Clinical trials: Cardiopulmonary Arrest
Cardiac Arrest, Cardiopulmonary Arrest
Quality of Pediatric Resuscitation in a Multicenter Collaborative
This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression…
- Trial name
- pediRES-Q (NCT02708134)
- Where
- 63 sites in United States, Australia and 13 more
- Volunteers
- 7,000 people
- Sponsor
- Children's Hospital of Philadelphia
Cardiac Arrest (CA), Cardiopulmonary Resuscitation (CPR)
The OXY-VENT Study
Adequate ventilation during cardiopulmonary resuscitation is essential to maintain oxygenated blood supply to vital organs, yet achieving guideline-adherent synchronous ventilation (two breaths per pause after 30 compressions…
- Trial name
- OXY-VENT (NCT07870551)
- Testing
- Ventilation Feedback Device (Active), Control (Recording-Only)
- Where
- Netherlands
- Volunteers
- 515 people
- Sponsor
- Jeroen van Eijk
Cardiac Arrest, Sudden, Cardiopulmonary Resuscitation (CPR)
The Influence of the Thoracic Stiffness of CPR Teaching Manikins on the Accuracy of Compression in Cardiopulmonary Resuscitation
This study was a multicenter, prospective, randomized controlled, parallel single-blind study. The purpose of this study is to analyze the effect of compression quality by controlling the thoracic stiffness.
- Conditions
- Cardiac Arrest, Sudden, Cardiopulmonary Resuscitation (CPR), Manikins
- Trial name
- NCT07861841
- Testing
- different elasticity coefficients of the manikin device
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Tang Ziren
Cardiac Arrest (CA), Pediatric Cardiac Arrest (Simulated)
Augmented Reality-Cardiopulmonary Resuscitation Support for Pediatric Resuscitation
This study evaluates whether an augmented reality cardiopulmonary resuscitation feedback system (AR-CPR) can support health care providers in delivering high-quality chest compressions during pediatric cardiac arrest.
- Conditions
- Cardiac Arrest (CA), Pediatric Cardiac Arrest (Simulated), Cardiopulmonary Resuscitation (CPR)
- Trial name
- AR-CPR (NCT07778823)
- Testing
- AR-CPR
- Where
- 8 sites in United States, Canada
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cardiovascular Diseases, Cardiovascular Diseases Risk
Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways
Cor360 is an observational study evaluating whether extended wearable electrocardiogram (ECG) data can support broad-spectrum cardiac phenotyping and risk assessment beyond conventional single-purpose ambulatory rhythm…
- Conditions
- Cardiovascular Diseases, Cardiovascular Diseases Risk, Cardiac Conduction System Disease, Bundle/Fascicular Abnormalities
- Trial name
- Cor360 (NCT07775976)
- Testing
- COR Wearable ECG Monitoring, Cor360 Clinician-Facing Decision-Aid Reporting
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Respiration Failure, Cardio Vascular Disease
COMPARE-VENT Feasibility Pilot Study
Cardiac disease complicated by respiratory insufficiency comprises the most frequent indication for cardiac intensive care unit (CICU) admission, with nearly one-third patients requiring advanced respiratory support and over 20%…
- Conditions
- Respiration Failure, Cardio Vascular Disease, Cardiogenic Pulmonary Oedema, Critical Illness
- Trial name
- NCT07656259
- Testing
- Volume Controlled Mode, Pressure Controlled Mode
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Mayo Clinic
Out-of-hospital Cardiac Arrest (OHCA), Agonal Breathing
CPR and Agonal Breathing Recognition Training for Police Officers
This study will evaluate an educational training program for police officers in New Taipei City, Taiwan. Police officers may arrive at out-of-hospital cardiac arrest events before emergency medical services and may be able to…
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), Agonal Breathing, Cardiopulmonary Resuscitation Training
- Trial name
- CPR-AB Police (NCT07695766)
- Testing
- CPR Refresher and Agonal Breathing Recognition Training
- Where
- Taiwan
- Volunteers
- 3,439 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Cardiovascular Diseases, Cardiopulmonary Arrest
The Effect of Web-Based Gamification Applications on Nursing Students' Learning Regarding Cardiopulmonary Resuscitation
In this study, the aim was to determine students' level of knowledge regarding cardiopulmonary resuscitation by using web-based gamification applications in nursing education, and additionally, to evaluate the secondary effects…
- Conditions
- Cardiovascular Diseases, Cardiopulmonary Arrest, Web-based Gamification
- Trial name
- NCT07689422
- Testing
- web-based gamification application
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Out of Hospital Cardiac Arrest, Extracorporeal Cardiopulmonary Resuscitation
The CPR, Pre-hospital ECPR and Early Reperfusion Study: A Target Trial Emulation
CHEER4TTE is a target trial emulation, designed to simulate a randomised controlled trial by utilising data from pre-existing data sources.
- Trial name
- CHEER4TTE (NCT07679737)
- Testing
- Extracorporeal cardiopulmonary resuscitation
- Where
- Australia
- Volunteers
- 250 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Emergencies, Cardiopulmonary Arrest
Simulation Trial of Telemedical Support for Paramedics
In the United States, the current standard of prehospital (i.e. outside of hospitals) emergency care for children with life-threatening illnesses in the community includes remote physician support for paramedics providing…
- Conditions
- Emergencies, Cardiopulmonary Arrest, Acute Respiratory Failure, Status Epilepticus
- Trial name
- R01 (NCT06441760)
- Testing
- Video teleconsultation, Audio support
- Where
- 9 sites in United States
- Volunteers
- 420 people
- Sponsor
- Boston Medical Center
Cardiac Arrest, Cardiopulmonary Resuscitation
Compression Is Life In Cardiac Arrest - Human Study (CILICA-HS).
