Clinical trials: PCA
Prostate Cancer, PET/CT
Head-to-head Comparison of [18F]AlF-PSMA-N5 With [18F]F-DCFPyL PET/CT in PCa Diagnosis, Recurrence, and Metastasis
To prospectively evaluate the radiodrug biodistribution of a novel PET imaging agent [18F]AlF-PSMA-N5 in different organs of prostate cancer patients and its diagnostic efficacy in the diagnosis, recurrence and metastasis of…
- Trial name
- NCT06756334
- Testing
- [18F]AlF-PSMA-N5, [18F]F-DCFPyL
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
PCA, Prostate Cancer
PSMA PET Combined With MRI for the Detection of PCa
This is an open label, longitudinal Phase 3 study of prostate specific membrane antigen (PSMA) positron emission tomography (PET) combined with magnetic resonance imaging (MRI) compared to standard of care (SOC) for the detection…
- Conditions
- PCA, Prostate Cancer, Prostatic Neoplasm, PSMA PET
- Trial name
- BiPASS (NCT07052214)
- Testing
- 68Ga-PSMA-11
- Where
- 18 sites in United States, Australia
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
Pain, Postoperative
Comparison of Post-operative Pain in Short Versus Long Stitch for Laparotomy Closure
Laparotomy is a surgical procedure where an incision is made through the abdominal wall in order to gain access to the peritoneal cavity. Midline laparotomy incisions were the main type of abdominal access.
- Trial name
- Shortstitch (NCT03828409)
- Testing
- Short stitch, Long stitch
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Labour
Systematic Clonidine for Epidural Analgesia in Labour
In a prospective randomised study involving primiparous women in spontaneous uncomplicated labour with cervical dilatation < 5 cm, epidural analgesia will be given with an initial volume of 20 mL anaesthetic solution, followed by…
- Trial name
- NCT00983125
- Testing
- Clonidine
- Where
- France
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Quality of Recovery, Elective Cesarean Section
Evaluating The Quality of Recovery After Elective Cesarean Section
Adequately validated patient-reported outcome measures are available, which can assess recovery profiles following childbirth. This study will explore the effect of two different methods for pain management on the quality of…
- Conditions
- Quality of Recovery, Elective Cesarean Section, Quadratus Lumborum Block, Patient Controlled Analgesia
- Trial name
- NCT06155968
- Testing
- QL block, PCA
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Diet Surveys, Food Preferences
Gender Differences in Dietary Patterns and Physical Activity: A PCA Approach
This study investigates gender differences in dietary patterns and physical activity using Principal Component Analysis (PCA). It aims to identify distinct eating and activity behaviors between men and women in order to develop…
- Trial name
- GENDPCA (NCT06654674)
- Where
- Italy
- Volunteers
- 2,509 people, healthy volunteers welcome
- Sponsor
- San Raffaele Telematic University
Diabetes Mellitus, Type 2
A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Pyroglutamate Rongliflozin Capsules in Subjects With Mild and Moderate Liver Damage
To evaluate the pharmacokinetic characteristics of pyroglutamate rongliflozin capsules in subjects with mild and moderate liver damage and healthy subjects
- Trial name
- NCT05427682
- Testing
- pyroglutamate rongliflozin capsules
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Pain Management, Analgesia
Post-Operative Pain Management Following Spine Surgery
The primary objective of this pilot study is to assess the feasibility of comparing two standardized approaches to manage post-operative pain following spine surgery: one approach using Patient Controlled Analgesia (PCA) devices…
- Conditions
- Pain Management, Analgesia, Anesthetic
- Trial name
- EXPAREL (NCT03076710)
- Testing
- Opioids delivered through PCA, EXPAREL® infiltration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Postoperative Pain Management
Assessment of Healthcare Professionals' Knowledge and Attitudes Toward Patient-Controlled Analgesia
Patient-controlled analgesia (PCA) is a widely used method for postoperative pain management that allows patients to self-administer analgesics according to their pain needs.
- Trial name
- NCT07359118
- Testing
- Patient-Controlled Analgesia Educational Program
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Analgesia
Epidural Anesthesia /Analgesia Versus PCA for Laparoscopic Complex Ventral Hernia Repair: A Randomized Controlled Trial
We plan to demonstrate the superiority of epidural anaesthesia/analgesia in repairs of large ventral hernias as compared with a conventional narcotic analgesia regimen. We hypothesize that: 1.
