Clinical trials: completed
Dry Eye
Preliminary Clinical Study of the Effectiveness and Safety of Ocular Surface Microbiota Transplantation in the Treatment of Dry Eye Disease
Evaluate the efficacy and safety of ocular surface microbiota transplantation as an adjunctive therapy for dry eye, and explore its impact on the structure of the ocular surface microbiota.
- Trial name
- NCT07298811
- Testing
- Ocular surface microbiota transplantation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Hamstring Muscle Shortness and Elastographic Examination
Effects of Dry Needling, Static Stretching and IASTM in People With Hamstring Muscle Shortness
This randomized controlled trial compared the effects of dry needling, static stretching and instrument-assisted soft tissue mobilization (IASTM), each applied three times per week for four weeks, with a no-intervention control…
- Trial name
- NCT04118231
- Testing
- Dry needling, IASTM, Static stretching
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
High School Students
Effects of Nurse-Led School-Based Mental Health Education on Beliefs Toward Mental Illness, Social Distance, and Empathy in Adolescents
This study was aimed to evaluate the effects of a nurse-led, school-based structured mental health education program on adolescents' beliefs toward mental illness, social distance, and empathic tendency.
- Trial name
- NCT07879352
- Testing
- Nurse-Led School-Based Structured Mental Health Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Neslihan Lok
Proprioceptive Neuromuscular Facilitation, Adhesive Capsulitis
PNF and Shoulder Function in Adhesive Capsulitis
This study aimed to investigate the effects of Proprioceptive Neuromuscular Facilitation (PNF) on range of motion, pain, and shoulder function in patients with frozen shoulder.
- Trial name
- NCT07872748
- Testing
- PNF Exercise, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
COVID-19
Variants of SARS-CoV-2 Causing COVID-19 in Africa
The main objective of this research is to identify and characterize the different molecular variants of SARS-CoV-2, emerging and / or circulating in several countries of Sub-Saharan Africa (Burkina Faso, Côte d'Ivoire, Gabon…
- Trial name
- South-Spike (NCT05311891)
- Testing
- RT PCR
- Where
- 6 sites in Burkina Faso, Chad and 4 more
- Volunteers
- 12,600 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Other Gastrointestinal Disorders, Cramp, Abdominal
The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise
Many athletes anecdotally report modifying their nutritional intake before competition in order to avoid gut problems, but no studies have evaluated whether emotional state impacts tolerance to pre-exercise feeding.
- Trial name
- NCT05217589
- Testing
- Funny/Amusing Video Clips, Horror/Scary Video Clips, Thrilling/Suspenseful Video Clips
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Gingival Recession
Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix
The study aims to test the non-inferiority of an Allogenic Dermal Matrix with Platelet-Rich Fibrin for treatment of gingival recessions in comparison to the Connective Tissue Graft.
- Trial name
- NCT05819515
- Testing
- Tunneled coronally advanced flap
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Systemic Lupus Erythematosus, Lupus Nephritis
Systemic Immune Inflammatory Index in Systemic Lupus Erythematosus
This study aims to investigate the association between the systemic immune-inflammation index and disease activity, as well as lupus nephritis in patients with systemic lupus erythematosus
- Trial name
- NCT06796569
- Testing
- systemic immune inflammatory index
- Where
- Egypt
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Sohag University
Vital Pulp Therapies, Indirect Pulp Cap
Vital Pulp Treatment in Primary Teeth
In primary teeth, decay that is near the pulp (tooth nerve)is treated with either a pulpotomy or indirect pulp treatment if the tooth is not going to be extracted A pulpotomy involves removing the top 1/2 of the pulp, placing a…
- Conditions
- Vital Pulp Therapies, Indirect Pulp Cap, Pulpotomy
- Trial name
- NCT02298504
- Testing
- Mineral Trioxide Aggregate, Biodentin, Vitrebond
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Reversal of Local Anesthesia in Children
Phentolamine Mesylate vs. Diode Laser for Anaesthesia Reversal
"Randomised three-arm trial comparing phentolamine mesylate (OraVerse), 650-nm diode laser and no intervention for accelerating reversal of soft-tissue anaesthesia after 4% articaine (1:100,000 epinephrine) buccal infiltration in…
- Trial name
- RCT (NCT05473858)
- Testing
- OraVerse Injectable Product, diode laser
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- sara nabil
Dental Implant, Osseointegration
Assessment of Early Healing Period of Dental Implants
This prospective cohort study aimed to evaluate, clinically, radiographically, and digitally, the volumetric changes occurring during the early healing period after implant treatment in patients with tooth loss in the posterior…
- Conditions
- Dental Implant, Osseointegration, Biological Width
- Trial name
- NCT06554444
- Testing
- Dental Implant Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Educational Problems, Anatomical Pathological Condition
3D Resin Printed Fracture Models for Anatomy Education
Resin printing is an emerging technology with a wide array of applications. This research seeks to assess the practicality of incorporating 3D resin printed models into anatomy education while investigating how fractured models…
- Trial name
- NCT06061003
- Testing
- Clinical Anatomical Education with Fractured Bone Models, Clinical Anatomical Education with Standard Bone Models
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Glucose Metabolism Disorders, Hunger
Food Orders on Blood Glucose and Fuel Use at Rest
Consuming a carbohydrate-rich food as the final food in a meal, as compared to the first food in a meal, has been shown to reduce blood glucose levels after eating in both diabetes patients and in healthy controls.
