Clinical trials: Motor Execution
Symptomatic Neuroma, Phantom Limb Pain After Amputation
Evaluation of RPNI for Symptomatic Neuromas in Lower Limb Amputees
This prospective, observational cohort study evaluates the long-term outcomes of Regenerative Peripheral Nerve Interface (RPNI) surgery in patients with major lower extremity amputations suffering from symptomatic neuromas.
- Conditions
- Symptomatic Neuroma, Phantom Limb Pain After Amputation, Residual Limb Pain, Neuropathic Pain
- Trial name
- RPNI-AMPUTEE (NCT07420192)
- Testing
- Regenerative Peripheral Nerve Interface (RPNI) Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Saglik Bilimleri Universitesi
Brain Stimulation, Peripheral Nerve Stimulation
Glutamate Modulation of tDCS Over Premotor Cortex Combined With Peripheral Nerve Stimulation Promoted Observation-execution-related Cortical Excitability and Motor Learning
This study aimed to investigate whether concurrent tDCS over the PMC and PNS during action observation enhance observation-execution-related motor cortex excitability and improve motor performance, and to explore the underlying…
- Conditions
- Brain Stimulation, Peripheral Nerve Stimulation, Motor Observation, Cortical Excitability
- Trial name
- NCT06694909
- Testing
- tDCS + PNS with action observation, tDCS + PNS without action observation
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Neuropathic Pain, Phantom Limb Pain
Mindful SensoriMotor Therapy With Brain Modulation in Highly Impaired Extremities
Brief summary: This single-arm, pilot clinical investigation aims to evaluate Mindful SensoriMotor Therapy (MSMT) enhanced with brain modulation as a treatment of pain due to sensorimotor impairment, such as Phantom Limb Pain…
- Trial name
- NCT04897425
- Testing
- Mindful SensoriMotor Therapy Enhanced with Brain Modulation
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Chalmers University of Technology
Stroke, Neurorehabilitation
Motor Imagery and Motor Execution Based BCI in Stroke
About 50% of stroke patients are unable to live independently because of residual disability. Brain-computer interface (BCI) is based on closed-loop theory, which facilitates neurological remodeling by establishing a bridge…
- Conditions
- Stroke, Neurorehabilitation, Motor Imagery, Motor Execution
- Trial name
- BCI-MIME (NCT05634616)
- Testing
- Motor imagery and motor execution based BCI
- Where
- China
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Amyotrophic Lateral Sclerosis
From Movement Preparation to Gait Execution in ALS
This research program will focus on gait initiation and postural control in Amyotrophic Lateral Sclerosis (ALS) patients, by comparing patients with vs without postural instability (but also in comparison to controls), by using a…
- Trial name
- GAITALS (NCT01874808)
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Neurosciences
The Brain Activation During Different Motor Patterns in Healthy Adults
This study aims to investigate the brain activation during different motor patterns, including motor execution (ME), motor imagery (MI), action observation (AO) and mirror visual feedback (MVF).
- Trial name
- NCT04868929
- Where
- Taiwan
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke Sequelae, Brain Ischemia
EEG Based BCI for Upper Limb Rehabilitation in Stroke
Biomedical and Engineering approaches form a key element to neurological rehabilitation of upper limbs. Brain Computer Interface (BCI) using Motor execution and Motor Imagery are known to aid motor recovery in stroke.
- Trial name
- NCT04188132
- Testing
- EEG -BCI based Feedback for rehabilitation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Houston
Phantom Limb Pain
Phantom Motor Execution Via MPR, VR/AR, and SG, as a Treatment of PLP
This international, multi-center, double-blind, randomized, controlled clinical trial aims to evaluate the efficacy of Phantom Motor Execution (PME) and Phantom Motor Imagery (PMI) as treatments of Phantom Limb Pain (PLP).
- Trial name
- NCT03112928
- Testing
- Phantom Motor Execution, Phantom Motor Imagery
- Where
- 9 sites in United States, Canada and 5 more
- Volunteers
- 77 people
- Sponsor
- Integrum
Caffeine, Biomechanics
Effects of Caffeine Ingestion on the Biomechanics of Healthy Young Subjects
Caffeine is one of the few supplements that have enough scientific evidence to state that can notably improve performance, as different remarkable organizations in the sports nutrition context have classified it as an ergogenic…
- Conditions
- Caffeine, Biomechanics, Fatigue, Injuries
- Trial name
- NCT06039358
- Testing
- Caffeine., Cellulose.
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Phantom Limb, Motor Activity
The Effects of Targeted Phantom Motor Execution on Phantom Limb Control
Lower limb amputations account for more than 85% of all amputations. In Canada, it has been reported that transtibial amputation (TTA) is the most common level of amputation.
- Conditions
- Phantom Limb, Motor Activity, Amputation Stump, Amputation
- Trial name
- NCT05247827
- Testing
- Targeted phantom limb motor execution (exercise)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Stroke
Action Observation, Imagery and Execution for Stroke Rehabilitation
The specific study aims will be: 1. To investigate the short- and long-term treatment effects of action observation, imagery, and execution therapy (AOIE) compared with an action observation therapy (AO) group and a control…
- Trial name
- NCT03246139
- Testing
- Action observation, imagery & execution, Action observation, Control treatment
- Where
- 4 sites in Taiwan
- Volunteers
- 17 people
- Sponsor
- Chang Gung Memorial Hospital
Hereditary Spastic Paraplegia
Flexibility, Resistance, Aerobic, Movement Execution Training in Adults With Hereditary Spastic Paraplegia
Hereditary Spastic Paraplegia (HSP) is a diverse group of genetic neurological conditions causing progressive weakness and spasticity in the lower limbs, severely reducing balance and gait capabilities.
- Trial name
- FRAME (NCT06742697)
- Testing
- Flexibility, Resistance, Aerobic, Movement Execution training
- Where
- 2 sites in Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Eugenio Medea
Performance, Soccer
Caffeine vs. Carbohydrate Mouth Rinsing in Soccer
The present study evaluated the influence of carbohydrate mouth-rinsing (CHO-MR), caffeine mouth-rinsing (CAF-MR), and control-substance mouth rinses on Loughborough soccer passing test (LSPT) performance.
- Conditions
- Performance, Soccer, Caffeine and Carbohydrate, Cognitive Function
- Trial name
- CAFMR-CHOMR (NCT06881316)
- Testing
- Caffeine, CHO, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Autism, Autism Spectrum Disorder
A Kinematic Analysis of Motor Planning and Movement Execution of Children With Autism Spectrum Condition
Autism Spectrum Condition (ASC) is a behavioral syndrome characterized by a severe organizational disorder of thinking and major functions that regulate human adaptation.
- Trial name
- NCT06144775
- Testing
- Kinematics measures
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Multiple Sclerosis, Sclerosis
Aerobic Exercise for Remyelination in Multiple Sclerosis
This is a clinical trial to determine the feasibility of a stationary aerobic cycling intervention and explore if aerobic exercise independently promotes remyelination in people with multiple sclerosis (MS).
- Conditions
- Multiple Sclerosis, Sclerosis, Demyelinating Diseases, Autoimmune Diseases of the Nervous System
- Trial name
- NCT04539002
- Testing
- Aerobic exercise, Education Group Control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Oregon Health and Science University
Young Adults
Cortical Excitability and Typing Performance After Action Observation and Motor Execution
Goal: This study will aim to investigate the effects of different motor stimulation strategies-motor execution (ME) and action observation (AO)-on cortical excitability and typing performance in healthy individuals.
- Trial name
- NCT07009561
- Testing
- Motor Execution Typing Task, Action Observation of Typing Task
- Where
- United Arab Emirates
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Chronic Obstructive Pulmonary Disease, Type 2 Diabetes
Interactive Tool to Support Self-management Through Lifestyle Feedback, Aimed at Physical Activity of COPD/DM Patients
Rationale: Physical activity is an important factor for a healthy lifestyle. Although physical activity can delay complications and decrease the burden of the disease in chronically ill persons, their level of activity is often…
- Trial name
- RCTIt'sLiFe! (NCT01867970)
- Testing
- Tool, Self-management Support Program
- Where
- Netherlands
- Volunteers
- 240 people
- Sponsor
- Maastricht University Medical Center
Healthy
Fitt's Law MI Experiment
The aim of our study is to investigate the acute effects of real execution (RE) and motor imagery (MI) of Fitts law tasks on near and far transfer of learning.
- Trial name
- NCT04744597
- Testing
- Real execution of Fitts's law tasks, Motor imagery of Fitts's law tasks, Skip counting
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper
Healthy
Transcranial Magnetic Stimulation to Study Imagination of Movement
This study will use transcranial magnetic stimulation (TMS) to examine the relationship between cognitive processing and motor control by determining whether a part of the brain called the premotor cortex is essential to…
- Trial name
- NCT00046215
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)