- Trial name
- NCT00529074
- Testing
- Epidural Catheter for Analgesia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Diabetes Mellitus, Type 2
Correlation Between the Pulmonary Function Parameters and the Circulatory Parameters (PSV, EDV, RI) of Retrobulbar Blood Vessels (CRA, PCA, and OA) in 48 T2DM Patients Did Not Combinate With DR
Objective: The main target of this study was to research the correlation between the pulmonary function and the circulatory parameters of retrobulbar blood vessels in patients with type 2 diabetes (T2DM) without diabetic…
- Trial name
- CPCT2DM (NCT02774733)
- Testing
- spirometer;Intraocular pressure;Color doppler imaging
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fourth People's Hospital of Shenyang
Pain, Postoperative
Erector Spina Plane Block Volume Comparison
After obtaining ethical committee approval from Kahramanmaras University Anesthesiology and Reanimation Department and Urology Clinic, 60 patients between 18-65 years old who meet ASA I-II classification criteria with body mass…
- Trial name
- NCT06332313
- Testing
- erector spina plane block
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Prostate Cancer, PET/CT
Head-to-head Comparison of [68Ga]Ga-PSMA-D5 With [68Ga]Ga-PSMA-11 PET/CT in PCa Diagnosis, Recurrence, and Metastasis
To prospectively evaluate the radiodrug biodistribution of a novel PET imaging agent [68Ga]Ga-PSMA-D5 in different organs of prostate cancer patients and its diagnostic efficacy in the diagnosis, recurrence and metastasis of…
- Trial name
- NCT05955677
- Testing
- [68Ga]Ga-PSMA-D5, [68Ga]Ga-PSMA-11
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Postoperative Pain, IL-1 Beta
Comparison of the Ultrasound Guided Effects of the Erector Spina Plane Block and Quadratus Lumborum Block Methods on Postoperative Analgesia and Plasma Cytokine Levels in Elective Cesarean Operations
Comparison of Two Different Analgesic Techniques for Reducing Postoperative Pain After Cesarean Section
- Trial name
- NCT07901829
- Testing
- QL (quadratus lumborum) block, Erector Spinae Plane Block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Education and Research Hospital
Analgesia
Efficiency and Safety a Fixed Combination of Orphenadrine and Diclofenac for Postoperative Analgesia
The study will include 60 patients after cardiac surgery. The first group will include 30 patients who will use the drug Neodolpasse manufactured by Fresenius Kabi, which is a fixed combination of 30 mg of orphenadrine and 75 mg…
- Trial name
- NCT05322603
- Testing
- Analgesics Non Opioid (Neodolpasse manufactured by Fresenius Kabi), Analgesics
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Petrovsky National Research Centre of Surgery
Total Knee Arthroplasty
The Analgesic Effect of Nitroglycerin Patch for Postoperative Pain After Total Knee Replacement
Patients who undergo general anestheesia for total knee arthroplasty pften have sever postoperative pain which hinders their rehabilitation.
- Trial name
- NCT00375362
- Testing
- Nitroderm patch
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Postoperative Pain
The Postoperative Analgesic Effect of Combination With Dexmedetomidine in Fentanyl-based Intravenous Patient Controlled Analgesia Compared With Conventional Thoracic Epidural and Intravenous Patient Controlled Analgesia After Radical Open Gastrectomy
The aim of this study to test hypothesis that addition of dexmedetomidine to fentanyl based intravenous patient controlled analgesia (PCA) improves postoperative pain compared with conventional thoracic epidural and intravenous…
- Trial name
- NCT02325882
- Testing
- Dexmedetomidine, Fentanyl 1, Fentanyl 2
- Where
- South Korea
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Taste Sensitivity, Umami Taste Perception
Umami Taste Intensity and Meal Intake
Sweet and salty tastes can influence food intake. Increased intensity of these tastes has been shown to decrease food intake and increase satiation compared to the less intense taste, independent of palatability.
- Conditions
- Taste Sensitivity, Umami Taste Perception, Food Intake Regulation, Hedonic Function
- Trial name
- OptUmami (NCT07421466)
- Testing
- Hedonic mapping, Ad libitum risotto test meal
- Where
- Netherlands
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Analgesic Quality, Mobility
Observational Study of Analgesia and Cost-efficiency of Analgetic Medication Pumps (Zalviso and PCA-syringe Pump (PCA=Patient Controlled Analgesia)) After Urogenital Intervention at the Clinical Daily Routine
The observational study will check if there is a difference in the postoperative care of patients with urogenital intervention while using the standard PCA-syringe pump or using the Zalviso sufentanyl sublingual analgetic system.
- Trial name
- NCT03355352
- Testing
- Sufentanil
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Anesthesia, Acute Pain
Comparative Effects of Ciprofol and Propofol on Pain Intensity on the First Day After Surgery: a Retrospective, Propensity Score Matched, Cohort Study
Data intelligence platform was widely used to facilitate the process of clinical research. However, a platform that integrates natural language processing (NLP) and machine learning (ML) algorithms has not been reported in…
- Conditions
- Anesthesia, Acute Pain, Risk Reduction
- Trial name
- NCT06020469
- Where
- China
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- Guangdong Second Provincial General Hospital