Clinical trials: Implants
Dental Implants
Variable-thread Versus Standard Dental Implants for Replacing Missing Teeth
Background and objectives: Primary and secondary implant stability remain the most relevant and reliable clinical indicator for long-term survival of dental implants.
- Trial name
- NCT06808854
- Testing
- Dental implant treatment (variable-thread implants), Dental implant treatment (standard implants)
- Where
- United Arab Emirates
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Atrial Fibrillation, Diastolic Dysfunction
Atrial Fibrillation: Chronic Beta-blocker Use Versus As-needed Rate Control Guided by Implantable Cardiac Monitor
The goal of this study is to test the feasibility of guiding as-needed pharmacological rate control of atrial fibrillation (AF) by implantable cardiac monitors and to assess the impact of continuous beta-blocker therapy versus…
- Conditions
- Atrial Fibrillation, Diastolic Dysfunction, HFpEF - Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT05745337
- Testing
- As needed pharmacological rate control with beta-blocker (metoprolol tartrate, metoprolol succinate) or calcium channel blocker (diltiazem, verapamil)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Vermont
Total Ankle Prosthesis
HINTEGRA Total Ankle Prosthesis Follow-up
The Hintegra® Total Ankle Prosthesis is a non constrained, three-component prosthesis that consists of a flat tibial component, an anatomically-shaped talar component, and a high-density polyethylene inlay.
- Trial name
- NCT01284972
- Where
- 6 sites in Austria, Canada and 4 more
- Volunteers
- 225 people
- Sponsor
- Integra LifeSciences Services
Prostate Cancer
Use of a Biodegradable Balloon for the Treatment of Prostate Cancer by Intensity Modulated Radiotherapy (BioPro-RCMI)
The benefit of dose escalation in radiotherapy (RT) for biochemical control of prostate cancer is a clearly established fact based on the results of different published prospective trials.
- Trial name
- BioPro-RCMI (NCT02478112)
- Testing
- Biodegradable balloon implant
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Oscar Lambret
Poor Aesthetics of Existing Restoration
Evaluation of the Aesthetic Outcomes of the Single Crowns Supported by Tissue Level Implants
The aim of this study is to review the long-term soft tissue stability and the long-term esthetic results of single crowns supported by tissue level implants placed in non-augmented healed sites.
- Trial name
- PES/WES (NCT02061930)
- Testing
- single crowns supported by implants
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Dental Implants
In the Treatment of Implants With Different Methods; Early Bone Loss and Patient Satisfaction
The aim of this clinical study is to compare two different approaches during dental implant applications. One group of patients in the study received flapless approach which is performed without surgical reflection of soft…
- Trial name
- NCT04459494
- Testing
- Flapless implant surgery., Conventional implant surgery.
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Cardiomyopathies, Primary, Arrhythmia
An Arrhythmia Risk Stratification and Genetic Trial
The prospective EUTrigTreat multi-center study is an observational, advanced diagnostics and genetic risk stratification trial in patients with standard indications for ICD treatment, with and without myocardial infarction in…
- Conditions
- Cardiomyopathies, Primary, Arrhythmia, Sudden Cardiac Death, Calcium Metabolism Disorders
- Trial name
- EUTrigTreat (NCT01209494)
- Where
- 4 sites in Belgium, Germany and 2 more
- Volunteers
- 672 people
- Sponsor
- University Medical Center Goettingen
Tooth Loss
Implant Survival After Insertion of Bone Level Tapered (BLT) Implant Ø 2.9 mm in the Clinical Practice Setting
The Straumann Bone Level Tapered (BLT) implant Ø 2.9 mm implant was developed to allow treatment of patients with single tooth gaps of small dimensions in the lateral and central incisor positions in the mandible and in the…
- Trial name
- NCT02699866
- Testing
- BLT Implant Ø 2.9 mm
- Where
- 5 sites in Germany
- Volunteers
- 46 people
- Sponsor
- Institut Straumann AG
Cochlear Implants
Investigating the Performance and Safety of the AudioKey 3, a Device That Provides Remote Control Options and Status Information for Compatible MED-EL Audio Processors, by Analyzing Data Logged by the App and Responses to a User Survey
Investigating the performance and safety of the AudioKey 3, a device that provides remote control options and status information for compatible MED-EL audio processors, by analyzing data logged by the app and responses to a user…
- Trial name
- NCT06817928
- Where
- Austria
- Volunteers
- 46 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
End Stage Macular Degeneration
A Study of an Implantable Miniature Telescope in Patients With With End-Stage AMD
Evaluation of pre and post-implantation management of patients with end-stage age-related macular degeneration (AMD) who have been implanted with the implantable telescope (IMT) under CE Mark indicated use.
- Trial name
- NCT00555165
- Testing
- Telescope prosthesis
- Where
- 4 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- VisionCare, Inc.
Dental Implant
Computer Guided Versus Freehand Dental Implant Surgery
This study's goal is to evaluate the efficacy of traditional rehabilitation with freehand implant implantation of partly or totally edentulous patients utilizing flapless or mini-flap procedures vs.
- Trial name
- dental implant (NCT06204692)
- Testing
- dental implant
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- October 6 University
Breast Reconstruction, Patient Education
Educational Session To Optimize Patient's Breast Reconstruction Experience at McMaster
This pilot study uses a randomized controlled trial design to introduce an educational session for breast reconstruction patients. Participants will be randomly assigned to the (1) control group or the (2) experimental group.
- Trial name
- RESTORE (NCT03743753)
- Testing
- Experimental
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Bone Loss
Socket Preservation for Dental Implant Site Development.
Changes in alveolar bone following teeth extraction can compromise implant placement. Socket preservation (alveolar ridge preservation) is considered as a surgical procedure employed to preserve the ridge volume within the…
- Trial name
- NCT03112772
- Testing
- Puros® Allograft, CopiOs® Cancellous Particulate
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Al Faisal Hospital
Hallux Limitus of Left Great Toe, Rheumatoid Arthritis
Mid-term Outcomes of First MTP Arthroplasty With Primus™ FGT Implant.
Foot silicone implants suffer from bad reputation on the market, due to poor results obtained with the first generations of implants.
- Conditions
- Hallux Limitus of Left Great Toe, Rheumatoid Arthritis, Arthritis of 1st Metatarsophalangeal Joint, Osteoarthritis
- Trial name
- NCT02350881
- Testing
- Primus FGTI (Flexible Great toe Implant)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Stryker Trauma and Extremities
Secondary Cataract Surgery, Aphakia
Comparison of Two Different Intraocular Lenses Implanted With Yamane Technique
In case of instability or rupture of capsular bag occurs during cataract surgery, Yamane technique is one of the options to fix intracocularlens' haptics.
- Conditions
- Secondary Cataract Surgery, Aphakia, Complicated Cataract Surgery
- Trial name
- NCT05912829
- Testing
- IOL Master 700, Casia-2, MS-39
- Where
- 2 sites in Austria
- Volunteers
- 50 people
- Sponsor
- Johannes Kepler University of Linz
Knee Osteoarthritis, Joint Pain
Femoral Rotation and Patellar Positioning After TKA
Analysis of patellar positioning in the trochlear groove after TKA with and without the use of dynamic tensioner.
- Conditions
- Knee Osteoarthritis, Joint Pain, Joint Instability, Patella Disorder
- Trial name
- NCT05871112
- Testing
- Use of dynamic tensioner
- Where
- Poland
- Volunteers
- 125 people
- Sponsor
- Medical University of Warsaw
Bleeding
Is Cerazette Use Before Nexplanon Insertion Predictive for Bleeding Pattern?
The purpose of the study is to examine how well three months preceding use of Cerazette progestin only pill predicts the bleeding pattern during following Nexplanon implant use.
- Trial name
- NCT01438736
- Testing
- Desogestrel 75 micrograms POP (Cerazette), Etonogestrel 68 mg implant (Nexplanon), Etonogestrel 68 mg subdermal implant
- Where
- Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VL-Medi Oy
Osteoarthritis
A Roentgen Stereophotogrammetric Analysis on Migration of Knee Prostheses.
The purpose of this study is to compare the early migration of two uncemented total knee arthroplasties with different metal coating. Only the tibial prosthesis plateau varies.
- Trial name
- Ti-Tan (NCT00138853)
- Testing
- Tibial component
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Arthroplasty of the MCP Joint
Use of Avanta Metacarpophalangeal (MCP) Joint Implant Finger Prosthesis, Humanitarian Use Device
The purpose of this study is to allow patients to undergo surgery with the SR™ MCP (Metacarpophalangeal) Implants for finger arthritis.
- Trial name
- NCT02244775
- Testing
- SR™MCP
- Where
- United States
- Sponsor
- Hospital for Special Surgery, New York
Implant Site Reaction
Peri-implant Soft Tissue Conditioning of Immediate Posterior Implants by CAD/CAM Socket Sealing Abutments
One of the major challenges one clinician can face while performing immediate placement on posterior area, is the ability of obtaining a hermetic primary closure of the soft tissue.
- Trial name
- NCT05276765
- Testing
- cad/cam socket sealing abutment, standard healing abutment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
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