Clinical trials: Oncological Patients
Cancer, Rectum
Converted Laparoscopic Resection of Upper Rectal Carcinoma T1-4 N0-1 in Obese Patients.
Background: laparoscopic resection (LAR) is a safe approach and widely used for rectal cancer after neoadjuvant chemo-radiotherapy, but short term and oncological outcome for converted cases to open surgery (cLAR), may be…
- Trial name
- NCT04401787
- Testing
- Anterior resection for upper rectal cancer in obese
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Patient Empowerment
Patient Education to Promote Self-management in Pain Therapy
Monocentric, uncontrolled before / after study to evaluate the effectiveness of a patient education for oncological patients by nursing staff to promote self-management in pain therapy.
- Trial name
- NCT04778384
- Testing
- Micro-training to promote self-management in pain therapy
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Luzerner Kantonsspital
Breast Cancer Female, Breast Cancer
Assessment of Oncological Safety, Quality of Life, and Environmental Impact of the Green Breast Surgery Protocol
Breast Cancer (BC) is the primary oncological diagnosis in women, with the annual incidence expected to exceed 3 million new cases by 2040 due to population growth and aging.
- Conditions
- Breast Cancer Female, Breast Cancer, Breast Neoplasms
- Trial name
- BuGs (NCT06624917)
- Testing
- Green Breast Surgery Protocol
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- University of Rome Tor Vergata
Cervical Cancer
Surgical Staging in Cervical Cancer Prior to Chemoradiation
The aim of this study is to determine whether the modified therapy on the basis of operative staging and systematic, pelvine and paraaortal lymphadenectomy for patients with cervical cancer of the FIGO stages IIB-IV prior to…
- Trial name
- uterus11 (NCT01049100)
- Testing
- lymphadenectomy, Standard Staging
- Where
- 2 sites in Germany
- Volunteers
- 250 people
- Sponsor
- Charite University, Berlin, Germany
Quality of Life
Evaluating the Effects of Psycho-oncological Education on Distress and Quality of Life in Solid Tumor Cancer Patients
This study evaluates that effects of psycho-oncological education on distress and quality of life in solid tumor cancer patients who have completed chemotherapy with curative intent.
- Trial name
- NCT02370836
- Testing
- Education
- Volunteers
- 28 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Breast Cancer, Comorbidities and Coexisting Conditions
Streamlined Geriatric and Oncological Evaluation Based On IC Technology
The primary objective of GERONTE STUDY is to evaluate the effectiveness of the GERONTE, ICT-based, integrated care pathway to improve patient 6-month quality of life, in France.
- Conditions
- Breast Cancer, Comorbidities and Coexisting Conditions, Lung Cancer, Colorectal Cancer
- Trial name
- FRONE (NCT05720910)
- Testing
- GERONTE
- Where
- 11 sites in France
- Volunteers
- 720 people
- Sponsor
- Institut Bergonié
Hepatitis E Infection, Hepatitis; Epidemic
Hepatitis E Virus Infection in Oncological Patients
The goal of this clinical trial is to investigate the prevalence of hepatitis E infection in oncological patients in a rural region of Germany.
- Conditions
- Hepatitis E Infection, Hepatitis; Epidemic, Oncologic Disorders
- Trial name
- HepE-Onko-BB (NCT06631560)
- Testing
- ELISA testing
- Where
- Germany
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Pain, Depression Anxiety Disorder
Hypnosis in Pain Management, Anxiety and Depression in Oncological Patients
The aim of this trial is to compare and evaluate the effects of hypnosis in cancer patients, to reduce the level of pain, anxiety and depression.
- Trial name
- HPMADOP (NCT02105740)
- Testing
- Hypnosis, Control
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Gil Montenegro
Gastric Cancer, Obesity
Compare the Oncological Benefit of Deep Neuromuscular Block in Gastric Cancer Obesity Patient
This study is designed to evaluate the impact of muscle relaxation during laparoscopic gastrectomy on oncological benefit, especially with obese patients over BMI 25.
- Trial name
- NCT03196791
- Testing
- Sugammadex Sodium
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Korea University Anam Hospital
Breast Cancer Female, Osteoporosis
Health and QoL in Oncological Patients: Management of Bone Pathology in Italian Citbl Population
Studying the current state of the clinical approaches to bone diseases in breast cancer patients treated with adjuvant and/or hormone therapy
- Trial name
- NCT04055805
- Testing
- Observational Analysis
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sarcopenia in Elderly, Frailty/Sarcopenia
Frailty in the Elderly Oncological and Oncohematological Patient.
The Italian population is progressively aging, and cancer incidence increases with age. Older patients are at higher risk of frailty, a condition associated with adverse outcomes such as disability, falls, hospitalization, and…
- Conditions
- Sarcopenia in Elderly, Frailty/Sarcopenia, Oncological Patients, Hematologic Disease
- Trial name
- SALICE (NCT07624370)
- Testing
- Frailty evaluation
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano
Breast Cancer
The Involvement of Breast Cancer Patients During Oncological Consultations
The main aim of the study is to assess if a pre consultation intervention facilitates greater participation of patients (and accompanying key persons when present) in the consultation process by determining an increase in…
- Trial name
- INCA (NCT01510964)
- Testing
- prompt-sheet, control group
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Cancer Cachexia
PSYCHO-EDUCATIONAL AND REHABILITATIVE INTERVENTION FOR CANCER CACHEXIA (PRICC)
Half of all cancer patients experience cachexia, with the prevalence rising above 80% in the last weeks of life. The cancer cachexia is a complex relational experience which involves the dyads patients-families.
- Trial name
- NCT04153019
- Testing
- Psychoeducational and rehabilitative intervention
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Leukemia
SubCutaneous (SC) Versus Intravenous (IV) Granulocyte Colony Stimulating Factors (G-CSF) for the Treatment of Neutropenia in Hospitalized Haemato-oncological Patients
Granulocyte colony stimulating factor (G-CSF) is frequently used among patients with cancer including those with haematological malignancies.
- Trial name
- G-CSF (NCT01222819)
- Testing
- filgrastim
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Rabin Medical Center
Cancer, Pain
Oxycodone and Pregabalin for the Treatment of Oncological Neuropathic Pain
The aim of the study is to assess tolerability and activity of oxycodone and pregabalin in combination for the treatment of oncological neuropathic pain with two different strategies.
- Trial name
- NCT00637975
- Testing
- oxycodone, pregabalin
- Where
- 8 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Associazione Progetto Oncologia UMAN.A
Cancer Patients and Physical Activity
Dance Movement Therapy for Radio-oncological Patients
Dance-RT-01 investigates the feasibility and effects of Integrative, resource-oriented short term Dance Movement Therapy (DMT) in radio-oncological patients shortly after radiotherapy (RT).
- Trial name
- DANCE-RT-01 (NCT07001033)
- Testing
- Dance Movement Therapy (DMT)
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Haemato-oncological Paediatric Patients Under Intensive Chemotherapy
New Biomarkers for Invasive Fungal Infections in Paediatric Haemato-oncology
The availability of sensitive and specific fungal biomarkers could be a precious help to improve the management of patients suffering from fungal diseases, not only by allowing preemptive treatment, but also by offering objective…
- Trial name
- NCT02587377
- Testing
- Non Standard of Care blood samples collection
- Volunteers
- 20 people
- Sponsor
- Queen Fabiola Children's University Hospital
Oncologic Complications
Ambispective Observational Multicenter Study on the Efficacy of the Third Dose of Vaccine Anti COVID-19 in Patients Suffering From Solid Tumors Undergoing Oncological Treatment Active.
To evaluate the serum neutralizing antibody titre in cancer patients undergoing active treatment against variants (VOC) before and after the third dose of BNT162b2 COVID-19 vaccine.
- Trial name
- NCT06334744
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Pain, Postoperative
PIEB-PCEA vs CEI-PCEA for Abdominal Oncological Surgery. A Randomized Prospective Clinical Trial
The aim of the study is to compare programmed intermittent bolus application and continuous epidural infusion with regard to additionally applied patient-controlled volume of local anesthesia and quality of analgesia.
- Trial name
- PIEB (NCT03378804)
- Testing
- Programmed intermittent epidural bolus application (PIEB), Continous epidural analgesia
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- Philipps University Marburg
Pain Management, Opoid Managment
ESP vs Retrolaminar Block: A Randomized Trial
The study aims to compare the efficacy in pain control and total opioid consumption after the use of ESPB and retrolaminar block in patients undergoing major oncological breast surgery..
- Trial name
- NCT07200960
- Testing
- ESPB
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre