Clinical trials: Postoperative Knee Function
Pain, Total Knee Replacement
Analysis of Postoperative Analgesic of Different Nerve Blocks for Total Knee Replacement Surgery
This study is a retrospective analysis using the accumulated clinical database from 2017/09-2023/12 to analyze patients who underwent total knee arthroplasty and received nerve blocks.
- Conditions
- Pain, Total Knee Replacement, Motor Function
- Trial name
- NCT06521619
- Testing
- Femoral and sciatic nerve blocks
- Where
- Taiwan
- Volunteers
- 126 people
- Sponsor
- Fu Jen Catholic University Hospital
Anterior Cruciate Ligament Rupture
Evaluation After Reconstruction of the Anterior Cruciate Ligament of the Knee Using the Bioresorbable Interference Screw (SMS): Resorbability, Per- and Post-operative Complications and Articular Functional Recovery.
The investigators will evaluate the benefit of a new bioresorbable screw for repair of anterior cruciate ligament over 3 years.
- Trial name
- BIORELICA (NCT03529552)
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Central Sensitisation, Postoperative Pain
Evaluation of the Effect of Central Sensitivity on Pain and Functional Status After Total Knee Joint Replacement Surgery
The study is a prospective observational study designed to determine the effects of central sensitization on pain and functional status of patients before and after total knee joint replacement surgery.
- Conditions
- Central Sensitisation, Postoperative Pain, Arthritis
- Trial name
- NCT06553118
- Testing
- Total knee arthroplasty
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Pain
Effects of Sustained-release Oral Sodium Nitrite on Postoperative Pain and Recovery Following Total Knee Arthroplasty
This study will determine whether a drug called sodium nitrite helps improve pain and post-operative recovery associated with knee replacement surgery.
- Trial name
- NCT05893160
- Testing
- JAN101 SR
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis
Kinematic Analysis of a PS, FB Primary Total Knee Arthroplasty (ATTUNE Knee System) Using Dynamic RSA
Background: Across the European Union there are 535,000 Total Knee Arthroplasty (TKA)per year. Statistics indicate that for patients over 60 year old approximately one out of 20 will require corrective reoperations within 10…
- Trial name
- Attune-RSA (NCT02323386)
- Testing
- Primary Total Knee Arthroplasty (ATTUNE Knee System)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Arthroplasty, Replacement Material
Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)
Approximately 20-30% of patients experience persistent pain after a Total Knee Arthroplasty (TKA). This study investigates whether percutaneous cryoneurolysis of genicular nerves can reduce pain and improve physical function when…
- Conditions
- Arthroplasty, Replacement Material, Knee Arthritis Osteoarthritis, Knee Arthroplasty, Total
- Trial name
- CRYO-TKA (NCT07425457)
- Testing
- CT-guided Cryoneurolysis of the Genicular Nerves
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Ligament Injury, Ligament Rupture
Knee Functionality Recovery Indicators in Athletes Submitted to Ligamentoplasty of the Anterior Cruciate Ligament
Anterior cruciate ligament (ACL) injuries are recurrent, especially in sports. There is still no consensus on the characterization of functional indicators in this clinical condition, as well as their correlation with measuring…
- Conditions
- Ligament Injury, Ligament Rupture, Ligament Disorders
- Trial name
- NCT06050005
- Testing
- Diagnostic test through functional tests and comparison of scales applied to participants in the pre-surgical and post-surgical period.
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Total Knee Replacement, Post Operative Pain
Effect of Mindfulness on Pain After Total Knee Arthroplasty
This study will be a prospective randomized controlled trial evaluating the effectiveness of using Headspace before and after undergoing total knee replacement surgery.
- Conditions
- Total Knee Replacement, Post Operative Pain, Opioid Use
- Trial name
- NCT06118073
- Testing
- Headspace, Total Knee Replacement
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Adductor Canal Block, Total Knee Replacement Surgery
Coupling of IPACK Block With Adductor Canal Block Versus Adductor Canal Block Alone on Pain, Functional Recovery and Inflammatory Response After Knee Replacement
The aim of this study is to compare the Competency of coupling of IPACK Block with Adductor Canal Block versus Adductor Canal Block Alone on Postoperative Pain after total knee replacement as well as Functional Recovery and…
- Conditions
- Adductor Canal Block, Total Knee Replacement Surgery, Functional Recovery
- Trial name
- NCT07096375
- Testing
- Adductor Canal Block (ACB) + iPACK Block
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Knee Osteoarthritis, Total Knee Arthroplasty
Effect of Preoperative Cold Therapy on Early Postoperative Outcomes in Total Knee Arthroplasty
This prospective, single-center, randomized controlled trial investigates the effects of preoperative cold therapy on early postoperative outcomes in patients undergoing unilateral primary total knee arthroplasty (TKA).