- Conditions
- Glucose Metabolism Disorders, Hunger, Fat Burn
- Trial name
- NCT06763562
- Testing
- Carbohydrate-first meal, Carbohydrate-last meal
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Dynamic Knee Valgus, Agility
Frontal Plane Knee Projection Angle and Functional Performance in Adolescent Female Volleyball Players
This observational study aims to examine the relationship between frontal plane knee projection angle, dynamic balance, agility performance, and ankle dorsiflexion mobility in adolescent female volleyball players.
- Conditions
- Dynamic Knee Valgus, Agility, Dynamic Balance, Ankle Dorsiflexion
- Trial name
- FPPA-DBA (NCT07711236)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sinop University
Heart Failure
A Multimodal Wearable Platform for Heart Failure Disease Stratification
The purpose of this study is to find out if there are any patterns in the way people's bodies react to physical activities and their voices when they have heart failure, a disease where the heart cannot function sufficiently.
- Trial name
- WEAR-HF (NCT06335264)
- Testing
- Watch HOP
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Healthy Volunteers, Physical Fitness
Effects of 8-Week Mat Pilates and Reformer Pilates Exercises on Functional Movement Screen Scores and Joint Range of Motion in Recreationally Active Males
The goal of this clinical trial is to compare how 8 weeks of Mat Pilates and Reformer Pilates affect movement quality and joint flexibility in active young men.
- Trial name
- PILATES-FMS (NCT07869862)
- Testing
- Reformer Pilates Training, Mat Pilates Training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Renal Impairment
A Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics and Safety of VIR-2218
The rationale of this study is to evaluate the impact of renal function on the PK, safety, and tolerability of VIR-2218 in participants with normal renal function and participants with varying degrees of renal dysfunction who are…
- Trial name
- NCT05844228
- Testing
- VIR-2218
- Where
- 3 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Vir Biotechnology, Inc.
Influenza
Efficacy, Immunogenicity and Safety of OVX836 Influenza Vaccine 480μg
The present study will evaluate the efficacy, immunogenicity and safety of one dose of OVX836 influenza vaccine 480μg, after intramuscular administration in healthy subjects aged 18-59 years.
- Trial name
- NCT05569239
- Testing
- OVX836 480µg, Saline Solution
- Where
- 16 sites in Belgium, Finland and 2 more
- Volunteers
- 2,891 people, healthy volunteers welcome
- Sponsor
- Osivax
Probiotic
Heat-Inactivated Lactobacillus Salivarius HM-6 in Preschool Children With ECC
This study aims to evaluate whether a short, 14-day administration of chewable tablets containing heat-inactivated Lactobacillus salivarius HM-6 Paradens can influence selected salivary parameters related to oral health in…
- Trial name
- AEPRO (NCT07825324)
- Testing
- Children in the intervention group received commercially available chewable tablets containing 10 mg of heat-inactivated Lactobacillus salivarius HM-6 Paradens.
- Where
- Poland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Reading Disability
Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults
The goal of this project is to address the urgent need for effective, scalable adult literacy interventions by integrating breakthroughs in two separate fields: 1.) the brain network science of resilience to reading disorders and…
- Trial name
- NCT05523505
- Testing
- RLN real non-invasive brain stimulation intervention, RLN and CCN real non-invasive brain stimulation intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
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