Clinical trials: Stroke Volume Index
Hemorrhage
Comparison of Compensatory Reserve Index to Intravascular Volume Change and Stroke Volume
This study is designed to validate implementation of the CRI algorithm in the CypherOx CRI system. Healthy human subjects will undergo progressive reduction in central blood volume to the point of hemodynamic instability (defined…
- Trial name
- NCT01935427
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Flashback Technologies
Goal Directed Fluid Therapy
Stroke Volume Variation and Plethysmography Variability Index as Goal Directed Fluid Therapy in Major Oncosurgeries
Patients were allotted to two Groups , SVV Guided Fluid Therapy Group received intraoperative fluids to maintain SVV <11 , and PVI Guided Group received intraoperative Fluids to maintain PVI<11
- Trial name
- SVV PVI GDFT (NCT05142163)
- Testing
- Intraoperative SVV Guided Fluid Therapy, Intraoperative PVI Guided Fluid Therapy
- Where
- India
- Volunteers
- 68 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Perioperative Care, Fluid Therapy
Paired Comparison of SVV and PVI Accuracy
This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a…
- Conditions
- Perioperative Care, Fluid Therapy, Monitoring, Physiologic, Hemodynamics
- Trial name
- NCT07260890
- Testing
- Stroke Volume Variation (SVV) monitoring, Pleth Variability Index (PVI) monitoring
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Right Ventricular Dysfunction, Stroke Volume Index
Relationship Between Strain and Stroke Volume in Cardiac Surgery
Patients undergoing coronary artery bypass grafting up tp 30% will develop postoperative right ventricle dysfunction. Its imperative for the physician to fully understand the severity of this complication in order to perform an…
- Conditions
- Right Ventricular Dysfunction, Stroke Volume Index, Longitudinal Heart Strain
- Trial name
- NCT04694378
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tufts Medical Center
Hemodynamic Monitoring
Goal-directed Hemodynamic Therapy in Patiens Undergoing Major Hepatic Resection
The aim of the study of patients undergoing major hepatic resection was compared standard perioperative (control Group) with hemodinamic management based on PPV, VVS, continuos CO trending and dynamic arterial elastance using…
- Trial name
- GOAL-HEMO (NCT04517409)
- Testing
- Goal-directed hemodynamic therapy, Control
- Volunteers
- 45 people
- Sponsor
- Castilla-La Mancha Health Service
Anesthesia, General, Hypotension
Haemodynamic Effects of Four Sevoflurane Wash-In Strategies After Tracheal Intubation
The goal of this clinical trial is to compare how four different ways of starting sevoflurane anaesthesia (the "wash-in" phase) affect the heart and circulation during the first 10 minutes after endotracheal intubation in adults…
- Trial name
- WASH-PRAM (NCT07894393)
- Testing
- End-tidal-controlled sevoflurane wash-in, Low-flow high-concentration wash-in (0.5 L/min, 8% sevoflurane), Low-flow wash-in (1 L/min, 4% sevoflurane)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Ataturk University
Liver Cirrhosis
Dynamic Preload Parameters During Liver Transplantation
The arterial system compliance is compromised in liver cirrhotic patients. Dynamic preload variables are either pressure-based (e.g.pulse pressure variation; PPV), flow-based (e.g.
- Trial name
- NCT01971333
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Cardiac Failure Acute, Hemodynamic Monitoring
Comparison of Cardiac Index and Stroke-volume-index Measured by Pulmonary Artery Catheter, FloTrac® and Argos® in Cardiac Surgery Patients.
A comparison of cardiac performance determined by stroke-volume-index measured by different mechanisms in patients during and after cardiac surgery: 1. Pulmonary artery catheter 2. Flo Trac 3.
- Trial name
- NCT06918301
- Testing
- Measurement of cardiac performance
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Karlsburg Hospital
Hemorrhage
Comparison of Physiological Variables During Blood Donation
The investigators have developed a system based on a pulse oximeter, a tablet, and an algorithm running on the tablet that analyzes the pulse oximeter waveform.
- Trial name
- NCT02029807
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pacemaker Dependence
The Ability of Peripheral Perfusion Index To Detect Changes of Hemodynamics in Patients With Pacemaker
Pacemakers are widely used in postcardiotomy patients to avoid severe arrhythmia. The peripheral perfusion index (PI) has been considered as an effective parameter evaluating the circulation.
- Trial name
- NCT04952649
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Zhongshan Hospital
Anesthesia, Perioperative/Postoperative Complications
Use of Heart-lung Interaction to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP
This is an observational, prospective, single-centre study that will focus on patients undergoing major non-cardiac surgery requiring invasive mechanical ventilation and invasive blood pressure monitoring Hypotheses: A positive…
- Conditions
- Anesthesia, Perioperative/Postoperative Complications, Hypovolemia, Haemodynamic Instability
- Trial name
- HiPEEP (NCT06123039)
- Testing
- Tidal Volume Challenge, Recruitment maneuver obtaining individualised PEEP
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Kidney Transplant; Complications, Renal Failure Chronic
Comparison of Two Different Preload Targets of Stroke Volume Variation During Kidney Transplantation
The investigators sought to compare the effect of two preload targets of stroke volume variation of ≤6% and ≤12% on the postoperative renal function in patients undergoing living donor kidney transplantation.
- Trial name
- NCT03949036
- Testing
- Crystalloid fluid administration with the target of stroke volume variation ≤ 12%, Crystalloid fluid administration with the target of stroke volume variation ≤ 6%
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Bladder Cancer, Radical Cystectomy
The Effect of Goal-directed Hemodynamic Therapy in Radical Cystectomy
Goal-directed therapy (GDT) has been applied to various clinical settings and has been widely researched recently as a method for perioperative management of patients.
- Trial name
- NCT03505112
- Testing
- Goal-directed therapy
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Seoul National University Hospital
Cardiac Disease
Impact of High Mechanical Index Ultrasound Impulses on Left Ventricular Stroke Volume With Intravenous Microbubbles
This study will investigate whether applying high mechanical index (MI) impulses from a diagnostic ultrasound transducer when using ultrasound enhancing agent (UEA) microbubble infusion will result in subclinical improvement in…
- Trial name
- MI (NCT05700032)
- Testing
- high MI impulses, low MI impulses
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Thoracoscopic Lobectomy, Thoracic Anesthesia
Goal-Directed Fluid Therapy for Thoracoscopic Lobectomy
The investigators aimed to examine the effect of goal-directed fluid therapy (GDFT) compared to conventional fluid therapy in thoracoscopic lobectomy surgery with ERAS protocol on intraoperative pulmonary oxygenation and 30-day…
- Conditions
- Thoracoscopic Lobectomy, Thoracic Anesthesia, Enhanced Recovery After Anesthesia, Lung Cancer
- Trial name
- NCT07050979
- Testing
- Goal-Directed Fluid Therapy (GDFT), Conventional Fluid Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Acute Decompensated Heart Failure
Change in Stroke Volume Index After Diuresis for Patients With Decompensated Heart Failure
This is a prospective cohort study for 50 patients admitted to the cardiac care unit requiring clinically-indicated diuretic therapy for congestive heart failure.
- Trial name
- NCT05240651
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Pulse Pressure Variation, Stroke Volume Variation
Peripheral Venous Pressure Variation, Pulse Pressure Variation and Pleth Variability Index for Fluid Responsiveness
Pulse pressure variation (PPV) and pleth variability index (PVI) are widely used in clinical practice as indicators of the responsiveness to fluid therapy in patients receiving mechanical ventilation.
- Conditions
- Pulse Pressure Variation, Stroke Volume Variation, Pleth Variability Index
- Trial name
- NCT06733389
- Testing
- peripheral waveform collection
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Bundang Hospital
Assessment of Intravascular Volume Status in Mechanically Ventilated Critically Ill Patients
Evaluation of Jugular Venous Distensibility Index in Intravascular Fluid Management and Comparison of the Effectiveness of Noninvasive and Minimally Invasive Methods
Assessment of intravascular volume status is an important component of hemodynamic management in critically ill patients. Several noninvasive and minimally invasive parameters, including the pleth variability index (PVI), pulse…
- Trial name
- NCT07807709
- Testing
- Pleth variability index, Pulse pressure variation, Stroke volume variation
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Sepsis
Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis
Little is known about the optimal fluid therapy of patients with uncomplicated sepsis. Most recommendations are extrapolated from studies performed in patients with septic shock.
- Trial name
- NCT03728998
- Testing
- Passive leg raise (PLR), Clearsight non-invasive hemodynamic monitoring system
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Frisius Medisch Centrum
Post-induction Hypotension, Intestinal Obstruction
SV and IVC Collapsibility Index to Predict Postinduction Hypotension
Postinduction hypotension (PIH) is a frequent complication during general anesthesia. This study aims to compare the predictive effectiveness and diagnostic accuracy of stroke volume (SV) measured via left ventricular outflow…
- Trial name
- NCT07742904
- Volunteers
- 75 people
- Sponsor
- Ain Shams University