The management of out-of-hospital cardiac arrest is complex and multifactorial. With an incidence between 5 and 15 per 10,000 (46,000 patients per year in France) and a survival rate of only 5% to 15%, the room for improvement…
- Trial name
- CILICA-HS (NCT03817892)
- Testing
- Guidance of the External Chest Compression, Rhythm of a relay 4 minutes
- Where
- 11 sites in France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Caen
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest
Compression Only CPR Versus Standard CPR in Out-Of-Hospital Cardiac Arrest - A Randomized Survival Study
Out-of-hospital cardiac arrest (OHCA) is one of the leading causes of mortality in the industrialized world. Bystander CPR before arrival of the Emergency Medical Service (EMS) is associated with an increased chance of survival.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiopulmonary Resuscitation
- Trial name
- TANGO2 (NCT03981107)
- Testing
- Chest Compression Only CPR (CO-CPR) performed by trained bystanders after instructions from dispatchers, Standard CPR (S-CPR) performed by trained bystanders after instructions from dispatchers
- Where
- 2 sites in Italy, Sweden
- Volunteers
- 3,260 people
- Sponsor
- Karolinska Institutet
Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation
PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)
The PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE) study is a pilot feasibility trial evaluating the implementation of pre-hospital targeted temperature management (TTM) using a wearable surface…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation, Death, Sudden, Cardiac, Therapeutic Hypothermia
- Trial name
- PRECEDENCE (NCT07421882)
- Testing
- CarbonCool® Cooling Vest
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Cardiopulmonary Resuscitation (CPR), Basic Life Support Training Course
Evaluation of Mixed Reality Cardiopulmonary Resuscitation Training
<Study Design> This study is a cluster-randomized, stratified, non-inferiority trial designed to evaluate the feasibility, efficacy, and educational effectiveness of HEROS 4.0, a mixed-reality (MR)-based cardiopulmonary…
- Conditions
- Cardiopulmonary Resuscitation (CPR), Basic Life Support Training Course, Cardiac Arrest (CA)
- Trial name
- HEROS 4 (NCT07363772)
- Testing
- HEROS 4.0, Conventional CPR training
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Arrest
Relevance of Reversible Causes During OHCA (Rebecca Study)
Management of the reversible causes in cardiac arrest is fundamental for successful treatment of out-of-hospital cardiac arrests.
- Trial name
- REBECCA (NCT05784480)
- Testing
- Checklist for evaluation of reversible causes
- Where
- 2 sites in Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Cardiac Arrest (CA), Extracorporeal Cardiopulmonary Resuscitation
Clinical Application of Low-Field Magnetic Resonance Imaging in Patients on Extracorporeal Cardiopulmonary Resuscitation
Timely identification of acute brain injury (ABI) patterns in patients with extracorporeal cardiopulmonary resuscitation (ECPR) is essential for prognostic assessment and optimization of clinical management, particularly…
- Conditions
- Cardiac Arrest (CA), Extracorporeal Cardiopulmonary Resuscitation, Acute Brain Injury
- Trial name
- NCT07526701
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Capital Medical University
Heart Arrest, Cardiac Arrest
Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR).
The investigators hypothesized that pre-arrival instructions would increase the likelihood of bystanders performing Cardiopulmonary Resuscitation (CPR).
- Conditions
- Heart Arrest, Cardiac Arrest, Cardiopulmonary Arrest, Out of Hospital Cardiac Arrest
- Trial name
- NCT02007499
- Testing
- Pre-Arrival Instructions
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Medical College of Wisconsin
Cardiopulmonary Arrest, Pediatric ALL
Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest
The International Liaison Committee on Resuscitation regularly publishes a Consensus on Science with Treatment Recommendations but guidelines can nevertheless differ when knowledge gaps persist.
- Conditions
- Cardiopulmonary Arrest, Pediatric ALL, Resuscitation
- Trial name
- NCT05474170
- Testing
- AHA resuscitation sequence, ERC resuscitation sequence
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Cardiac Arrest (CA), Cardiopulmonary Resuscitation
RescueDoppler- a Disruptive Ultrasound Solution for Improved Outcome After Cardiac Arrest.
RescueDoppler is an innovative, hands-free Doppler system designed for continuous monitoring of blood flow in the carotid artery, distinguishing between the presence and absence of a pulse.
- Conditions
- Cardiac Arrest (CA), Cardiopulmonary Resuscitation, Doppler Ultrasound
- Trial name
- RescueDoppler (NCT06599073)
- Testing
- RescueDoppler, Rescue
- Where
- 8 sites in Norway, Sweden
- Volunteers
- 285 people
- Sponsor
- Norwegian University of Science and Technology
Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR)
The AIR-CPR Study: AI-Guided Chest Compressions
The AIR-CPR project aims to improve survival rates for patients with Out-of-Hospital Cardiac Arrest (OHCA) by utilizing Artificial Intelligence (AI) to optimize chest compression locations.
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR), Aortic Valve Compression, Precision Resuscitation
- Trial name
- AIR-CPR (NCT07431710)
- Testing
- Device: AI-Enhanced Arterial Waveform Monitor (AIR-CPR App), AI-Guided Chest Compression Repositioning, Transesophageal Echocardiography (TEE)
- Where
- Taiwan
- Volunteers
- 255 people
- Sponsor
- Far Eastern Memorial Hospital