Clinical trials: sponsored by Al-Azhar University
Excessive Gingival Display, Gingival Diseases
Botulinum Toxin Type A Versus Cross-Linked Hyaluronic Acid Filler Myomodulation for Non-Surgical Management of Excessive Gingival Display
This randomized controlled trial compared the clinical efficacy and patient satisfaction of two non-surgical treatments for excessive gingival display (gummy smile): botulinum toxin type A (BTX-A) and cross-linked hyaluronic acid…
- Conditions
- Excessive Gingival Display, Gingival Diseases, Gummy Smile, Esthetics, Dental
- Trial name
- NCT07715331
- Testing
- Botulinum Toxin Type A (Refinex®), Cross-Linked Hyaluronic Acid Filler (Juvéderm Voluma® with Lidocaine)
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Cesarean Section, Surgical Site Infection
Effect of Betadine Vaginal Cleansing Before Cesarean Section to Reduce Postoperative Infectious Morbidity
This randomized controlled trial aims to evaluate the efficacy of preoperative vaginal cleansing with 5% povidone-iodine in reducing postoperative infectious morbidity among women undergoing cesarean section.
- Conditions
- Cesarean Section, Surgical Site Infection, Endometritis
- Trial name
- NCT07715409
- Testing
- Povidone-iodine 5% solution
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mohamed Mousa Mohamed Mousa
Gingival Recessions
Development of an Artificial Intelligence-Based Clinical Image Model for Detection, Classification, and Management Recommendations of Anterior Gingival Recession
This study aims to develop and evaluate an artificial intelligence-based clinical image model for the detection, classification, and management recommendations of anterior gingival recession.
- Trial name
- NCT07693322
- Testing
- Artificial Intelligence-Based Clinical Image Analysis Model
- Where
- Egypt
- Volunteers
- 149 people
- Sponsor
- Al-Azhar University
Periodontal Disease, Periodontitis (Stage 3)
Omega-3 Plus Low-Dose Aspirin in Smokers With Stage III Periodontitis
This randomized double-blind placebo-controlled clinical trial aims to evaluate the clinical and biochemical effects of omega-3 fatty acids combined with low-dose aspirin as an adjunct to scaling and root planing (SRP) in smoker…
- Conditions
- Periodontal Disease, Periodontitis (Stage 3), Smoking Behaviors
- Trial name
- OASP (NCT07673185)
- Testing
- Omega-3 Fatty Acids (EPA plus DHA) plus low dose aspirin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Periodontal Diseases
Deep Learning-Based Measurement of Keratinized Gingiva Width Using Smartphone-Acquired Clinical Images
This study aims to develop and validate an artificial intelligence-based system for automated measurement of keratinized gingiva width using smartphone-acquired intraoral clinical photographs.
- Trial name
- NCT07689552
- Testing
- Artificial Intelligence-Based Keratinized Gingiva Width Assessment
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Skeletal Class II Malocclusion, Mandibular Retrognathia
Fixed Versus Conventional Twin Block Appliances for Skeletal Class II Malocclusion
This study compares two types of dental appliances a fixed Twin Block appliance and a conventional (removable) Twin Block appliance used to treat a bite problem called skeletal Class II malocclusion in growing children and…
- Trial name
- NCT07687927
- Testing
- Conventional Twin Block Appliance
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Depigmentation Treatment, Depigmentation
Effect of Co-enzyme Q10 and Vitamin C Alone or in Combination After a Surgical Gingival Depigmentation
This study aims to assess the clinical effectiveness of Co-enzyme Q10 and Vitamin C, applied individually or in combination after surgical gingival depigmentation.
- Trial name
- Effect of Coe (NCT07677826)
- Testing
- surgical depigmentation, Coenzyme Q10, Vitamin C
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Closed Sinus Lift, Apigenin Loaded Scaffold
Closed Sinus Lifting Using Xenograft With or Without Liposomal Apigenin-Loaded Scaffold
aims to evaluate the effectiveness of closed sinus lifting using xenograft with or without a liposomal Apigenin-loaded scaffold in the posterior maxilla.
- Trial name
- NCT07678749
- Testing
- sinus lifting
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Left Ventricular Myocardial Dysfunction, End-Stage Kidney Disease
Assessment of Left Ventricular Myocardial Dysfunction in Children With End-Stage Kidney Disease Using Two-Dimensional and Three-Dimensional Speckle-Tracking Echocardiography
The present study aimed to assess left ventricular myocardial dysfunction in children with chronic kidney disease using 2D and 3D speckle-tracking echocardiography.
- Conditions
- Left Ventricular Myocardial Dysfunction, End-Stage Kidney Disease, Two-Dimensional Speckle-Tracking Echocardiography, Three-Dimensional Speckle-Tracking Echocardiography
- Trial name
- NCT07678710
- Testing
- Two-Dimensional Speckle-Tracking Echocardiography (2D-STE), Three-Dimensional Speckle-Tracking Echocardiography (3D-STE)
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
CLASS II DIVISION 1 MALOCCLUSION
Twin-Block and LIPUS for TMJ Outcomes in Skeletal Class II Patients
Evaluation of the efficacy of early treatment of skeletal class II patients with twin-block in conjunction with low intensity pulsed ultrasound on temporomandibular joint region: a prospective clinical trial
- Trial name
- AlAzharU (NCT07676695)
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Leukoderma
NCMT Technique and Jodhpur Technique and Excimer Laser in Treatment of Non Vitiligo Leucoderma
This study aims to compare the efficacy and safety of Melanocyte Keratinocyte Transplantation Procedure (MKTP) combined with 308-nm excimer laser versus Jodhpur technique combined with 308-nm excimer laser in the treatment of…
- Trial name
- NCT07662915
- Testing
- Melanocyte Keratinocyte Transplantation Procedure (MKTP), Jodhpur Technique, 308-nm Excimer Laser
- Volunteers
- 22 people
- Sponsor
- Al-Azhar University
Orthodontic Treatment Efficiency
Bilogical Assesment During Intrusion of Lower Incisors
biological assesment during intrusion of lower incisors
- Trial name
- NCT07514403
- Testing
- Corticision
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Nasal Surgery, Snoring
Nasal Surgery in Snoring and Obstructive Sleep Apnea
This study aimed to evaluate the effect of isolated nasal surgery on sleep-disordered breathing, particularly apnea-hypopnea index (AHI) and snoring index (SI), Apnea index (AI) and minimal arterial oxygen saturation (MAO2) in…
- Conditions
- Nasal Surgery, Snoring, Obstructive Sleep Apnea
- Trial name
- NCT07622745
- Testing
- Septoplasty with partial inferior turbinectomy, Nasal polypectomy, Partial inferior turbinectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Chronic Obstructive Pulmonary Disease, Respiratory Failure
Sedation vs No Sedation in Mechanically Ventilated COPD Patients
This study aims to evaluate the safety and efficacy of no-sedation compared to daily interruption of sedation (DIS) in mechanically ventilated patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- SEDvsNO-COPD (NCT07620912)
- Testing
- Midalozam
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Narrow Urethral Plate Hypospadias
Evaluation of Slit-like Adjusted Mathieu Versus Onlay Island Flap for Hypospadias Repair in Pediatrics
Purpose** To compare the Slit-like Adjusted Mathieu (SLAM) technique versus the inner transverse preputial onlay island flap for repair of anterior and mid-penile hypospadias with narrow urethral plate, evaluating complication…
- Trial name
- NCT07592026
- Testing
- Slit-like Adjusted Mathieu, onlay island flap
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Osseointegration
Erythropoietin Gel Effect on Dental Implant Stability
Achieving and maintaining long-term osseointegration for dental implants is a key objective in the field of dentistry. The success of osseointegration is influenced by the surface treatment applied to dental implants.
- Trial name
- NCT06665451
- Testing
- Non coated dental implants, Erythropoietin gel coated implants
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Occlusion
Effects of Clear Aligners Versus Fixed Appliances on Occlusion After Treatment of Mild Anterior Crowding
The aim of this study is to evaluate effects of clear aligners versus fixed appliances on occlusion after treatment of mild anterior crowding a T-scan study.
- Trial name
- NCT05737290
- Testing
- Clear aligners, Fixed appliances
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Carious Lesion, Ready-made Crowns
The Relation Between Oral Hygiene and Microbial Load in the Oral Cavity After Restoring Primary Molars With Two Types of Ready-made Crowns
Following the restoration of primary molars with stainless steel and bioflex crowns, an evaluation of the current state of oral hygiene in relation to the amount of microorganisms and gingival health in the oral cavity will be…
- Trial name
- bioflex crown (NCT06767670)
- Testing
- stainless steel crown, bioflex crown
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Implant Supported Overdenture, Wear, Occlusal
Clinical Evaluation of Conventional and 3D-printed Implant-supported Overdentures Retained With New Attachment Systems
Randomized Crossover Clinical Trial Comparing Two Denture Designs (A and B) Retained by Two Locator Systems (ST and EMI) in Implant Overdenture Patients
- Trial name
- IODs (NCT07580534)
- Testing
- Crossover Assignment
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Malocclusion, Angle Class II, Division 1, Bimaxillary Protrusion
LLLLT vs Piezocision in Accelerating Orthodontic Canine Retraction
This comparative controlled clinical study aims to evaluate and compare the effectiveness of piezocision and low-level laser therapy (LLLT) as adjunctive interventions to accelerate orthodontic canine retraction.
- Conditions
- Malocclusion, Angle Class II, Division 1, Bimaxillary Protrusion, Class I Malocclusion
- Trial name
- NCT07466641
- Testing
- Low Level Laser Therapy, Piezocision
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Hesham Nabil Ali Al-Qamhawy