)
- Testing
- Free Prescription Glasses
- Where
- China
- Volunteers
- 964 people, healthy volunteers welcome
- Sponsor
- Yuju Wu
Metabolic Syndrome
The Pick Two to Stick To Habit Development Intervention
Metabolic syndrome (MetS) is a leading risk factor for chronic disease among African American/Black populations. Fostering habit development offers a promising new approach to improving the effectiveness of lifestyle programs for…
- Trial name
- P2S2 (NCT03370419)
- Testing
- Treatment, Usual care
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Sleep, Stress
Project MiCRIM- Sleep and Stress Intervention
The purpose of Project MiCRIM is to test the feasibility and effectiveness of an online 4-week mindfulness-based intervention that incorporates informational elements about sleep, mindfulness, thoughts, emotions, and acceptance…
- Trial name
- NCT05384067
- Testing
- Mindfulness-based intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Florida State University
Periodontitis
Impact of Supracrestal Tissue Attachment Dimension on Outcome of Scaling and Root Planing and Open Flap Debridement Procedure in Different Periodontal Phenotypes
The existence of supracrestal tissue attachment (SCTA) is fundamental for adhesion of the junctional epithelium and insertion of the connective fibers to the dental structure, besides functioning as a barrier against microbial…
- Trial name
- NCT05696600
- Testing
- Scaling and root planing and open flap debridement
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Healthy
Tuning in to Kids in School - Competence Building and Collaboration in the Team Around Primary School Students
The current project is a randomized controlled trial of the Australian evidence-based parenting program Tuning in to Kids® which has been adapted for using with Norwegian elementary school teachers (Tuning in to Kids in Schools…
- Trial name
- TIKiS (NCT06501300)
- Testing
- Emotion-focused: Tuning in to Kids in School
- Where
- Norway
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sophie Havighurst
Depression, Post Traumatic Stress Disorder
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry
While effective interventions for depression exist, their success rates are unsatisfactory and their provision is haphazard. The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Depression Hub will improve…
- Conditions
- Depression, Post Traumatic Stress Disorder, Bipolar Disorder, Mood Disorder
- Trial name
- NCT02443636
- Where
- Canada
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Gynecologic Surgical Procedures, Enhanced Recovery After Surgery
Prehabilitation Plus ERAS vs ERAS in Gynecological Surgery
Prospective, interventionist, controlled and randomized study to test the effectiveness of multimodal prehabilitation protocol in patients who will undergo gynecological surgery.
- Trial name
- NCT04505111
- Testing
- Prehabilitation Program + Enhanced Recovery After Surgery, Enhanced Recovery After Surgery
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Brasileiro de Controle do Cancer
Allogeneic Hematopoietic Stem Cell Transplantation (HSCT), Oxygen Deficiency
Impact of Closed PBSC Collection With Reduced Gas-Phase Oxygen Exposure on Graft Quality and Early Engraftment in Allo-HSCT
This study aims to establish a closed PBSC collection procedure with reduced gas-phase oxygen exposure and to verify its impact on graft functional quality and clinical engraftment efficiency.
- Conditions
- Allogeneic Hematopoietic Stem Cell Transplantation (HSCT), Oxygen Deficiency, Graft Function
- Trial name
- NCT07904234
- Testing
- Closed PBSC collection with reduced gas-phase oxygen exposure
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Obesity
Mechanical Ventilation of Obese Patients During Oral Surgical Procedures
The prevalence of obese patients in a great number of patients scheduled for elective surgery under general anesthesia has been on the increase.
- Trial name
- NCT03144609
- Testing
- low PEEP, ARM, high PEEP
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Klarić, Vlasta, M.D.
Inappropriate Prescribing, Primary Health Care
Deprescribing in Primary Health Care
Medications can help older adults but can also harm them. Frail older adults tend to have many health problems that require treatment, but are also at risk of harm from the medications prescribed.
- Conditions
- Inappropriate Prescribing, Primary Health Care, Polypharmacy
- Trial name
- NCT03903484
- Testing
- Deprescribing toolbox and intervention
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Well-Being, Psychological, Loneliness
Physiological, Hormonal, and DNA-based Mechanisms of Psychosocial Stress and Therapeutic Effect
The goal of this trial is to learn if the Groups 4 Health (G4H) intervention is effective in supporting student well-being at the University of Helsinki.
- Trial name
- NCT07152652
- Testing
- Groups 4 health
- Where
- Finland
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Preoperative Anxiety, Emergence Delirium in Pediatric Anesthesia
Ride-On Toy Car Use During Operating Room Transfer in Preschool Children
The goal of this clinical trial is to determine whether the method of transfer to the operating room can reduce preoperative anxiety and postoperative emergence delirium in male children aged 3 to 7 years undergoing elective…
- Trial name
- NCT07403747
- Testing
- Toy car, Standard Transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Sex, Unsafe, Drug Use
Addressing Substance Use Through CVCT
The proposed study developed and tested two adjunct components for use in Couples HIV Testing and Counseling (CHTC) with gay-male couples: a communication skills training video and a substance use agreement module.
- Trial name
- NCT03125915
- Testing
- Communication skills training video, substance use module, Couples HIV Testing and Counseling
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Hearing Loss
Randomised Study of Web-Based Auditory Training With Varying Perceptual and Cognitive Demands on Training Gains and Generalised Speech, Cognitive, and Communication Outcomes
WP1: PLUS-Auditory Training The goal of this experimental study is to better understand how task difficulty affects on-task learning thresholds and generalised benefits in two PLUS auditory training tasks involving perceptual and…
- Trial name
- PLUS-Optimal (NCT07506408)
- Testing
- Practice Listening and Understand Speech (PLUS)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Sleep, Physical Activity
Effects of a Wearable Device and Social Media-Based Intervention on Physical Activity and Sleep Quality in Adults
The goal of this randomized controlled trial is to examine whether the use of a wearable device and social media based intention increases physical activity and enhance sleep quality among adults.
- Trial name
- NCT06739876
- Testing
- Wearable device-based intervention (with motivational support via social media), Wearable device-based intervention (without support)
- Where
- Taiwan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Chung Hsing University
Hallux Valgus, Bunion
Early Weight-Bearing After the Lapiplasty Mini-Incision Procedure (Mini3D)
Prospective, multicenter, unblinded study to evaluate outcomes of the Lapiplasty® Procedure using the Lapiplasty® Mini-Incision™ System for patients in need of hallux valgus surgery.
- Trial name
- Mini3D (NCT05082012)
- Testing
- Treatment of Hallux Valgus
- Where
- 10 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Treace Medical Concepts, Inc.
Cognitive Function
LCoMotion. Learning, Cognition and Motion. Effect of a Four Month School-based Cluster-randomized Intervention
The purpose of this study is to determine the effect of a four months school-based physical activity intervention on cognition, academic achievement, physical activity and aerobic fitness in 12-15 year old adolescents.
- Trial name
- LCoMotion (NCT02012881)
- Testing
- Physical activity intervention, Usual practice
- Where
- Denmark
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Healthy
A Pilot Study Investigating the Effects of a Yoga Intervention on Health and Well-Being Among a Diverse Sample of Adults
The goal of this pilot study is to examine how to design a large-scale randomized control trial examining yoga as a way to improve positive body image in men and women across the lifespan.
- Trial name
- NCT05899881
- Testing
- Yoga intervention
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Brock University
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