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Cryotherapy, Postoperative Pain Management
- Trial name
- NCT07134283
- Testing
- Preoperative and Postoperative Cold Therapy with Gel Cold Pack, Postoperative Cold Therapy with Gel Cold Pack
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people
- Sponsor
- Ankara City Hospital Bilkent
Total Knee Arthroplasty
The Relationship Between Preoperative Serum Cytokine Level and Lenght of Stay in Hospital, Postoperative Pain Intensity, Functional Status, Joint Position Sense and X Ray Findings
Serum cytokines was assosiated with symptoms and progression of osteoartritis. It is unknown whether these cytokines have a predictive role on severity of symptoms after total knee arthroplasty (TKA) or not.
- Trial name
- NCT04487535
- Testing
- Cytokine level
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Hacettepe University
Knee Arthropathy, Post Operative Pain
Function and Pain Following Knee Replacement
The goal of this interventional study is to compare pain management techniques (femoral nerve block, intra-articular block, none) in TKA patients.
- Conditions
- Knee Arthropathy, Post Operative Pain, Pain, Postoperative
- Trial name
- NCT05478005
- Testing
- Femoral nerve block, Intra-articular block
- Where
- Israel
- Volunteers
- 54 people
- Sponsor
- University of Haifa
Osteoarthritis
Effect of Tourniquet Application on Postoperative Functional Outcome Following Total Knee Arthroplasty
A pneumatic tourniquet is often used during total knee arthroplasty. However, its effect on postoperative outcomes as soft tissue damage resulting in delayed recovery remains unclear.
- Trial name
- NCT02308410
- Testing
- Tourniquet application during surgery
- Where
- 2 sites in Netherlands
- Volunteers
- 99 people
- Sponsor
- Medicort Sports & Orthopedic Care
Post-Operative Pain Management
Study to Evaluate Iovera®° in Adult Patients Undergoing Total Knee Arthroplasty
Primary objective: The primary objective of this study is to evaluate postsurgical pain control, after presurgical iovera° treatment plus EXPAREL® and standardized multimodal therapy compared with presurgical sham iovera°…
- Trial name
- NCT04191031
- Testing
- ioveraº
- Where
- 7 sites in United States
- Volunteers
- 79 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Arthropathy, Osteoarthritis, Hip
Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty
The aim of this study is to compare the effectiveness of Virtual Reality therapy (VR therapy), Non-Sleep Deep Rest relaxation (NSDR relaxation) each delivered as an adjunct to standard postoperative rehabilitation, in older…
- Conditions
- Arthropathy, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT07386561
- Testing
- Immersive Virtual Reality Therapy, Non-Sleep Deep Rest Relaxation, Conventional rehabilitation
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Osteoarthritis (OA) of the Knee
Comparison of Postoperative Functional Outcomes Between Subvastus and Medial Parapatellar Approach in Total Knee Arthroplasty
This study aims to compare the effects of the medial parapatellar approach (MP) and the subvastus approach (SV) on postoperative clinical function in total knee arthroplasty (TKA).
- Trial name
- NCT07742696
- Testing
- subvastus, medial parapatellar
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Peking University Third Hospital
ACL Injury, ACL Reconstruction
Comparative Effectiveness of Blood Flow Restriction With or Without Total Motion Release in ACL Rehabilitation
The aim of this clinical trial is to compare the effectiveness of combined Blood Flow Restriction (BFR) and Total Motion Release (TMR) versus BFR alone in the restoration of muscular strength, balance and knee functionality in…
- Trial name
- BFR-TMR-ACL (NCT07589309)
- Testing
- Blood Flow Restriction, Total Motion Release
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Green International University
Postoperative Pain, Functional Outcomes
Adductor Canal Block Versus Femoral Nerve Block With Repeated Bolus Doses Arthroplasty
After total knee prosthesis surgery, in the first postopertive days, serious pain complaints occur in the patients and this causes many problems, especially mobility limitation. For this reason, a strong analgesic is needed.
- Trial name
- NCT03188809
- Testing
- Adductor Canal Block, femoral nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Kecioren Education and Training Hospital
Osteo Arthritis Knee
Tranexamic Acid in Total Knee Replacement
Multiple intravenous Tranexamic Acid doses can reduce postoperative blood loss and improve the functional outcome in total knee arthroplasty without tourniquet: a randomized controlled study.
- Trial name
- NCT03656445
- Testing
- Tranexamic Acid
- Volunteers
- 180 people
- Sponsor
- Democritus University of Thrace
Postoperative Pain After Arthroscopic Knee Surgery
Adductor Canal Block Versus Parasartorial Compartment Block for Pain Relief and Recovery After Arthroscopic Knee Surgery
The goal of this clinical trial is to compare adductor canal block and parasartorial compartment block for pain relief and functional recovery in adults undergoing elective arthroscopic knee surgery.
- Trial name
- NCT07790393
- Testing
- Meperidine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital