Clinical trials: Quality of Recovery
Opioid Free Anesthesia, Opioid Based Anesthesia
Intraoperative Infusion of Dexmedetomidine Versus Lidocaine or Magnesium Sulphate for Enhanced Quality of Recovery After Spine Surgery Fixation
Thoracolumbar fixation is a major spine surgery; it is performed to stabilize the spine after trauma, deformity or advanced degenerative disease.
- Conditions
- Opioid Free Anesthesia, Opioid Based Anesthesia, Spine Fixation Surgeries, Opiod-Related Disorders
- Trial name
- NCT07843953
- Testing
- Group ( L): LICOCAINE, GROUP Dexmedetomidine, Group M: Magnesium sulphate
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Sleep Wake Disorders, Esketamine and the Quality of Recovery
Clinical Study of Perioperative Sleep Disorders in Cardiac Surgery
The aim of this clinical trial is to understand the effects of dexmedetomidine and esketamine on postoperative sleep in patients undergoing cardiac surgery.
- Conditions
- Sleep Wake Disorders, Esketamine and the Quality of Recovery, Dexmedetomidine
- Trial name
- NCT06778811
- Testing
- Intraoperative infusion of dexmedetomidine, Intraoperative infusion of esketamine, Saline control
- Where
- 2 sites in China
- Volunteers
- 180 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Osteo Arthritis Knee and Hip, Osteo Arthritis
General Anaesthesia vs Spinal Anaesthesia: Patient Outcomes and Success in Outpatient Primary Total Knee and Hip Arthroplasty
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are common operations used to treat severe joint disease, most often caused by osteoarthritis.
- Conditions
- Osteo Arthritis Knee and Hip, Osteo Arthritis, Inflammatory Joint Disease (IJD)
- Trial name
- GASPS (NCT07334132)
- Testing
- General Anaesthesia, Spinal Anesthesia (bupivacaine)
- Volunteers
- 600 people
- Sponsor
- Region Örebro County
Parkinson's Disease
Long-term Extension of RECOVER- Long-term Effect of the 24h Transdermal Delivery of Rotigotine in Subjects With Idiopathic Parkinson's Disease
The objective of this open-label extension is to assess the long-term effect of the 24-hour transdermal delivery of rotigotine on motor function, sleep quality, and nocturnal and non-motor symptoms of Parkinson's disease.
- Trial name
- NCT00519532
- Testing
- Rotigotine
- Where
- 21 sites in United States, Australia and 9 more
- Volunteers
- 84 people
- Sponsor
- UCB Pharma
Postoperative Pain, Postoperative Nausea and Vomiting
Low Doses of Ketamine and Postoperative Quality of Recovery
There are evidences that intraoperative administration of low doses of ketamine may contribute to control the postoperative pain by acting on the N-methyl-D-aspartate (NMDA) channel, reducing the effects related to the tolerance…
- Trial name
- NCT02571153
- Testing
- Ketamine 0.4 mg/kg, Normal saline, Ketamine 0.2 mg/kg
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Esmolol Adverse Reaction
Efficacy of Esmolol Versus Magnesium Sulphate on Quality of Recovery in Patients Undergoing Laparoscopic Cholecystectomy: Randomized Controlled Study
sixty patients, of both sexes, of ASA I or II planned for ambulatory laparoscopic cholecystectomy under general anaesthesia were engaged into 2 groups.
- Trial name
- NCT05850832
- Testing
- Esmolol, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Sleep Disorder
Association Between Preoperative Insomnia and Postoperative Quality of Recovery : A Prospective Observational Study
Although patients with cancers are prone to insomnia, especially waiting for surgery during hospitalization, and insomnia promotes acute respiratory infections (ARI) and is not conducive to the postoperative quality of recovery…
- Trial name
- PIPQoR (NCT06008873)
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis
Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?
The primary objective of the present research is to determine the effectiveness of Family Health Center of San Diego's Long COVID and Fatiguing Illness Recovery Program (LC\&FIRP) on clinician- and patient-level outcomes.
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 Infection
- Trial name
- LC&FIRP (NCT05167227)
- Testing
- Extension for Community Healthcare Outcomes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Family Health Centers of San Diego
Lung Neoplasms, Thoracic Surgery Lung
Telerehabilitation Exercise Program for Postoperative Recovery in Lung Cancer.
Lung cancer is one of the leading causes of cancer-related morbidity and mortality worldwide. Thoracic surgery remains the treatment of choice for patients with early-stage disease; however, postoperative recovery is frequently…
- Trial name
- TEPUL (NCT07861282)
- Testing
- Therapeutic Exercise-Based Telerehabilitation, Usual Postoperative Care
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- University of Seville
Bladder Cancer, Postoperative Pain Management
Retrospective Analysis of Different Quadratus Lumborum Block Techniques on Recovery Quality and Analgesic Consumption in Radical Cystectomy Patients
This retrospective observational study evaluates the effects of different Quadratus Lumborum Block (QLB) techniques on postoperative recovery and total opioid consumption in patients undergoing radical cystectomy under general…
- Conditions
- Bladder Cancer, Postoperative Pain Management, Opioid Consumption, Recovery Quality
- Trial name
- QLB-CYS (NCT06851520)
- Testing
- Anterior Quadratus Lumborum Block (QLB), Posterior Quadratus Lumborum Block (QLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Namik Kemal University
Postoperative Pain
Comparison of the Effects of Retro Laminar Block (RLB) and Erector Spina Area Block (ESP) on Postoperative Recovery Quality and Pain in Lumbar Spinal Surgery
The aim of this study is to compare the efficacy of erector spinae plane block (ESPB) and Retrolaminar Block on postoperative recovary quality and pain after lumbar spinal surgery
- Trial name
- NCT05792124
- Testing
- Erector spina area block, Retrolaminar block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Aydin Adnan Menderes University
Adult Liver Carcinoma, Caregiver
Walking for Recovery From Surgery in Improving Quality of Life in Older Adults With Lung or Gastrointestinal Cancer and Their Family Caregivers
This pilot clinical trial studies how well Walking for Recovery from Surgery works in improving quality of life in older adults with lung or gastrointestinal cancer and their family caregivers.
- Conditions
- Adult Liver Carcinoma, Caregiver, Colorectal Carcinoma, Lung Carcinoma
- Trial name
- NCT03267524
- Testing
- Exercise Intervention, Quality-of-Life Assessment, Survey Administration
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Cholecystitis
Efficacy Of M-TAPA and TAP Block Following Laparoscopic Cholecystectomy
Cholecystectomy is the most common abdominal surgical procedure in developed countries Laparoscopic cholecystectomy is considered the gold standard surgical technique for gallstones.
- Trial name
- NCT06198335
- Testing
- Modified Perichondral Approach Thoracoabdominal Nerve block, Transversus Abdominal Plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mursel Ekinci
Opioid Consumption, Quality of Recovery(QoR-40), Preoperative and Postoperative
The Effects of ESP Block and Mid-Transverse Process to Pleura Block on Postoperative Opioid Consumption and Quality of Recovery
Erector Spinae Area (ESP) Block and Mid-Transverse Process to Pleura Block(MTP) have recently been described for the treatment of pain after lumbar spinal surgery.
- Trial name
- NCT06815146
- Testing
- Numeretic rating scale (NRS), Quality of Results (QoR-40), Opioid consuption
- Volunteers
- 126 people
- Sponsor
- Aydin Adnan Menderes University
Achievement of High-quality Analgesia, Rapid Recovery With Rehabilitation in Lumber Spine Discectomy
Erector Spinae Plane Block Versus Modified Thoracolumbar Interfascial Plane Block
the purpose of this study is to compare of better postoperative analgesia following lumber spine discectomy
- Trial name
- NCT06910696
- Testing
- Regional Anesthetic Injection
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Zagazig University
Quality of Life, Obstetric Complication
Evaluation of the Relationship Between Obstetric Comorbidity Index and Obstetric Quality of Recovery Score
The goal of this prospective observational study is to learn about the correlation between obstetric comorbidity index and obstetric quality of recovery score in pregnant patients who undergo cesarean section.
- Conditions
- Quality of Life, Obstetric Complication, Cesarean Section Complications, Comorbidities and Coexisting Conditions
- Trial name
- NCT05704179
- Testing
- Obstetric Quality of recovery score
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Cervical Myelopathy, Ossification of Posterior Longitudinal Ligament in Cervical Region
The Establishment of the Integration of Surgery and Postoperative Intensive Recovery of Patients With CSM
This study aims to establish the specialist consensus of the integration of posterior approach surgical treatment and postoperative intensive recovery management for CSM or OPLL patients, and verify its safety, practicability and…
- Trial name
- NCT04947891
- Testing
- Intensive recovery management
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Peking University Third Hospital
Video Assisted Thoracic Surgery (VATS), Pain Management
QoR40 Between Intercostal Block and Intercostal Block and Serratus Plane Catheter During VATS
Video assisted thoracic surgery (VATS) has emerged as standard of care for majority of thoracic surgeries. It is less invasive compared to thoracotomy and is associated with improved perioperative outcomes [1-3].
- Trial name
- NCT04990713
- Testing
- Serratus Plane Block (Local Anesthetic) and Intercostal Block (Local Anesthetic)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Nerve Block, Nephrectomy, Analgesia
QLB Versus PVB for Acute Pain and Quality of Recovery After Laparoscopic Partial Nephrectomy
This trial is a prospective, randomized, single-center, open-label, parallel-arm, blinded-analysis trial, the objective of which is to evaluate the effect of transmuscular quadratus lumborum block (TMQLB) in the pain relief and…
- Trial name
- NCT03975296
- Testing
- preoperative single-shot TMQLB, preoperative single-shot TPVB, patient controlled intravenous analgesia(PCIA)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Cui Xulei
Femoral Neck Fractures
Recovery of Physical Functioning After Hip Fracture
The survivors after hip fracture often report severe pain and loss of physical functioning. The poor outcomes cause negative impact on the person's physical functioning and quality of life and put a financial burden on society.
- Trial name
- HIPFRAC (NCT02780076)
- Testing
- Functional training program
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Vestre Viken Hospital Trust